Development and Characterization of Nutritious Gluten-Free Doughnuts with Lupin and Inulin Flours.

Celiac disease is an immune-mediated disease caused by ingestion of gluten-containing products. The main aim of this study was to develop novel gluten-free doughnuts with high nutritional value using inulin and lupin flour. Five different doughnuts were formulated.

Vancomycin prescribing and therapeutic drug monitoring: Challenges of real clinical practice.

Background: Vancomycin prescription and monitoring guidelines have been reported to be poorly followed by various centers.

Aims: Identifying barriers to compliance with vancomycin dosing and therapeutic drug monitoring guidelines (TDM) and possible ways to enhance compliance based on the healthcare providers' (HCPs) perspective.

Methods: A qualitative study based on semi-structured interviews with HCP (physicians, pharmacists, and nurses) was conducted at two Jordanian Teaching Hospitals.

Perceived barriers to effective use of telehealth in managing the care of patients with cardiovascular diseases: a qualitative study exploring healthcare professionals' views in Jordan.

Background: The use of telehealth in the management of care and care delivery has been increasing significantly during the COVID-19 pandemic. Telehealth is an emerging technology used to manage care for patients with cardiovascular diseases (CVDs) in Jordan. However, implementing this approach in Jordan faces many challenges that need to be explored to identify practical solutions.

Acute Stanford Type A Aortic Dissection: A Review of Risk Factors and Outcomes.

Acute aortic dissection (AAD) can be said to be a relatively uncommon emergency with fatal outcomes mainly due to delayed/missed diagnosis and treatment. Its ability to masquerade as other emergencies like acute coronary syndrome and pulmonary embolism makes the prognosis unfavorable in a significant proportion of patients. Patients have been seen to present to the accident and emergency department or outpatient setting with typical or atypical symptoms as we will discuss in this article.

Clinical Reproducibility and Reliability of Lever Sign (Lelli's) Test for Acute ACL Tear Performed by Medical Students.

Background: Injuries to the anterior cruciate ligament (ACL) in sports are frequent in children and young adults participating in sporting activities involving rotational and pivoting movements. Magnetic resonance imaging is the most accurate diagnostic tool to detect an ACL tear. There are, however, a number of specialized tests available to assess ACL competency.

Using the Superfolder GFP (sfGFP) System to Study Plant Peroxisomal Protein Import.

The fusing of a protein of interest to a fluorescent protein followed by fluorescence microscopy is a very common method of determining protein localization and dynamics. However even small fluorescent proteins can be large enough to affect protein folding and localization, therefore the ability to use a smaller tag but still be able to detect a fluorescent signal in live cell imaging experiments is extremely valuable. The self-assembling split sfGFP system allows the fusion of the protein of interest with the 11th β-strand of super-folder GFP (sfGFP11) which is only 13 amino acids long.

Specifying a cascade water demand forecasting model using time-series analysis: a case of Jordan.

This study aims to develop a model for forecasting water demand for 2021-2030 to examine water availability for municipality uses in the Al-Balqa governorate of Jordan. The method was developed using a time series analysis of historical data from 1990-2010, which comprised yearly and monthly water consumption and socioeconomic factors, including population, income, and climate factors, such as average precipitation and temperatures. The analysis of historical data was conducted using the Statistical Package for the Social Sciences.

A Systematic Review of CD34+ Stem Cell Therapy as an Innovative and Efficient Treatment for the Management of Refractory Angina.

Despite optimal medical treatment, many individuals suffering from severe coronary artery disease are not suitable candidates for further revascularization. Therapeutic angiogenesis has attracted continuous interest to increase myocardial perfusion. Cell therapy using autologous stem cells expressing Cluster of Differentiation 34 plus (CD34+) offers a special therapeutic choice for individuals with refractory angina, seeing as CD34+ stem cells can restore microcirculation.

What Dietary Patterns and Nutrients are Associated with Pancreatic Cancer? Literature Review.

This narrative review summarizes the main findings of observational studies (case-control and cohort) as well as systematic reviews and meta-analyses on the role of nutrients and dietary patterns on pancreatic cancer (PC) risk and elucidates possible mechanisms for the association between nutrients or specific food components and the risk of PC. A literature search of MEDLINE (PubMed), Google Scholar, ScienceDirect, and Scopus was performed. An extensive search of related articles published in the English language from 1985 to 2022 was carried out.

Emphasis on Icosapent Ethyl for Cardiovascular Risk Reduction: A Systematic Review.

Despite the widespread use of lipid-lowering agents such as statins, cardiovascular disease (CVD) remains the leading cause of mortality worldwide. Icosapent ethyl (IPE) (Vascepa), an ethyl ester of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA), has gained widespread popularity as an adjunctive agent that targets multiple and additional mechanisms linked to the incidence of cardiovascular (CV) events and the causative pathway of atherosclerosis. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 standards were used to conduct this systematic review.

Macronutrients Not Micronutrients Are Associated With the Risk of Pancreatic Cancer: A Jordanian Case-Control Study.

Objectives: Pancreatic cancer (PC) has been related directly to many risk factors; however, diet is considered one of the most modifiable risk factors. This study is designed to observe the associations between the intake of macromicronutrients and the risk of pancreatic cancer in a Jordanian population.

Methods: A case-control study included 100 patients with the incident and histologically confirmed PC and 309 control subjects frequency-matched on age, educational level, occupation, and marital status.

The Safety of Minimally Invasive and Open Cholecystectomy in Elderly Patients With Acute Cholecystitis: A Systematic Review.

Elderly patients with acute cholecystitis (AC) often receive no surgical treatment due to a high number of comorbidities and a high risk of operations. With an increasingly aged population worldwide, this systematic review aims to review the safety of minimally invasive cholecystectomy and open cholecystectomy in this population compared to younger patients. A systematic search was conducted on PubMed, PubMed Central, and Google Scholar databases on July 2, 2022.

Reconstructing the anal sphincters to reverse iatrogenic overstretching following a pull-through for Hirschsprung disease. One-year outcomes.

Background: In patients with Hirschsprung disease (HSCR), soiling may be related to anal sphincter damage following the initial pull-through. No optimal treatment has been developed for such patients, although enemas (rectal or antegrade) have been applied with some success. We present the one-year outcomes of a new technique for anal sphincter reconstruction.

Field electron emission from tungsten micro-tips coated with various thicknesses of polystyrene nanolayers: Characteristics & analysis.

This paper studies and analyses the characteristics of cold field electron emission from uncoated polycrystalline tungsten tips before and after being coated with an insulating polystyrene layer of different thicknesses. The process of testing the samples has been carried out under high vacuum conditions (10 mbar). Uncoated tungsten tips were prepared using the electrochemical etching process.

Impact of COVID-19 lockdown on smoking (waterpipe and cigarette) and participants' BMI across various sociodemographic groups in Arab countries in the Mediterranean Region.

Introduction: Tobacco smokers are at high risk of developing severe COVID-19. Lockdown was a chosen strategy to deal with the spread of infectious diseases; nonetheless, it influenced people's eating and smoking behaviors. The main objective of this study is to determine the impact of the COVID-19 lockdown on smoking (waterpipe and cigarette) behavior and its associations with sociodemographic characteristics and body mass index.

Clinical Instructors' Caring Behaviors as Perceived by Nursing Students.

Caring is considered a vital aspect of nursing. This study explored Jordanian nursing students' perceptions of their clinical instructors' caring behaviors. A cross-sectional approach was taken.

Teachers' psychological resistance to digital innovation in jordanian entrepreneurship and business schools: Moderation of teachers' psychology and attitude toward educational technologies.

The current study aimed to highlight the factors that may influence teachers' psychological resistance to digital technologies in entrepreneurship and business schools. Theoretically grounded in the diffusion of innovations theory and the theory of planned behavior, the current research investigates teachers' psychological resistance to digital innovation, school culture and climate, and moderation of teacher attitudes toward educational technologies. A cross-sectional field survey of 600 business and entrepreneurship school teachers was conducted in Jordan.

Integration of GIS and remote sensing to derive spatially continuous thermal comfort and degree days across the populated areas in Jordan.

The widespread availability of high-resolution digital elevation data and high computational capabilities, along with GIS tools, has revolutionized big data processing, management, and interpolation. The present investigation generates high spatial resolution maps of thermal comfort levels, heating (HDD), and cooling (CDD) degree days across the populated areas in Jordan. Results show that areas having indoor apparent temperature (IAT) of 26 °C or above, which represents warm/hot conditions on this thermal index, cover a large portion of the study area during July and August.

Enhancement Properties of Zr Modified Porous Clay Heterostructures for Adsorption of Basic-Blue 41 Dye: Equilibrium, Regeneration, and Single Batch Design Adsorber.

Zirconium porous clay heterostructures (Zr-PCH) were synthesized using intercalated clay minerals by zirconium species with different contents of zirconium. The presence of zirconium and silica species was confirmed by X-ray diffraction, X-ray fluorescence, and magic-angle spinning nuclear magnetic resonance. The insertion of zirconium improved the thermal stability, the specific surface area with a maximum of 950 m/g, and the acidity concentration of 0.

Production of medium-sized chitosan oligomers using molecular sieves and their antibacterial activity.

Chitosan, derived from the natural polysaccharide chitin, was fragmented in very dilute acetic acid solutions using zeolites and molecular sieves, a type of zeolites, under variable reaction conditions of temperature, acid concentration, duration of reaction, and zeolites of variable pore sizes. Fragmentation resulted in the formation of appreciable amounts of chitosan oligomers comprised of 4-8 units, which were studied by using LC-MS, MS, as well as IR spectroscopy. The prepared fragments were tested for their biological activity and some of them showed antibacterial activity against Gram-positive bacteria.

Fetal and Newborn Management of Cloacal Malformations.

Cloaca is a rare, complex malformation encompassing the genitourinary and anorectal tract of the female in which these tracts fail to separate in utero, resulting in a single perineal orifice. Prenatal sonography detects a few cases with findings such as renal and urinary tract malformations, intraluminal calcifications, dilated bowel, ambiguous genitalia, a cystic pelvic mass, or identification of other associated anomalies prompting further imaging. Multi-disciplinary collaboration between neonatology, pediatric surgery, urology, and gynecology is paramount to achieving safe outcomes.

Laparoscopic Partial Nephrectomy: Off-Clamp Versus on Clamp.

Purpose: The aim of this study is to describe our experience in laparoscopic partial nephrectomy and to compare the differences between off-clamp and on-clamp techniques in terms of clinical characteristics and outcomes.

Methods: A retrospective study was utilized. A purposeful sampling method was used to select the patients.

Diabetic foot ulcer in Southern Jordan: A cross-sectional Study of Clinical and Microbiological Aspects.

Background: Diabetes mellitus (DM) is a common metabolic disorder that significantly affects public health. Diabetic foot ulcer (DFU) is one of the serious complications of diabetes. DFU has a wide spectrum of bacterial isolates comprising Gram-positive, Gram-negative, aerobic bacteria and anaerobes.