Unmasking Rarity: An Atypical Presentation of Lemierre's Syndrome.

Lemierre's syndrome (LS), otherwise known as postanginal sepsis, is a frequently overlooked condition characterized by septic thrombophlebitis of the internal jugular vein (IJV), usually caused by oropharyngeal infection. However, ear space (otogenic) infections are one of the atypical causes of LS and have been rarely reported. We present a case of a male in his 20s with a history of recurrent acute otitis media (RAOM) who presented with purulent ear discharge, fever, neck pain, and swelling for a week.

Modeling the Spatiotemporal Habitat Suitability Distributions of Cultural Keystone (Adey Abeba) Under Climate Change Scenarios in Ethiopia.

Bidens macroptera symbolizes the change of a season, marking the transition from the rainy season to autumn, heralding the new year for Ethiopians. Despite a general understanding of its geographic regions, significant gaps remain in identifying the habitat distribution and key predictor variables of Bidens macroptera through species distribution modeling (SDM) in the context of climate change. We developed an ensemble species distribution model using 2 statistical and 3 machine learning algorithms.

Retention of Vitamins A and D in Fortified Soybean Oil During Ethiopian Traditional Cooking and Shelf-Life Stability During Storage.

Vitamin A and vitamin D deficiencies continue to pose serious health challenges, especially in low- and middle-income countries like Ethiopia. One promising way to tackle this issue is by fortifying everyday foods-such as cooking oils-with essential nutrients to help improve the overall intake across communities. This study investigated the stbility of vitamins A and D in fortified soybean oil during common Ethiopian cooking practices and over time during storage.

Thrombosis in Brothers With Protein S Deficiency: Case Series.

Hereditary protein S deficiency is a rare thrombophilia that increases the risk of venous thromboembolism (VTE), including thrombosis in unusual sites. Early diagnosis, familial screening, and long-term anticoagulation are essential for preventing complications and improving outcomes.

Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP): A global effort to identify genetic factors in Alzheimer's disease.

Introduction: Alzheimer's disease (AD) remains a major neurocognitive disorder of global health significance. Globalizing ancestral diversity in AD genetics is essential to identify causal variants, improve diagnosis, and enable equitable therapeutic interventions across populations. The Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP) initiative addresses this by including African ancestry and Hispanic/Latinx (HL) ancestry populations.

Nutritional assessment of children admitted at Tikur Anbessa Specialized Hospital, School of Medicine, College of Health Sciences.

Objectives: This study aimed to assess the nutritional status of children aged 1 month to 14 years during admission and discharge at Tikur Anbesa Specialized Hospital, Addis Ababa, Ethiopia.

Methods: A prospective descriptive study design was employed, utilizing structured and nonstructured questionnaires to collect data. A total of 400 children, aged 1 month to 14 years, were included in the study.

Bleeding Duodenal Dieulafoy's Lesion in a Pediatric Patient From Ethiopia: A Case Report.

Dieulafoy's lesion, though rare in children, should be considered in cases of severe gastrointestinal bleeding. Early recognition and prompt endoscopic combination therapy with hemostatic clipping and adrenaline injection are essential for successful outcomes and preventing life-threatening complications.

Evaluation of Hypertension Care Services in 93 Ethiopian Public Healthcare Facilities From 2019 to 2023: A Quasi-Experimental Study.

Background And Aims: Hypertension is becoming a major public health issue in Ethiopia. However, there is limited comprehensive evidence on hypertension care, including service availability, utilization, and care quality. This study aimed to determine the effect of the NORAD-WHO-NCD intervention in improving the availability, utilization, and quality of hypertension care in public healthcare facilities.

COVID-19 Vaccine Hesitancy, Self-Reported Adverse Events, and Determinants Among Ethiopian Healthcare Professionals During COVID-19 Pandemic.

This nationwide cross-sectional online survey aimed to assess coronavirus disease 2019 (COVID-19) vaccine hesitancy, self-reported adverse events (SRAEs), and associated determinants among Ethiopian healthcare professionals (HCPs) during the pandemic (June 19-July 31, 2021). This survey collected data from 674 HCPs after the COVID-19 vaccine's first dose became available in Ethiopia. Hesitancy to the first and second vaccine doses was 45.

Impact of Fertilization on Antioxidant Activity, Microbiological Quality, and Sensory Attributes of Tomato ( L.) Cultivated in Ethiopia's Central Rift Valley.

Tomatoes, known for their antioxidant capacity, are mostly recommended by health professionals. Despite their nutritional significance, progress in enhancing their nutritional qualities and safety has been limited. This study evaluated the effects of compost-based (organic) and chemical-based (conventional) fertilization on the antioxidant activity, microbiological quality, and sensory attributes of four commonly cultivated tomato varieties (, , , and ) in Ethiopia's Central Rift Valley.

Incretin-Based Therapies in Alzheimer's and Parkinson's Disease: Advancing Neuroprotection With Dual and Triple Agonists-A Review.

Background: Alzheimer's disease (AD) and Parkinson's disease (PD) are progressive neurodegenerative disorders with significant cognitive and motor impairments, affecting millions globally. Current treatments offer limited efficacy, prompting the exploration of new therapeutic approaches.

Aim: To discuss the intricate relationship between incretin and insulin signaling pathways and their relevance to the pathogenesis and treatment of Alzheimer's and Parkinson's diseases.

Mitigation of Fungal Contamination in Vegetables: Key Factors From a Study in Debre Tabor, Ethiopia.

Fungal contamination in vegetables is a significant public health concern due to its potential to cause foodborne illnesses and affect food safety. This study assessed fungal contamination levels in commonly consumed vegetables in Debre Tabor City, Ethiopia, focusing on measuring mold and yeast loads and identifying factors influencing these contamination levels. A cross-sectional study was conducted involving the collection of vegetable samples from various markets in Debre Tabor City.

Characteristics and In-Hospital Outcomes of Patients With Septic Shock in the Adult Medical Intensive Care Unit of a Tertiary Hospital in Ethiopia: A Prospective Observational Study.

Background And Aims: Sepsis and septic shock are major healthcare problems, affecting millions of people around the world each year and claiming the lives of one-sixth to one-third of those affected. However, there is insufficient data on the characteristics and outcomes of septic shock patients in resource-limited settings. This study aimed to assess the characteristics and in-hospital outcomes of septic shock among patients admitted to the adult medical intensive care unit (ICU) of a tertiary hospital in Ethiopia.

Characterization of Microencapsulated Essential Oil Prepared by Spray and Freeze-Drying Using Gum Arabic as Carrier Material.

The process of microencapsulation is used to coat essential oils that are vulnerable to oxidation, dampness, UV light, and high temperatures. It serves to shield the active chemicals from the environment while boosting the core material's controlled release, stability, and solubility. This work used spray and freeze-drying procedures to microencapsulate essential oil extracted from () leaves using hydro distillation.

Factors associated with contraceptive use among women with epilepsy: A cross-sectional study.

Background: Epilepsy is the most common neurologic disorder globally. Women with epilepsy (WWE) have a special need for contraception and careful pregnancy planning. This study aimed to determine the utilization of modern contraceptive methods and associated factors among WWE at neurology clinics in Addis Ababa, Ethiopia.

Microbiologically Confirmed Primary Tubercular Breast Abscess in a Young Female: A Case Report.

Tuberculosis rarely affects the breast. This report presents a case of a microbiologically confirmed primary tubercular breast abscess in a young Ethiopian woman. A 26-year-old woman presented with left breast swelling and pain for 1 year.

Determining Body Composition-Based BMI Cut-Offs for Ethiopian Adults in Northwest Ethiopia: A Population-Based Cross-Sectional Study.

Background: Body mass index (BMI) is widely used as a population-level measure of obesity, given its robustness and inclusion in health surveys. However, for Ethiopians, the applicability of universally recognized anthropometric cutoffs may be inadequate. This study aimed to determine body composition-based BMI cutoffs for the healthy adult population of Ethiopia.

Exploring the Nutritional and Anti-Nutritional Composition of Traditionally Fermented From Widely Cultivated Enset () Landraces in Central Ethiopia.

Enset is a multipurpose perennial root crop primarily used as a staple food for over 25 million people in Ethiopia. Despite the existence of various landraces, little information is known about their nutritional profile. Thus, the aim of this study was to determine the nutritional and anti-nutritional contents of from the eight widely cultivated landraces.

Plummer-Vinson Syndrome With Coexistent Thyro-Cardiac Disease and Acute Decompensated Heart Failure: A Case Report.

Plummer-Vinson Syndrome (PVS) is a rare disorder characterized by the triad of dysphagia, iron-deficiency anemia, and esophageal webs. Limited data on its prevalence exist, with most information derived from case reports. We present the case of a 60-year-old woman with a 6-month history of a progressively enlarging anterior neck mass and worsening symptoms of heart failure, heat intolerance, and dysphagia.

Monkeypox: Prevention Strategies and Challenges: Updated Review.

Background And Aims: The mpox virus, sometimes known as MPXV, is the cause of the disease mpox. The Monkeypox virus is a different Poxviridae family member from the orthopoxvirus (OPXV) group. Clades I and II are the two varieties of the Monkeypox virus.

Clinical characteristics and outcomes of patients undergoing percutaneous coronary intervention at Gesund Cardiac and Medical Center, Addis Ababa, Ethiopia, 2024.

Introduction: Percutaneous coronary intervention (PCI) is a critical procedure for improving blood flow by alleviating arterial blockage. However, its availability in Ethiopia is limited because of insufficient resources, staff, and infrastructure.

Objective: To evaluate the clinical characteristics and outcomes of patients who underwent percutaneous coronary intervention at Gesund Cardiac and Medical Center in Addis Ababa, Ethiopia, in 2024.

Behind the Healing: Exploring the Psychological Battles of Kidney Transplant Patients: A Qualitative Insight.

Background And Aims: Kidney transplantation is widely regarded as the optimal treatment for end-stage renal disease, offering benefits like prolonged life expectancy, enhanced quality of life, and greater cost-effectiveness compared to dialysis. While dialysis imposes considerable restrictions on patients, including diminished independence, many of these challenges can be alleviated through successful transplantation. However, despite the physical advantages of kidney transplants, the psychological struggles faced by transplant recipients are often overlooked, particularly in Ethiopia.

Assessment of Human Papillomavirus Vaccine Knowledge and Attitudes Among Adolescent School Girls in Debre Berhan City, Ethiopia: A Community-Based Cross-Sectional Study.

Background And Aims: Chronic human papillomavirus (HPV) infections are the main cause of cervical carcinoma (CC). It has a significant worldwide disease burden and is the fourth most prevalent malignancy in women. Cervical cancer is the second most common cancer among Ethiopian women, causing an estimated 4884 deaths and 7095 new instances of diagnosis annually.

Effective Innovative Technologies and One Health Strategies in Mitigating Aflatoxin Contamination in Peanut Oil: A Systematic Review and Meta-Analysis.

Aflatoxin contamination in peanut oil poses significant health, agricultural, and environmental risks. This study assesses the effectiveness of advanced technologies and One Health strategies in mitigating these risks. Through systematic review and meta-analysis, we evaluate the effectiveness of integrated approaches.

Giardiasis: Report of a Case Refractory to Treatment.

Giardiasis, an intestinal infection caused by , remains a significant global health concern. Although standard treatments such as metronidazole are typically effective, there are increasing reports of treatment resistance, highlighting the need for alternative therapeutic strategies for which established guidelines do not exist. This case report illustrates the challenges in diagnosing and managing treatment-refractory giardiasis.