An unusual survival for 6.5 years with end-stage hepatitis C related advanced liver cirrhosis following sustained virologic response with direct antiviral agents - A case report from A low-resource setting.

Advanced chronic liver disease is frequently complicated by hepatic encephalopathy (HE), hepatorenal syndrome, and spontaneous bacterial peritonitis; predictors of poor prognosis that significantly reduce survival. While orthotopic liver transplantation (OLT) remains the definitive treatment, it is often inaccessible in resource-limited settings. We present the case of a 70-year-old retired hospital attendant with hypertension who developed decompensated liver cirrhosis secondary to chronic hepatitis C virus HCV infection.

Predictors of Non-Communicable Disease Risk Factors Among People Living with HIV and HIV-Negative Patients in a Nigerian Tertiary Hospital.

Purpose: In recent years, People Living with HIV (PLHIV) in sub-Saharan Africa have experienced a growing burden of non-communicable diseases (NCDs), straining already limited health systems. Identifying behavioural risk factors for NCDs in both PLHIV and HIV-negative individuals is essential for designing targeted interventions. This study aimed to identify common risk factors for NCDs in these groups and determine their predictors.

Common haematological malignancies in Northeastern Nigeria: a multi-centre study of their pattern, distribution and treatment challenges.

Background: Haematological malignancies (HMs) are primary cancers of the blood and blood-forming organs. They are heterogeneous and of diverse clinical features, treatment protocols and prognoses. They constitute a significant source of cancer-related morbidity and mortality.

Prevalence and determinants of intimate partner violence in pregnancy: a multicentre, binational study.

Background: Globally, intimate partners are the most common perpetrators of violence against women. Sub-Saharan Africa (SSA) contributes significantly to the burden of intimate partner violence (IPV) in Africa, with four of every 10 women in SSA having experienced IPV. When IPV occurs in pregnancy, it is significantly associated with adverse outcomes.

The pattern and burden of non-communicable diseases in armed conflict-exposed populations in Northeastern Nigeria.

Background: The risk of non-communicable diseases (NCDs) in conflict and post-conflict settings in Northeastern Nigeria has not been evaluated to date. As this region undergoes recovery, understanding the prevalence of NCDs, such as hypertension, diabetes, depression, and obesity, and the associated behavioral coping mechanisms, is crucial for developing tailored healthcare solutions. Therefore, this study aimed to assess the impact of conflict on the prevalence of NCDs in conflict-exposed areas in Northeastern Nigeria compared with non-conflict regions.

Transorbital subfrontal arrowhead injury: Experience in a low-resource setting.

Background: With the insurgency and farmer-herder crisis in northeast Nigeria, arrow injuries with various fatalities have been on the increase. Practicing in a low-resource setting with no functional computed tomography (CT) scan necessitates utmost dependence on plain X-rays for decision-making in patient care.

Case Description: We present our experience with a patient who presented in our facility with a right transorbital subfrontal arrow injury.

Elevated risk of pre-diabetes and diabetes in people with past history of COVID-19 in northeastern Nigeria.

Background: An increased risk of diabetes mellitus (DM) after COVID-19 has been reported in the United States, Europe, and Asia. The burden of COVID-related DM has yet to be described in Africa, where the overall risk of DM has been increasing rapidly. Our objective was to compare the prevalence of pre-DM and DM in Nigerian individuals with a history of COVID-19 to individuals without known COVID-19 infection.

Knowledge and Perception of Telemedicine among Medical Students of the University of Jos, Plateau State, Nigeria.

Background: Telemedicine has promising potential to address the challenges faced by healthcare systems in developing countries, in providing equitable access to quality care. However, the practice of telemedicine is generally poor in these countries. The success of telemedicine like any technology depends on numerous factors including users' knowledge and perceptions.

Prevalence and Pattern of Hearing Loss among Young Adults in Tertiary Institutions with Habitual Headphone/Earphone Usage in Kaduna Metropolis.

Background: World Health Organisation estimates that 1.1 billion young people worldwide could be at risk of hearing loss due to unsafe listening practises and nearly half of the teenagers and young adults are exposed to unsafe levels of sound from the use of personal audio devices.

Aim: This study aimed to determine the prevalence and pattern of hearing loss among students with habitual use of headphone/earphone in tertiary institutions in Kaduna.

Antimicrobial susceptibility pattern of extended-spectrum beta-lactamase-producing uropathogens in aminu Kano teaching hospital, Northwestern Nigeria.

Background: UTI is the most common nosocomial infection among hospitalized patients. Emerging increasing resistance has been observed among uropathogens of the family enterobacterales. Extended spectrum beta lactamase genes encode for multidrug resistance and unrestricted use of antibiotics in hospitals provides an environment for spread of infections with limited treatment options.

Coronavirus Disease 2019 Vaccination Coverage and Seropositivity amongst Nigerians 18 Years Old and Above.

Background: This was a cross-sectional community-based survey to study the prevalence of serum antibodies against the severe acute respiratory syndrome coronavirus 1 (SARS-COV-1) and determine possible source of antibodies as to whether from vaccination or from natural infection as well as attempt to compare antibody levels in response to the different four types of vaccines administered in Nigeria.

Methods: A cross-sectional community-based study of the prevalence of serum antibodies against all four vaccine types used in Nigeria amongst a representative sample of people aged 18 years and above in the six geopolitical zones of the country using a multistage sampling technique covering 12 states of the country with two states being randomly selected from each geopolitical zone. High-throughput Roche electrochemiluminescence immunoassay system (Elecsys Anti-SARS-COV-1 Cobas) was used for qualitative and quantitative detection of antibodies to SARS-COV-1 in human plasma.

Corrigendum: The epidemiological trend of monkeypox and monkeypox-varicella zoster viruses co-infection in North-Eastern Nigeria.

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A multicenter survey of asymptomatic cryptococcal antigenemia among patients with advanced HIV disease in Nigeria.

As of 2018, cryptococcal antigen (CrAg) screening in patients with advanced human immunodeficiency virus (HIV) disease (AHD) was not routinely implemented in Nigeria despite being recommended in the national HIV treatment guidelines. Our aim was to determine the prevalence and risk factors for asymptomatic cryptococcal antigenemia in adult people living with HIV (PLHIV) in Nigeria to advocate for the implementation of routine CrAg screening. A descriptive cross-sectional study and CrAg screening of consecutive adult PLHIV with CD4 counts ≤200 cells/μL was conducted from April 2018 to April 2019 at HIV clinics in eleven tertiary hospitals spread across Nigeria's six geopolitical regions.

The epidemiological trend of monkeypox and monkeypox-varicella zoster viruses co-infection in North-Eastern Nigeria.

Background: Monkeypox (MPX) is endemic in Nigeria, but it was first reported in Adamawa state, North-Eastern Nigeria, in January 2022. There are currently 172 cases of MPX in Nigeria, with four reported deaths, and Adamawa has the second-highest case count. Therefore, this study was undertaken to evaluate the epidemiological profile of this viral disease.

Risk Factors for COVID-19 Infection among Healthcare Workers in North-East Nigeria.

Healthcare workers (HCWs) face an unprecedented higher risk of COVID-19 infection due to their work and exposure. In this study, we aim to examine the associated risk factors for COVID-19 infection among HCWs in North-East Nigeria. We used data collected retrospectively among a cohort of clinical and non-clinical HCWs in six healthcare facilities in Adamawa State, Nigeria.