Green synthesis of silver nanoparticles using Ocimum sanctum for efficient Congo red dye removal: a response surface methodology approach.

Synthetic dyes, such as Congo red (CR), pose serious threats to human health and aquatic ecosystems because of their carcinogenicity and resistance to degradation, necessitating the development of efficient and eco-friendly remediation strategies. In this study, silver nanoparticles (AgNPs) were synthesized via a green method using Ocimum sanctum (holy basil) leaf extract and applied for CR dye removal from aqueous solutions. The adsorption process was optimized using response surface methodology (RSM) based on Box-Behnken design (BBD), evaluating the influence of key parameters including pH, AgNP dosage, initial dye concentration, contact time, and temperature.

Biology and life tables of the predatory mite (Neoseiulus longispinosus) on different developmental stages of the two-spotted spider mite (Tetranychus urticae) on carnation (Dianthus caryophyllus) cultivars.

The phytoseiid mite, Neoseiulus longispinosus (Evans) is considered as one of the effective biological control agents against the tetranychid mites in the Indian subcontinent. This predator can be effectively utilized to manage the two-spotted spider mite, Tetranychus urticae Koch under protected conditions. Carnation holds a significantly important position as cut flower crop in India as well as throughout the world.

Unraveling biomolecular interactions: a comprehensive review of the electromobility shift assay.

The electromobility shift assay (EMSA) is a popular and productive molecular biology tool for studying protein-nucleic acid interactions. EMSA is a technique applied to the revelation of the binding dynamics of proteins, like transcription factors, to DNA or RNA. There are ample essential phases in the technique.

Harnessing CoO/AgMoO/CeO ternary nanocomposites for solar light-induced degradation of anthropogenic dye contaminants.

A CoO/AgMoO/CeOternary nanocomposites photocatalyst was successfully synthesized through a straightforward ethanol-assisted chemical method. Comprehensive characterization of its structural and optical properties was conducted using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Raman spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), UV-Vis diffuse reflectance spectroscopy (UV-DRS), and photoluminescence (PL) analysis. XRD analysis confirmed the presence of CoO, AgMoO and CeO in the ternary composite sample.

Technical note: reduction of a posteriorly dislocated humeral head via the anterior deltopectoral approach in a posterior fracture dislocation of the proximal humerus.

We aim to describe an approach for reducing the posteriorly dislocated humeral head through the rotator interval via a deltopectoral approach that is frequently utilized for internal fixation of proximal humerus fractures and fracture dislocations. The sheath of the long head of biceps (LHB) and the rotator interval capsule are opened till the glenoid; this enables access to the glenohumeral joint via the rotator interval. A long-handle Cobb elevator is introduced through the rotator interval and, under intraoperative imaging, advanced posteromedially to the dislocated humeral head.

An Efficient Fluorescent Probe Based on Triphenylimidazole End-Capped Diketopyrrolopyrrole for Selective Detection of CN and TFA Through On-Off-On Response.

A triphenyl-imidazole end-capped donor-acceptor type potential molecular probe 3 has been designed and synthesized. Probe 3 upon interaction with different classes of metal ions/anions and NPPs displayed high selectivity with CN anion (LOD = 20.42 nM) through fluorescence "turn-Off" response and a naked-eye sensitive visible color change.

A journey of leading a healthcare start-up in India: from the National Health Service to a corporate leadership culture.

Background: In 2021, Dr Kalra embraced an opportunity for a leadership role at a start-up healthcare organisation in India. This gave him an opportunity to adapt his National Health Service (NHS) leadership experience to the evolving Indian private healthcare landscape. This paper shares his lived experience as a National Medical Director and delves into the experiences and leadership insights he acquired during this.

Prevalence of vision impairment and refractive error in rural Nepalese children under five years of age.

Clinical Relevance: Good vision is critical for childhood development and education. Pre-school vision screening is important for early detection and treatment of visual problems, and prevention of life-long vision loss.

Background: The aim of this study was to determine the prevalence of vision impairment (VI) and refractive error (RE) in rural Nepalese children under five years of age.

A survey-based observational study on the prevalence and severity of dry eye symptoms in eye care professionals.

Clinical Relevance: Dry eye disease (DED) is associated with use of video screen based gadgets and long hours spent looking through microscopes. Use of 3D goggles to view 3D screens leads to eye strain and worsening of dry eye symptoms. It is important to identify and treat the symptoms in professions carrying a high risk of DED.

Tracing the possible origins of the clade 2.3.4.4b highly pathogenic avian influenza H5Nx viruses from India.

Highly pathogenic avian influenza (HPAI) clade 2.3.4.

Association of intraoperative end-tidal CO levels with postoperative outcomes: a patient-level analysis of two randomised clinical trials.

Background: The relationship between intraoperative end-tidal CO (etCO) levels and postoperative outcomes remains unclear. We conducted a post hoc analysis of two randomised trials in adults undergoing major surgery under general anaesthesia.

Methods: We re-analysed individual participant data comparing high or low positive end-expiratory pressure with low tidal volume intraoperative ventilation using a merged database derived from two randomised trials in non-obese (PROVHILO: ISRCTN70332574) and obese (PROBESE: NCT02148692) patients.

Clinical utility of bone marrow biopsy and significance of early diagnosis of Gaucher's disease.

Gaucher's disease (GD) is the most common lysosomal storage disorder inherited in an autosomal recessive pattern. It occurs due to a deficiency of the enzyme glucocerebrosidase owing to a mutation in the acid-β-glucosidase () gene resulting in accumulation of glucocerebrosides in lysosomes of cells. It presents with abdominal distension, hepatosplenomegaly, developmental delay, pancytopenia, neurological manifestations and bone diseases.

A large left ventricular sub-mitral thrombus in the absence of sub-mitral aneurysm in a patient with colorectal adenocarcinoma.

A left ventricular sub-mitral thrombus without an aneurysm is a previously unreported rare occurrence. We aim to bring attention to this finding in a case of colorectal adenocarcinoma.An early 60s-year-old female presented with bleeding per rectum, weight loss and fatigue and was found to have colorectal carcinoma with metastasis based on examination, imaging and biopsy findings.

Spontaneous thrombosis of vein of Galen malformation.

Vein of Galen malformation (VGM) is an uncommon vascular anomaly, with spontaneous thrombosis within it being exceedingly rare. This case report describes a paediatric patient in early adolescence who presented with a 15-day history of holocranial headache and vomiting. Examination revealed significant papilloedema, and imaging confirmed a thrombosed VGM causing upstream hydrocephalus.

Seizures and hypoparathyroidism post-thyroidectomy: Fahr's syndrome.

Fahr's syndrome is a rare neurological condition marked by unusual calcifications in the basal ganglia and other brain regions, often resulting from metabolic disorders, such as hypoparathyroidism. Secondary hypoparathyroidism, a frequent complication of total thyroidectomy, can lead to Fahr's syndrome, manifesting as movement disorders, seizures, psychiatric symptoms and indications of calcium deficiency. This case report discusses a woman in her mid-30s who developed Fahr's syndrome due to secondary hypoparathyroidism after total thyroidectomy.

Risk-field assessment for signalized intersections using surrogate safety measure.

Introduction: Traffic signals are the controlling devices aimed to reduce crossing conflicts at intersections. However, rear-end and lane-changing conflicts at signalized intersection approaches are a significant problem. This work aims to proactively assess and spatially map the safety and risk at signalized intersection approaches by field data collection and microsimulation modeling using PTV-VISSIM.

Investigating contributing factors to severe injuries in crashes involving motorized rickshaws in Pakistan.

Introduction: Motorized rickshaws are a common mode of urban transportation in many low and middle-income countries, particularly in South Asia (e.g., Pakistan and India).

Assessing health system preparedness from trends and time delays in the management of myocardial infarctions during the COVID-19 pandemic in India: a multicentre retrospective cohort study.

Objectives: This study aimed to analyse the number of myocardial infarction (MI) admissions during the COVID-19 lockdown periods of 2020 and 2021 (March 15th to June 15th) and compare them with corresponding pre-pandemic period in 2019. The study also evaluated changes in critical treatment intervals: onset to door (O2D), door to balloon (D2B) and door to needle (D2N) and assessed 30-day clinical outcomes. This study examined MI care trends in India during the COVID-19 lockdown period, irrespective of patients' COVID-19 infection status.

Molecular Insights of Phytohormone-Like Small Biomolecules for Microalgae-Mediated Heavy Metal Bioremediation.

Environmental sustainability is seriously threatened by the discharge of wastewater containing hazardous heavy metals (such as Cr, Cd, As, Hg, etc.). The utilization of microalgae has recently come to light as a viable, environmentally acceptable method for removing heavy metals from contaminated sites.

COMPARING THE EFFICACY OF VELSCOPE WITH VITAL STAINS IN THE DIAGNOSIS OF (COMMON)ORAL POTENTIALLY MALIGNANT DISORDERS AN OBSERVATIONAL STUDY.

Objective: Oral potentially malignant disorders (OPMDs) are a diverse group of oral mucosal lesions that carry an increased risk of malignant transformation. Although biopsy is the gold standard for the diagnosis of these lesions, early detection is crucial, emphasizing the need to introduce more reliable non-invasive screening modalities. The aim of the study was to compare the efficacy of VELscope and vital tissue staining techniques as screening tools in the detection of early dysplastic changes in OPMDS, such as oral leukoplakia (OL), oral lichen planus (OLP) & oral submucous fibrosis (OSMF) with histopathological confirmation.