Online functional connectivity analysis of large all-to-all networks in MNE Scan.

The analysis of electroencephalography (EEG)/magnetoencephalography (MEG) functional connectivity has become an important tool in neuroscience. Especially the high time resolution of EEG/MEG enables important insight into the functioning of the human brain. To date, functional connectivity is commonly estimated offline, that is, after the conclusion of the experiment.

Dexamethasone for prevention of AMS, HACE, and HAPE and for limiting impairment of performance after rapid ascent to high altitude: a narrative review.

Acute exposure to high altitude can cause acute altitude illnesses and is associated with impaired cognitive and physical performance. The most effective preventive strategies currently recommended include environmental acclimatization (slow ascent and/or pre-acclimatization) or pharmacological support of acclimatization using acetazolamide. However, these strategies are not practical for high-altitude exposures that require rapid and unplanned ascent, high physical and mental performance, such as rescue missions or military operations.

Screening for Left Ventricular Hypertrophy Using Artificial Intelligence Algorithms Based on 12 Leads of the Electrocardiogram-Applicable in Clinical Practice?-Critical Literature Review with Meta-Analysis.

The increasing utilization of artificial intelligence (AI) in the medical field holds the potential to address the global shortage of doctors. However, various challenges, such as usability, privacy, inequality, and misdiagnosis, complicate its application. This literature review focuses on AI's role in cardiology, specifically its impact on the diagnostic accuracy of AI algorithms analyzing 12-lead electrocardiograms (ECGs) to detect left ventricular hypertrophy (LVH).

Air quality, respiratory health and performance in athletes: a summary of the IOC consensus subgroup narrative review on 'Acute Respiratory Illness in Athletes'.

With the WHO stating that nearly 99% of the global population is exposed to air pollution levels that increase the risk of chronic diseases, the question of exercising in polluted environments is relevant to the health of athletes. Major sporting events held under conditions of poor air quality (AQ) have highlighted the lack of answers to concerns raised by organisers and athletes about the associated health risks. This evidence-based narrative review compiles current knowledge and identifies gaps regarding the relationship between AQ and sport.

Strategic Responses to Employee Well-Being Issues in VUCA (Volatile, Uncertain, Complex, and Ambiguous) Conditions: Expanding the JD-R (Job Demands-Resources) Model with Job Crafting.

Current work environments, driven by globalization, demographic changes, and digitalization, demand substantial adaptation, which leads to decreased employee well-being. While occupational psychology research has identified supportive mechanisms, it often lacks a deepened understanding of how interventions function. This study aims to analyze the impacts of VUCA contexts and leadership behavior on job crafting, focusing on white-collar workers.

The contribution of motor identity prediction to temporal binding.

Temporal binding describes an illusory compression of time between voluntary actions and their effects. In two experiments, using stable, preexisting action-effect associations, we investigated whether motor identity prediction (prediction of the effect's identity) enhances temporal binding. Touch-typists performed keystrokes and were presented with congruent (corresponding letter) or incongruent (noncorresponding letter) effects after different intervals.

Low-dose carbon monoxide inhalation to increase total hemoglobin mass and endurance performance: scientific evidence and implications.

Recently, chronic intermittent inhalation of low-dose carbon monoxide (CO) has been postulated as a practice to increase total hemoglobin mass with potential beneficial effects on endurance performance. In this perspective article, we discuss the potential performance enhancing capabilities as well as the safety concerns, which include individual variability in CO response, and acute and chronic health effects. It is also important to note that according to the World-Anti-Doping-Agency (WADA), CO inhalation could fall under "" and therefore could be considered a prohibited method if used as a non-diagnostic tool.

What individual needs do family caregivers have in palliative home care and how are they supported? A qualitative study of a supportive intervention.

Purpose: Family caregivers (FCGs) play a pivotal role in supporting patients in palliative care at home. Person-centred support is crucial to prevent negative outcomes; therefore, evidence-based approaches such as the Carer Support Needs Assessment Tool Intervention (CSNAT-I) are promising. To understand more about the delivery of the intervention, the study focuses on documentation of CSNAT-I in practice in Austria to identify which support needs were discussed with the FCGs and the types of support delivered to meet these needs.

Albumin in Normovolemic Fluid Management for Severe Traumatic Brain Injury: Controversies and Research Gaps.

Traumatic brain injury (TBI) is a significant public health issue characterized by high mortality rates and long-term complications. This commentary examines the controversial role of the use of albumin in the fluid management of patients with severe TBI. Despite its physiological benefits, the clinical use of albumin remains controversial due to the fact that various studies have yielded mixed results.

Sport climbing performance determinants and functional testing methods: A systematic review.

Background: Sport climbing is becoming incredibly popular both in the general population and among athletes. No consensus exists regarding evidence-based sport-specific performance evaluation; therefore, this systematic review was aimed at analyzing determinants of sport climbing performance and evaluation methods by comparing climbers of different levels.

Methods: PubMed, Scopus, and Web of Science were searched up to December 20,2022.

Flying to high-altitude destinations.

Every year millions of people fly to high-altitude destinations. They thereby expose themselves to specific high-altitude conditions. The hypoxic environment (low ambient oxygen availability) constitutes a major factor affecting health and well-being at high altitude.

The Potentials of Digital Workplace Health Promotion.

Workplace Health Promotion (WHP) can sustainably impact organizations by improving employee health and strengthening legitimization. Digital Workplace Health Promotion (DWHP) may have even more impact thanks to its scope. This study reports on a hospital in Austria wherein DWPH was introduced into the existing WHP structure in combination with a digitalization effort for the entire organization.

Altitude illnesses.

Millions of people visit high-altitude regions annually and more than 80 million live permanently above 2,500 m. Acute high-altitude exposure can trigger high-altitude illnesses (HAIs), including acute mountain sickness (AMS), high-altitude cerebral oedema (HACE) and high-altitude pulmonary oedema (HAPE). Chronic mountain sickness (CMS) can affect high-altitude resident populations worldwide.

Robotic-assisted total knee arthroplasty is not associated with improved accuracy in implant position and alignment compared to conventional instrumentation in the execution of a preoperative digital plan.

Purpose: The primary objective of the present study was to evaluate if robotic-assisted total knee arthroplasty (RO-TKA) results in improved accuracy compared to conventional TKA (CO-TKA) with respect to alignment and component positioning executing a preoperative digital plan. The secondary objective was to compare patient-reported outcome measures (PROMs) between the two groups at 6 months of follow-up (FU).

Methods: Patients who underwent primary TKA using the concept of constitutional alignment were identified from the database.

Impact of the COVID-19 Pandemic on Therapy and Outcome of Acute Exacerbations of Chronic Obstructive Lung Disease at the Emergency Department.

This study compared the treatment outcomes of acute exacerbation of COPD (AECOPD) at an academic tertiary care emergency department before and during the COVID-19 pandemic. Analyzing data from 976 patients, our study showed a significant surge in overall respiratory therapy interventions amidst the noticeable decline in the total number of AECOPD cases during the pandemic. The marked increase in the utilization of non-invasive ventilation (NIV) was particularly important, soaring from 12% to 18% during the pandemic.

Patient-Reported Outcome and Experience Measures (PROM/PREM) in Patients Undergoing Liver Surgery with Enhanced Recovery after Surgery (ERAS): An Exploratory Study.

Background: ERAS (Enhanced Recovery after Surgery) is an evidence-based multidisciplinary approach focusing on optimizing outcomes after surgery through structured clinical pathways. This study aimed to assess patient-reported outcome and experience measures (PROM/PREM), which are not routinely assessed after liver surgery within an ERAS protocol.

Methods: Routine outcome parameters were extracted from clinical documentation.

Technology-Supported Behavior Change-Applying Design Thinking to mHealth Application Development.

Non-communicable diseases are the leading cause of global deaths. The risk of their development and progression is increased by modifiable behavioral risk factors. Yet, despite the known benefits of primary and secondary prevention, people often do not follow recommendations for a healthier lifestyle.

Global sensitivity of EEG source analysis to tissue conductivity uncertainties.

Introduction: To reliably solve the EEG inverse problem, accurate EEG forward solutions based on a detailed, individual volume conductor model of the head are essential. A crucial-but often neglected-aspect in generating a volume conductor model is the choice of the tissue conductivities, as these may vary from subject to subject. In this study, we investigate the sensitivity of EEG forward and inverse solutions to tissue conductivity uncertainties for sources distributed over the whole cortex surface.

Penetrance, cancer incidence and survival in HFE haemochromatosis-A population-based cohort study.

Background And Aims: Haemochromatosis is characterized by progressive iron overload affecting the liver and can cause cirrhosis and hepatocellular carcinoma. Most haemochromatosis patients are homozygous for p.C282Y in HFE, but only a minority of individuals with this genotype will develop the disease.

Adoption Processes of Innovations in Health Systems: The Example of Telemedicine in Germany.

(1) Background: Individual adoption experiences represent important factors in implementing innovations. In the context of health systems, where the implementation of innovations aims to improve the quality of care, they provide an important basis for developing and adapting implementation strategies. (2) Methods: This study examines the adoption experiences of (tele-)medical experts ( = 13) using the example of telemedicine in the German healthcare system by means of a qualitative, guideline-based interview study.

Location Matters-Can a Smart Golf Club Detect Where the Club Face Hits the Ball?

In golf, the location of the impact, where the clubhead hits the ball, is of imperative nature for a successful ballflight. Direct feedback to the athlete where he/she hits the ball could improve a practice session. Currently, this information can be measured via, e.

Community Health Nursing Education in Austria-The Need for Competences in Planning, Management and Collaboration: A Problem-Centered Qualitative Study.

(1) Background: The Austrian health care system is extremely fragmented. Primary care is mainly provided by self-employed GPs. Other health professionals are rarely integrated into primary care.

Mechanisms underlying the health benefits of intermittent hypoxia conditioning.

Intermittent hypoxia (IH) is commonly associated with pathological conditions, particularly obstructive sleep apnoea. However, IH is also increasingly used to enhance health and performance and is emerging as a potent non-pharmacological intervention against numerous diseases. Whether IH is detrimental or beneficial for health is largely determined by the intensity, duration, number and frequency of the hypoxic exposures and by the specific responses they engender.

A German translation and validation of the sense of agency scale.

Sense of agency refers to the experience of controlling one's actions and through them events in the outside world. General agency beliefs can be measured with the Sense of Agency Scale (SoAS), which consists of the sense of positive agency subscale (i.e.

Optical Measurement of Ligament Strain: Opportunities and Limitations for Intraoperative Application.

A feasible and precise method to measure ligament strain during surgical interventions could significantly enhance the quality of ligament reconstructions. However, all existing scientific approaches to measure in vivo ligament strain possess at least one significant disadvantage, such as the impairment of the anatomical structure. Seeking a more advantageous method, this paper proposes defining medical and technical requirements for a non-destructive, optical measurement technique.