Case Rep Gastrointest Med
August 2025
This case report describes a rare occurrence of nonsteroidal anti-inflammatory drugs (NSAID)-induced focal colonic granulomatous mass mimicking a malignant colonic mass. It highlights the diagnostic challenges of NSAID-related gastrointestinal complications and stresses the importance of considering such causes in similar presentations. Prompt recognition and withdrawal of the offending NSAID can prevent unnecessary surgical intervention and facilitate symptom resolution.
View Article and Find Full Text PDFCholangiocarcinoma (CCA), a rare biliary cancer, typically presents with nonspecific symptoms that hinder early diagnosis. Emerging metabolic risk factors are increasingly being recognized as contributors. We present the case of a 54-year-old woman with newly diagnosed metabolic dysfunction-associated steatotic liver disease and metabolic syndrome, who presented with acute abdominal pain and a subsequent liver biopsy-confirmed intrahepatic CCA.
View Article and Find Full Text PDFThis case describes a 46-year-old man presenting with epigastric pain, weight loss, and obstructive jaundice, initially misdiagnosed as pancreatic cancer due to a pancreatic head mass compressing the common bile duct. Intraoperative biopsies during an aborted Whipple procedure revealed coexisting autoimmune pancreatitis and Castleman disease. This case highlights the diagnostic challenges of Castleman disease, its potential association with autoimmune pancreatitis, and the critical role of histological analysis in differentiating it from malignancy.
View Article and Find Full Text PDFAthlete's hepatitis is a rare form of ischemic hepatitis caused by hypoxic liver injury during extreme physical exertion. We present the case of a 25-year-old healthy male who developed severe transaminitis after completing a half-marathon. He presented with syncope, hypotension, and hyperthermia, followed by markedly elevated liver enzymes.
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