Novel antibacterial, antioxidant, and anti-inflammatory aminated chitosan hybrid quinoline Schiff base as multi-target agent: Design, molecular docking, and toxicity assessment.

This study involves the synthesis of a novel 7-ethoxy-3-formyl-2-morpholino quinoline (MQ) derivative, which was hybridized with aminated chitosan (AMCH) to yield a new AMCH-MQ Schiff base. Structural characterization via H NMR, FTIR, electronic spectra, XRD, and TGA confirmed successful hybridization. Ion exchange capacity decreased from 28.

Multisystemic Tuberculosis Masquerading as Aggressive Cardiac Tumor Causing Budd-Chiari Syndrome Disseminated to the Brain Resulting in Death of a Six-Year-Old Boy.

Tuberculosis (TB) is an ancient and re-emerging granulomatous infectious disease that continues to challenge public health. Early diagnosis and prompt effective treatment are crucial for preventing disease progression and reducing both morbidity and mortality. These steps play a vital role in infection control and in lowering death rates at both individual and population levels.

Early perceptions of portfolios in an outcome-based curriculum.

Background: Despite the widespread use of portfolios in medical education, their outcomes remain variable. This study evaluated students' perceptions of portfolios at an institution that recently adopted an outcome-based curriculum.

Methods: This descriptive cross-sectional study involved 4th, 5th, and 6th -year medical students (n = 94; response rate = 64.

Assessment of the impact of carotid intima-media thickness on postoperative cognitive dysfunction following elective noncardiac surgery.

Background: Postoperative cognitive dysfunction (POCD) following noncardiac surgery in the elderly is a growing concern. This study evaluates the relationship between carotid intima-media thickness (cIMT), a measure of subclinical atherosclerosis, and POCD.

Methods: In this prospective study, elderly patients (≥60 years) undergoing elective noncardiac surgery were divided into two groups based on cIMT.