A Plant-Based Dietary Supplement Exhibits Significant Effects on Markers of Oxidative Stress, Inflammation, and Immune Response in Subjects Recovering from Respiratory Viral Infection: A Randomized, Double-Blind Clinical Study Using Vitamin C as a Positive Control.

Respiratory viruses continue to present serious health challenges to human wellness. Growing evidence suggests that the more severe and damaging effects and symptoms of influenza, rhinovirus (RV), respiratory syncytial virus (RSV), and COVID-19 may primarily result from their common ability to disorganize the body's healthy immune response. The simultaneous over-stimulation of several reactive oxygen species (ROS) pathways and concurrent suppression of bioavailable Nitic Oxide (NO) contribute to an immune disbalance that can lead to cellular oxidative distress and an excessive inflammatory response.

The semi-structured interview for bipolar at-risk states (SIBARS): psychometric properties and validation.

Background: Established psychometric instruments to detect individuals at high-risk of bipolar disorders (BD) are essential to advance preventive approaches.

Methods: The Semi-structured Interview for Bipolar At-Risk States (SIBARS)'s psychometric properties were evaluated through: (i) dimensionality (confirmatory factor analysis, CFA); (ii) reliability (internal/inter-rater reliability); and (iii) validity in terms of convergent validity (Hamilton Depression Rating Scale, HAM-D, Mini-International Neuropsychiatric Interview, MINI; Temperament Evaluation of Memphis, Pisa, and San Diego Autoquestionnaire, TEMPS-A; Young Mania Rating Scale, YMRS), divergent validity (Comprehensive Assessment of At-Risk Mental States, CAARMS; Hamilton Anxiety Rating Scale, HAM-A), concurrent criterion validity (Bipolar Prodrome Symptom Interview and Scale-Abbreviated Screen for Patients, BPSS-AS-P).

Results: A total of 193 participants were included.

Microscope-Free Analyte Detection Based on Fiber-Optic Gliding Motility Assays.

Prolonged hospital waiting times are linked with increased patient mortality and cause additional financial burdens on institutions. Efficient point-of-care diagnosis would help alleviate this, but is hampered by a lack of cost-effective devices capable of rapid, in situ, wide ranging analyte detection. Lab-on-fiber technology provides an answer allowing for diagnosis, treatment, and monitoring in situ with real time feedback.

Personality Functioning in Inpatients With Eating Disorders: Association With Symptom Severity and Treatment Outcome.

Objective: Impairment in personality functioning (PF) has been linked to a number of mental disorders, including eating disorders (EDs). However, the precise relationship between PF and symptom severity, as well as the potential impact on outcome, remains unclear. The study aimed to analyse the association of PF and its change with severity of ED symptomatology as well as outcome of hospital treatment.

In-Situ Monitoring the Magnetotransport Signature of Topological Transitions in a Chiral Magnet.

Emerging magnetic fields related to the presence of topologically protected spin textures such as skyrmions are expected to give rise to additional, topology-related contributions to the Hall effect. In order to doubtlessly identify this so-called topological Hall effect, it is crucial to disentangle such contributions from the anomalous Hall effect. This necessitates a direct correlation of the transversal Hall voltage with the underlying magnetic textures.