817 results match your criteria: "Institute of Applied Mechanics[Affiliation]"

Rupture of the anterior cruciate ligament (ACL) is a severe injury common in sports. It also has a high rate of re-injury. The aim of this work was to assess hamstring muscle fatigue in active football players after ACL reconstruction who were cleared to play and to determine symmetry between the lateral and medial hamstring muscles.

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Ti-6Al-4V is the most commonly used alpha-beta titanium alloy, making it the most prevalent among all titanium alloys. The processed material is widely employed in aerospace, medical, and other industries requiring moderate strength, a good strength-to-weight ratio, and favorable corrosion resistance. A microfinishing process on the titanium alloy surface was conducted using abrasive films with grain sizes of 30, 12, and 9 μm.

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The optomechanical motion of a gold nanoparticle (GNP) dimer-a pair of optically bound GNPs-in fluid, manipulated by a Bessel beam, is theoretically studied using the multiple multipole (MMP) method. Since a Bessel beam possesses orbital angular momentum (OAM) and spin angular momentum (SAM) simultaneously, complicated rigid-body motions of the dimer can be induced. The mechanism involves the equilibrium between the optical force with the reactive drag force exerted by the fluid.

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Background: The intricate process of coronary in-stent restenosis (ISR) involves the interplay between different mediators, including platelet-derived growth factor, transforming growth factor-β, extracellular matrix, smooth muscle cells, endothelial cells, and drug elution from the stent. Modeling such complex multiphysics phenomena demands extensive computational resources and time.

Methods: This paper proposes a novel non-intrusive data-driven reduced order modeling approach for the underlying multiphysics time-dependent parametrized problem.

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Article Synopsis
  • * The plasma treatment significantly improved the electrode's performance by reducing overpotential—790 mV at 100 mA/cm and 368 mV at 10 mA/cm—and lowering charge transfer resistance from 2.8 to 1.2 Ω.
  • * Testing in an anion exchange membrane water electrolysis system showed that at 70 °C and 100 mA/cm, the treated electrode achieved an energy efficiency of 95.1% and reduced specific energy consumption, suggesting it could be a cost-effective and eco
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Behavior of Microbubbles on Air-Aqueous Interfaces.

Langmuir

November 2024

Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford OX3 7LD, U.K.

Animal-derived lung surfactants have saved millions of lives of preterm neonates with neonatal Respiratory Distress Syndrome (nRDS). However, a replacement for animal-derived lung surfactants has been sought for decades due to its high manufacturing cost, inaccessibility in low-income countries, and failure to show efficacy when nebulized. This study investigated the use of lipid-coated microbubbles as potential replacements for exogenous lung surfactants.

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The lateral flow immunoassay (LFIA) is predominant in rapid diagnostic tests owing to its cost-effectiveness and operational simplicity. However, the conventional LFIA exhibits limited sensitivity and is susceptible to human variance for the result readout, impacting result interpretation. In this study, we introduced a novel one-step copper deposition-induced signal amplification lateral flow immunoassay (osa-LFIA) that markedly enhances the detection sensitivity for Staphylococcus aureus (protein A) and Pseudomonas aeruginosa (exotoxin A).

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Parameter quantification for oxygen transport in the human brain.

Comput Methods Programs Biomed

December 2024

Institute of Applied Mechanics, National Taiwan University, Taipei, Taiwan.

Background And Objective: Oxygen is carried to the brain by blood flow through generations of vessels across a wide range of length scales. This multi-scale nature of blood flow and oxygen transport poses challenges on investigating the mechanisms underlying both healthy and pathological states through imaging techniques alone. Recently, multi-scale models describing whole brain perfusion and oxygen transport have been developed.

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Article Synopsis
  • Improved battery performance is vital for high-power uses, but traditional electrode production methods can be complex, expensive, and harmful to the environment.
  • This study presents a new, eco-friendly microneedle technique inspired by acupuncture, utilizing cosmetic microneedle molds to create holes in lithium iron phosphate electrodes, which enhances electrolyte flow and ion transport.
  • Findings indicate that these microneedle-treated electrodes outperform standard electrodes in terms of rate performance and capacity, suggesting a potential for scaling up production for better battery technology.
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  • Green silver nanoparticles (AgNPs) were created using natural extracts and used for photocatalytic hydrogen production, promoting green energy and reducing reliance on fossil fuels.
  • These AgNPs enhanced the performance of g-CN nanosheets by broadening light absorption and improving electron transfer, leading to increased hydrogen production efficiency, particularly with AgNPs derived from coffee, green tea, and pomelo peels.
  • The study demonstrated that the combination of g-CN and AgNPs, especially from coffee, outperformed g-CN alone by efficiently producing hydrogen under low-intensity visible light, showcasing a significant step towards sustainable energy solutions.
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Microbubble-laden aerosols improve post-nasal aerosol penetration efficiency in a preterm neonate model.

Int J Pharm

December 2024

Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK. Electronic address:

Nebulized lung surfactant therapy has been a neonatology long-pursued goal. Nevertheless, many clinical trials have yet to show a clear clinical efficacy of nebulized surfactant, which, in part, is due to the technical challenges of delivering aerosols to the lungs of preterm neonates. The study aimed to test microbubbles for improving lung deposition in preterm neonates.

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Robot control in complex and unpredictable scenarios presents challenges such as adaptability, robustness, and human-robot interaction. These scenarios often require robots to perform tasks that involve unknown objects in unstructured environments with high levels of uncertainty. Traditional control methods, such as automatic control, may not be suitable due to their limited adaptability and reliance on prior knowledge.

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Smart hydrogels have recently garnered significant attention in the fields of actuators, human-machine interaction, and soft robotics. However, when constructing large-scale actuated systems, they usually exhibit limited actuation forces (≈2 kPa) and actuation speeds. Drawing inspiration from hairspring energy conversion mechanism, an elasticity-plasticity-controllable composite hydrogel (PCTA) with robust contraction capabilities is developed.

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Objectives: The aim of this study was to evaluate, in vitro, the load and type of failure of the sutured ventral abdominal fascia of cats with different sizes of suture material made of polydioxanone (PDX) (2-0, 3-0, 4-0, 5-0 USP).

Methods: A total of 32 samples of the ventral abdominal wall from 16 cadaveric cats were harvested using an hourglass-shaped template. The samples were sectioned longitudinally along the linea alba and then sutured together in a continuous pattern using four different randomly assigned sizes of pdx suture material (2-0, 3-0, 4-0, 5-0 USP).

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This study aims to fine-tune the plasma composition with a particular emphasis on reactive nitrogen species (RNS) including nitrogen dioxide (NO), dinitrogen pentoxide (NO), and nitrous oxide (NO), produced by a self-constructed cylindrical dielectric barrier discharge (CDBD). We demonstrated the effective manipulation of the plasma chemical profile by optimizing electrical properties, including the applied voltage and frequency, and by adjusting the nitrogen and oxygen ratios in the gas mixture. Additionally, quantification of these active species was achieved using Fourier transform infrared spectroscopy.

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Plant leaves have to deal with various environmental influences. While the mechanical properties of petiole and lamina are generally well studied, only few studies focused on the properties of the transition zone joining petiole and lamina. Especially in peltate leaves, characterised by the attachment of the petiole to the abaxial side of the lamina, the 3D leaf architecture imposes specific mechanical stresses on the petiole and petiole-lamina transition zone.

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Extracellular vesicles (EVs) are present in blood at much lower concentrations (5-6 orders of magnitude) compared to lipoprotein particles (LP). Because LP and EV overlap in size and density, isolating high-purity EVs is a significant challenge. While the current two-step sequential EV isolation process using size-expression chromatography (SEC) followed by a density gradient (DG) achieves high purity, the time-consuming ultracentrifugation (UC) step in DG hinders workflow efficiency.

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Understanding slow compression of frictional granular particles by network analysis.

Soft Matter

August 2024

Department of Mathematical Sciences, New Jersey Institute of Technology, University Heights, Newark, NJ 07102, USA.

We consider frictional granular packings exposed to quasi-static compression rates, with a focus on systems above the jamming transition. For frictionless packings, earlier work (S. Luding , , 2022, (9), 1868-1884) has uncovered that the system evolution/response involves smooth evolution phases, interrupted by fast transitions (events).

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In-silico analysis of hemodynamic indicators in idealized stented coronary arteries for varying stent indentation.

Comput Methods Biomech Biomed Engin

July 2024

Chair for Computational Analysis of Technical Systems (CATS), RWTH Aachen University, Aachen, Germany.

In this work, we investigate the effects of stent indentation on hemodynamic indicators in stented coronary arteries. Our aim is to assess in-silico risk factors for in-stent restenosis (ISR) and thrombosis after stent implantation. The proposed model is applied to an idealized artery with stent for four indentation percentages and three mesh refinements.

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To explore the creep characteristics of geomembrane under different tensile stresses, a series of creep tests were carried out on high-density polyethylene (HDPE) geomembrane specimens. For the interpretation and fitting of the experimental data, refined approximation functions were proposed. Particular attention was paid to the creep failure behavior under high tensile stresses, i.

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This study presents research into the unique method of depositing carbon layers onto processed surfaces, during finishing with abrasive films, on a global basis. The authors of this article are holders of the patent for this method. What makes this technology outstanding is that it integrates processes, whereby micro-finishing and the deposition of a carbon layer onto freshly exposed surface fragments is achieved simultaneously, in a single process.

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This study reports the synthesis of Cu micro-/nanosized particles through the polyol process. Cu particles were synthesized by reducing copper(ii) chloride in ethylene glycol (EG), polyvinylpyrrolidone (PVP), and potassium bromide (KBr) at low temperatures with or without the use of sodium borohydride (NaBH).

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Wild bird repulsion is critical in agriculture because it helps avoid agricultural food losses and mitigates the risk of avian influenza. Wild birds transmit avian influenza in poultry farms and thus cause large economic losses. In this study, we developed an automatic wild bird repellent system that is based on deep-learning-based wild bird detection and integrated with a laser rotation mechanism.

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For the first time, phytochemical constituents of the leaves of were investigated. One rare new 2,28-bidesmosidic lupane-type saponin, named heptaellipside A (), along with four other lupane-type analogs () were purified by combining differently chromatographic methods. All of the separated compounds () were communicated for the first time from .

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