Electronic cigarettes and cardiovascular diseases: An updated systematic review and network meta-analysis.

Introduction: The association between electronic cigarettes (e-cigarettes) and the risk of cardiovascular disease (CVD) remains inconclusive. This study aims to compare CVD risk from the use of e-cigarettes, cigarettes, combined cigarette and e-cigarette use, and non-use.

Methods: This study is a systematic review and network meta-analysis (NMA).

Quality of life and influencing factors among older adults in the end of COVID-19 era: A cross-sectional study.

Introduction: The COVID-19 pandemic has impacted all age groups, with older individuals experiencing health effects and lifestyle changes. This study explored factors associated with quality of life (QoL) among older adults and examined how a history of COVID-19 infection and quarantine varied across these factors in the post-pandemic period.

Methods: A cross-sectional survey was conducted among older adults attending a primary care clinic between November 2023 and January 2024.

Efficacy of N-acetylcysteine dexamethasone in preventing postembolization syndrome post-transarterial chemoembolization in hepatocellular carcinoma: A randomized controlled trial.

Background: Hepatocellular carcinoma (HCC) is a major health concern in Thailand, with most patients diagnosed at the intermediate stage. Transarterial chemoembolization (TACE) is the standard treatment; however, postembolization syndrome (PES) remains a common complication. Although both dexamethasone (DEXA) and N-acetylcysteine (NAC) have shown efficacy in reducing PES, no study has directly compared their effects.

Metabolomic insights into rotenone-induced dysregulation of purine metabolism and impaired insulin secretion in murine pancreatic beta cells.

Rotenone, an insecticide, and herbicide has been associated with various environmental and health concerns. This study investigates the molecular alterations in rotenone-treated murine pancreatic beta cells, using untargeted metabolomics based on liquid chromatography-mass spectrometry. We established a model mimicking rotenone toxicity in MIN6 cells and observed decreased insulin secretion despite no significant loss of cellular viability.

PM2.5 risk perception and associated with sociodemographic factors in urban Thailand.

Long-term exposure to particulate matter (PM2.5) primarily affects the respiratory and cardiovascular systems, resulting in millions of premature deaths per year. However, the influence of PM2.

Biguanides are associated with decreased early mortality and risk of acute kidney injury in hospitalised patients with COVID-19: a nationwide retrospective cohort study in Japan.

Background: The most prescribed oral glucose-lowering medication worldwide is biguanide (BG), which shows potential for further therapeutic applications. The coronavirus disease 2019 (COVID-19) pandemic is a global public health emergency. Nevertheless, low-cost treatments against COVID-19 have not been established, with varying morbidity and mortality rates in each country.

Association Between Residual Kidney Function and Frailty in End-Stage Renal Disease Patients Undergoing Hemodialysis: A Cross-Sectional Study.

Background: Residual kidney function (RKF) plays a crucial role in maintaining biochemical balance in hemodialysis patients. Frailty, commonly observed in end-stage renal disease (ESRD) patients, is associated with metabolic derangements, inflammation, and fluid overload. However, the relationship between RKF and frailty in this population remains unclear.

Clinical Characteristics and Treatment Outcomes of Breakthrough Vitreous Hemorrhage in Peripheral Exudative Hemorrhagic Chorioretinopathy (PEHCR).

Purpose: To evaluate the clinical characteristics and treatment outcomes of breakthrough vitreous hemorrhage secondary to peripheral exudative hemorrhagic chorioretinopathy (PEHCR).

Methods: This retrospective study included 14 eyes from 14 patients with vitreous hemorrhage secondary to peripheral retinochoroidal mass lesions. Data collected included demographic profiles, clinical presentation, multimodal imaging findings, and treatment outcomes following pars plana vitrectomy (PPV), intravitreal anti-VEGF injections, or laser photocoagulation.

The Course of the Main Trunk and Parietal Branch of the Superficial Temporal Artery for a Pterional Scalp Flap with Superficial Temporal Artery Preservation: Cadaveric and Clinical Study.

Background: The pterional incision is usually performed near the course of the superficial temporal artery (STA), which carries a risk of injury to a branch or even the main trunk of the STA (mSTA). In this study, we assessed the usual course of the mSTA and its parietal branch of the STA (pSTA) and evaluated the efficacy of a modified pterional scalp incision for the preservation of all STA branches.

Materials And Methods: Sixteen sides of cadaveric heads were dissected to study the location and paths of the mSTA and pSTA in the vicinity of the ear cartilage and the oculomeatal (OM) line.

Anatomy of the Fibrofatty Adhesion Related to the Frontozygomatic Process for Suprafascial Dissection of the Pterional Scalp Flap: A Cadaveric and Clinical Study.

Background: With the existence of the fibrofatty adhesion (FFA) in the temporal region in relation to the frontotemporal branch of the facial nerve, the suprafascial dissection technique for two-layer pterional scalp flap creation was developed for standard pterional craniotomy. However, the exact anatomy of the FFA has not been well described. We clarified the anatomy of the FFA in cadavers and clinical cases.

Two-Decade Retrospective Analysis of Postoperative Endophthalmitis at a Tertiary Care Academic Center: Microbial Spectrum, Treatment Modalities, and Visual Outcomes.

Purpose: To determine the causative microorganisms, treatment modalities, visual outcomes, and factors influencing the results of postoperative endophthalmitis at a major tertiary referral eye care facility in Thailand.

Patients And Methods: A retrospective review was conducted on patients diagnosed with postoperative endophthalmitis over a 20-year period. The collected data included demographic characteristics, endophthalmitis classification, causative organisms, treatment modalities, and final visual acuity.

Clinical Features and Optical Coherence Tomography Angiography in Neovascular Age-Related Macular Degeneration and Pachychoroid Neovasculopathy.

To investigate differences in baseline characteristics, outcomes, and metrics of swept-source optical coherence tomography (SS-OCT) angiography between drusen-associated neovascular age-related macular degeneration (nAMD) vs pachychoroid neovasculopathy. This prospective cohort study enrolled 1 eye per patient with treatment-naïve nAMD or pachychoroid neovasculopathy who underwent 3 monthly bevacizumab injections followed by a treat-and-extend regimen for 12 months or longer. Eligible patients were classified into 2 groups: those with drusen-associated nAMD and those with pachychoroid neovasculopathy.

Ruthenium-106 Plaque Brachytherapy for the Management of Intraocular Tumors in Thailand: The First Report from Southeast Asia.

Background: Report the results of Ruthenium plaque brachytherapy (Ru) for the management of intraocular tumors in Thailand.

Methods: We retrospectively reviewed the medical records of 46 eyes of 45 patients who received Ru brachytherapy for the treatment of various intraocular tumors in the Department of Ophthalmology of Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, between April 2013 and December 2020.

Results: Of 46 eyes, 21 (46%) were diagnosed with small to medium choroidal melanoma, 13 (28%) with retinoblastoma, 4 (9%) with choroidal metastases, 2 (4%) with retinal vasoproliferative tumor (VPT), 3 (7%) with choroidal hemangioma (CH), 2 (4%) with RPE adenoma, and 1 (2%) with retinal hemangioblastoma.

Development and Validation of KN-DIOC: A Novel Preoperative Diagnostic Index Using Ultrasound, Complete Blood Count, and Cancer Antigen 125 for Ovarian Cancer.

Background: Ovarian cancer, particularly epithelial ovarian cancer (EOC), is one of the deadliest gynecological malignancies due to nonspecific early symptoms and late diagnosis. Current diagnostic tools, while useful, often do not account for regional variations in disease presentation, particularly in Asian populations. This study aimed to develop and validate a new preoperative diagnostic index tailored to the Thai population by integrating complete blood count (CBC), tumor markers, and ultrasound features.

Distribution of metacercariae and cyprinoid fish abundance in Nong Han Wetland, Thailand.

Opisthorchiasis, caused by , remains a public health concern in Southeast Asia, particularly in Thailand. This study investigates the prevalence and intensity of metacercariae in cyprinoid fish from the Nong Han Wetland in Northeast Thailand, and assesses fish abundance and environmental factors influencing parasite distribution. Fish were sampled monthly at eight sites during the rainy (June - October 2024) and dry (November 2024 - March 2025) seasons.

Translation, validity, and reliability of the Thai de Morton Mobility Index in patients following hip surgery.

Objective: This study aimed to translate the de Morton Mobility Index (DEMMI) into Thai and assess its measurement properties.

Methods: The de Morton Mobility Index (DEMMI) was translated into Thai using a cross-cultural translation method. A cross-sectional study was conducted in four public hospitals in Thailand between January and March 2023.

Alcoholic vs. aqueous chlorhexidine for abdominal surgery skin preparation: a randomized controlled trial.

Surgical site infections (SSIs) significantly affect patient outcomes and healthcare costs. Alcohol-based chlorhexidine gluconate (CHG) is widely used for preoperative skin preparation; however, aqueous CHG is being considered as a safer alternative in certain settings. This study was designed as an equivalence randomized controlled trial to compare aqueous versus alcoholic CHG for surgical site infection (SSI) prevention in major abdominal operations.

Timing of Newborn Hearing Screening Effects on Passing Rates: A Prospective Cohort Study.

Newborn hearing screening using transient evoked otoacoustic emissions (TEOAEs) is essential for early detection of hearing impairment. The Joint Committee on Infant Hearing recommends screening near hospital discharge but does not specify an optimal timing. To determine the optimal timing for TEOAE screening in neonates at low risk of hearing impairment and to identify perinatal factors influencing pass rates.

Persistent Congenital Tibial Pseudoarthrosis until Adulthood Treated with Vascularised Fibular Graft: A 17-year Follow-up.

A 39-year-old woman diagnosed with persistent congenital tibial pseudoarthrosis until adulthood presented with a right leg angular deformity, associated pain, and significant limb length discrepancy. Over a 17-year period, the case was closely monitored and treated through excision of the pseudarthrosis, vascularised fibular graft with bone marrow-derived and cultured mesenchymal cells, combined with highly purified β-tricalcium phosphates, internal fixation, and the application of a ring Ilizarov fixator. The successful union of bones and correction of deformities was achieved through consideration of both mechanical and biological aspects.

Preservation of the infrapatellar fat pad during total knee arthroplasty reduces subacute postoperative anterior knee pain: a randomized controlled trial.

Background: Preservation of the infrapatellar fat pad (IPFP) during total knee arthroplasty (TKA) is associated with a lower incidence of postoperative anterior knee pain (AKP). However, the comparative efficacy of IPFP preservation remains unclear. The objective of this randomized controlled trial (RCT) was to compare the incidence of AKP between IPFP preservation and partial excision of the IPFP.

Radiographic evaluation of radial styloid features in de Quervain's tenosynovitis: a case-control study.

Purpose: De Quervain's tenosynovitis (DQV) is a common tendinopathy characterized by inflammation of the first extensor compartment, resulting in pain on the radial side of the wrist. While clinical assessment is primarily utilized for diagnosis, radiographic imaging may be essential for ruling out alternative conditions. This study aimed to investigate specific radiographic measurements of the radial styloid and their correlation with DQV.

Development and Feasibility of a Smartphone Application for Promoting Healthy Heart Behaviors Following Open-Heart Surgery: A Mixed-Method Pilot Study.

Adherence to healthy behaviors after open-heart surgery is crucial for recovery and long-term health. Traditional patient education methods can be enhanced by using technology to improve engagement and self-care. This study aimed to develop and assess the feasibility of the "Term-Jai" smartphone application for promoting healthy heart behaviors in open-heart surgery patients.

Dating Application Use and Its Relationship with Mental Health Outcomes Among Men Who Have Sex with Men in Urban Areas of Thailand: A Nationwide Online Cross-Sectional Survey.

Dating applications (DAs) are widely used to establish social and sexual connections among men who have sex with men (MSM), particularly in urban areas. In this study, we aimed to examine the associations between DA use and mental health among Thai MSM. An online cross-sectional survey was completed by 442 MSM residing in Bangkok and urban municipalities across all regions of Thailand.

The Work Engagement Among Nurses in an Urban-Based Tertiary Hospital.

: Work engagement is essential to the well-being of nurses and the quality of health care, particularly in high-demand urban hospital environments in Bangkok. To determine the levels of work engagement-vigor, dedication, and absorption-among nurses in a Thai urban tertiary hospital, and to identify associated demographic and occupational predictors. : A cross-sectional study was conducted among 650 nurses at a tertiary university hospital in Bangkok, Thailand, from February to March 2025.