Assessing Alzheimer's disease knowledge among Egyptian medical students in the context of recent educational reforms.

Background: Medical students are the future doctors and play an essential role in the management of health issues. Their understanding of Alzheimer's disease (AD) is not only required but also necessary to provide the best possible care to patients. The present study aimed to assess medical students' knowledge about AD within the context of the recent reform of the Egyptian medical educational system, which switched to competency-based instead of outcome-based education since 2017.

Preoperative oral caffeine as prophylaxis against post-spinal hypotension in patients undergoing orthopedic lower limb surgery: A randomized, placebo-controlled, double-blinded study.

Background: This study aimed to investigate the efficacy of preoperative a caffeine tablet as prophylaxis against post-spinal hypotension in adult patients undergoing lower extremity orthopedic surgery.

Methods: Patients aged 18-70 years who underwent lower limb orthopedic surgery were enrolled. In the caffeine group, the patient ingested a 200 mg caffeine tablet.

Beyond the usual challenges, a case of LV summit PVCs ablation in child with ASO for D-TGA.

Premature ventricular contractions (PVCs) are a common finding in patients with surgically repaired congenital heart defects including transposition of the great arteries (D-TGA). While often asymptomatic, PVCs can sometimes lead to palpitations, dyspnea, and hemodynamic compromise, requiring therapeutic intervention. The arterial switch operation is the preferred treatment for D-TGA, but these patients have a 2% incidence of ventricular arrhythmias and 1% incidence of sudden cardiac death post-operatively.

2D Carbon Phosphide for Trapping Sulfur in Rechargeable Li-S Batteries: Structure Design and Interfacial Chemistry.

Rechargeable lithium-sulfur batteries (LiSBs) assembled with earth-abundant and safe Li anodes are less prone to form dendrites on the surface, and sulfur-containing cathodes offer considerable potential for achieving high energy densities. Nevertheless, suitable sulfur host materials and their interaction with electrolytes are at present key factors that retard the commercial introduction of these batteries. Here we propose a two-dimensional metallic carbon phosphorus framework, namely, 2D CP, as a promising sulfur host material for inhibiting the shuttle effect and improving electronic conductivity in high-performance Li-S batteries.

Ultrasound-guided Serratus Anterior Plane Block Versus Paravertebral Block for Postoperative Analgesia in Children Undergoing Video-assisted Thoracoscopic Surgery: A Randomized, Comparative Study.

Objectives: This study compared the postoperative analgesic efficacy of serratus anterior plane block (SAPB) and thoracic paravertebral block (PVB) in children undergoing video-assisted thoracoscopic surgery.

Setting: Operating room and intensive care unit of a tertiary care hospital.

Design: A single-center, randomized, comparative, open-labeled study.

Validation of harmonized cognitive assessment protocol within the Egyptian context.

This study addresses the urgent need for culturally sensitive cognitive assessments in Egypt by validating an adapted version of Harmonized Cognitive Assessment Protocol (HCAP) to the Egyptian context. This version is to be used as a part of the Egyptian Aging Survey (AL-SEHA). We enrolled 300 participants aged 55 + from diverse backgrounds and meticulously adapted the HCAP for Egypt's linguistic and cultural context.

Ultrasonic chemical synthesis of zinc-manganese ferrites with improved magnetic properties.

Zinc-Manganese spinel ferrites (ZnMnFeO) are nowadays very attractive magnetic materials for cancer diagnostic and therapy. With the help of intense ultrasonic waves, sonochemical synthesis method was used to prepare stoichiometric and chemically homogenous nanoparticles by varying the manganese content. The crystal structure along with the size and shape of the as-prepared nanoparticles were described using XRD, TEM and FT-IR techniques, while cations distribution was carefully investigated using XPS and Mössbauer spectroscopic techniques and supported with density functional theory calculations.

Impairment of Nrf2 signaling in the hippocampus of P301S tauopathy mice model aligns with the cognitive impairment and the associated neuroinflammation.

Mice transgenic for human P301S tau protein exhibit many characteristics of the human tauopathies, including the formation of abundant hyperphoshorylated tau filaments, the associated neuroinflammation and disease phenotype. However, the exact underpinning mechanisms are still not fully addressed that hinder our understanding of the tauopathy diseases and the development of possible therapeutic targets.Methods: In the current study, hippocampus from three disease time points (2, 4 and 6 months) of P301S mice were further characterized in comparison to the age and sex matched control wild type mice (WT) that do not express the transgene.

Effect of Low-dose Ketamine Infusion on Opioid Consumption in Children Undergoing Open Cardiac Surgery: A Randomized Controlled Double-Blind Study.

Objective: This study was designed to evaluate the effect of low-dose ketamine infusion on the perioperative consumption of opioids in pediatric open cardiac surgery.

Design: A randomized, controlled, double-blinded single-center study was conducted.

Setting: The study took place in a tertiary care children's hospital.

Ultrasound-guided mid-point transverse process to pleura block versus thoracic paravertebral block in pediatric open-heart surgery: A randomized controlled non-inferiority study.

Study Objective: The mid-point transverse process to pleura block (MTPB) is a new variant of thoracic paravertebral block (TPVB). This study aimed to compare TPVB and MTPB with respect to intraoperative attenuation of the hemodynamic stress response to surgery and postoperative analgesia in pediatric open heart surgery with midline sternotomy.

Design: A single-center, randomized, controlled, double-blind, non-inferiority study.

Enabling High-Performance Hybrid Solid-State Batteries by Improving the Microstructure of Free-Standing LATP/LFP Composite Cathodes.

The phosphate lithium-ion conductor LiAlTi(PO) (LATP) is an economically attractive solid electrolyte for the fabrication of safe and robust solid-state batteries, but high sintering temperatures pose a material engineering challenge for the fabrication of cell components. In particular, the high surface roughness of composite cathodes resulting from enhanced crystal growth is detrimental to their integration into cells with practical energy density. In this work, we demonstrate that efficient free-standing ceramic cathodes of LATP and LiFePO (LFP) can be produced by using a scalable tape casting process.

Back to Old Books Toward Affordable Research: Homemade Phenol-Based Reagent for Triphasic RNA Purification.

Covid-19 crisis did hit many socio-economic aspects in the whole world. In the scientific research, the problem is getting even worse, since most of materials and consumable are allocated to the health sector. Many research laboratories around the world have big delay in receiving their purchases to accomplish their research projects.

Structural, dielectric and transport properties of NaFeMnO ( = 1 and 2/3).

NaFeMnO ( = 1 and 2/3) layered oxides were prepared by an improved solid-state synthesis method. The XRD analysis confirmed the high purity of these samples. The Rietveld refinement of the crystalline structure illustrated that the prepared materials crystallize in a hexagonal system in the space group with the P3 structure for = 1 and in a rhombohedral system with the 6/ space group and P2 structure type for = 2/3.

Galectins dysregulation: A way for cancer cells to invade and pervade.

Galectins are sticky molecules that bind to β-galactoside. Their interactions render them essential players in many cellular processes. The imbalance of galectin expression was reported in many diseases.

Bilateral Ultrasound-Guided Mid-Point Transverse Process to Pleura Block for Perioperative Analgesia in Pediatric Cardiac Surgery: A Randomized Controlled Study.

Objective: Mid-point transverse process to pleura (MTP) block is a new regional analgesia technique. This study aimed to assess the perioperative analgesic effects of MTP block in children undergoing open-heart surgery.

Design: A single-center, randomized, double-blinded, controlled, superiority study.

Sodium Rich Vanadium Oxy-Fluorophosphate - Na Ni V (PO ) F O - as Advanced Cathode for Sodium Ion Batteries.

Conventional sodium-based layered oxide cathodes are extremely air sensitive and possess poor electrochemical performance along with safety concerns when operating at high voltage. The polyanion phosphate, Na V (PO ) stands out as an excellent candidate due to its high nominal voltage, ambient air stability, and long cycle life. The caveat is that Na V (PO ) can only exhibit reversible capacities in the range of 100 mAh g , 20% below its theoretical capacity.

Investigation of structural, morphological, and electrical conductivity study for understanding transport mechanisms of perovskite CHNHHgCl.

Along with morphological and structural studies, the temperature and frequency dependence of the electrical and dielectric properties of the CHNHHgCl (MATM) compound was investigated and analyzed. SEM/EDS and XRPD analyses proved the purity, composition, and perovskite structure of the MATM. DSC analysis reveals the existence of an order-disorder phase transition of a first-order type at about 342 ± 2 K and 320 ± 1 K (heating and cooling, respectively), attributed to the disorder of [CHNH] ions.

Homemade plasmid Miniprep solutions for affordable research in low-fund laboratories.

As a consequence of Covid-19 pandemic, the basic lab consumables are in shortage, especially in the low-income countries. Thus, the main objective of the present study is to develop and evaluate homemade solution to isolate plasmid. To pursue this objective, RNase A was overexpressed in Bl21 DE3 cells (E.

Assessment of galectins -1, -3, -4, -8, and -9 expression in ovarian carcinoma patients with clinical implications.

Background And Aim: Galectins have been recently tackled by many researchers in the field of cancer due to their role in tumorigenesis, disease progression, and metastasis. Thus, they are currently involved in biomarkers research on several types of cancer. In ovarian cancers, few studies were carried out to evaluate galectins expression profiling.

In-house protocol: spin-based viral RNA purification.

A worldwide shortage of molecular biology consumables is in surge. This includes filter tips, nucleic acid purification kits, polymerases, reverse-transcriptase, and different types of reagents which are included in viral diagnostic kits. In developing countries, the problem is even worse, since there is few capital enterprise to adopt this kind of industry.

Structural, optical, electric and dielectric characterization of a NaCuFeMnO compound.

The compound NaCuFeMnO was synthesized using a solid-state method and it crystallized in a hexagonal system with a 3̄ space group in an O3-type phase. The optical properties were measured using UV-Vis absorption spectrometry to determine the absorption coefficient and the optical band gap . The optical band gap energy of this sample is 2.

Revitalizing Fertility of Nutrient-Deficient Virgin Sandy Soil Using Leguminous Biocompost Boosts Performance.

During the 2019 and 2020 seasons, nutrient-deficient virgin sandy soil was examined along with the investigation of the response of plants to soil application with biocompost in integration with chemical fertilizers applied to soil and plants. Four treatments (100% of the recommended NPK fertilizer dose (control), 75% NPK applied to soil + 25% foliar spray, 75% NPK applied to soil + 25% foliar spray + leguminous compost (C), and 75% NPK applied to soil + 25% foliar spray + C containing (biocompost; CB)) were applied in a randomized complete block design. The 75% NPK applied to soil + 25% foliar spray + CB was the best treatment, which exceeded other treatments in improving soil fertility and plant performance.

Efficient production of few-layer black phosphorus by liquid-phase exfoliation.

Phosphorene is a new two-dimensional material that has recently attracted much attention owing to its fascinating electrical, optical, thermal and chemical properties. Here, we report on high-quality exfoliation of black phosphorus nanosheets, with controllable size produced in large quantities by liquid-phase exfoliation using -methyl-2-pyrrolidone (NMP) as a solvent under ambient conditions. The as-synthesized few layers show a great potential for solar energy conversion based on the optical results shown in this work.

Phonon Spectroscopy in Antimony and Tellurium Oxides.

α-SbO (senarmontite), β-SbO (valentinite), and α-TeO (paratellurite) are compounds with pronounced stereochemically active Sb and Te lone pairs. The vibrational and lattice properties of each have been previously studied but often lead to incomplete or unreliable results due to modes being inactive in infrared or Raman spectroscopy. Here, we present a study of the relationship between bonding and lattice dynamics of these compounds.