3 results match your criteria: "Fraunhofer Research and Development Center for Marine and Cellular Biotechnology EMB[Affiliation]"
Axonal degeneration (AxD) is a pathological hallmark of many neurodegenerative diseases. Deciphering the morphological patterns of AxD will help to understand the underlying mechanisms and develop effective therapies. Here, we evaluated the progression of AxD in cortical neurons using a novel microfluidic device together with a deep learning tool that we developed for the enhanced-throughput analysis of AxD on microscopic images.
View Article and Find Full Text PDFEvaluation of the Effects of Fucoidans from Species and against Oxidative Stress and Iron-Dependent Cell Death.
Mar Drugs
September 2021
Department of Ophthalmology, University Medical Center, University of Kiel, Arnold-Heller-Str. 3, Haus 25, 24105 Kiel, Germany.
Article Synopsis
- Fucoidans are polysaccharides from brown seaweeds that may help protect against oxidative stress, particularly ferroptosis, linked to retinal and brain diseases.
- The study evaluated various fucoidan extracts' effectiveness in reducing cell death in specific retinal and neuronal cell lines, finding limited protective effects.
- Results suggest that the antioxidant properties of fucoidans vary by cell type and extraction methods, signaling a need for further research to understand their potential health benefits and mechanisms.
The potential of marine resources for retinal diseases: a systematic review of the molecular mechanisms.
Crit Rev Food Sci Nutr
September 2022
Department of Marine Biotechnology, Fraunhofer Research and Development Center for Marine and Cellular Biotechnology EMB, Lübeck, Germany.
We rely on vision more than on any other sense to obtain information about our environment. Hence, the loss or even impairment of vision profoundly affects our quality of life. Diet or food components have already demonstrated beneficial effects on the development of retinal diseases.
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