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Article Abstract
Objective: Identify psychosocial risk factors for non-adherence to medication following liver transplantation.
Methods: We used the Medication Level Variability Index (MLVI) for the assessment of adherence in 52 subjects selected for a pre-transplant liver procedure and monitored them for 6 months following transplantation. Patients were divided into exposed and non-exposed groups according to adherence, and each group was analyzed using psychosocial variables: demographic characteristics, quality of life, impulsivity, resilience, anxiety and depression.
Results: Patients with non-adherence had lower scores in the SF-36v2 domains and in the components of physical and mental health, with significant differences in the physical functioning (P=0.03) and physical health component (P=0.03) domains. In addition, non-adherent patients showed higher levels of impulsiveness (P=0.04) and 44.2% of the non-adherent patients being men (P=0.04).
Conclusion: Physical functioning and summary of the physical components of quality of life, impulsivity and male gender were associated with low adherence to medication.
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| http://dx.doi.org/10.1590/S0004-2803.24612025-012 | DOI Listing |
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