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Introduction: Physical activity level plays a role in modifying the likelihood of developing Alzheimer's disease and related dementias. However, little is known about how changes in housework affect cognitive function among US adults over the age of 65. This study investigates the correlation between changes in housework frequency and cognitive function over 10 years.
Methods: Data from 8141 adults aged ≥ 65 years in the Health and Retirement Study were analyzed, with changes in housework frequency categorized as "consistently high," "low to high," "high to low," and "consistently low" from 2008 to 2010. Cognitive function was measured from 2010 to 2018 using a composite score (range = 0-35), and mixed-effects linear regression models were fitted.
Results: Of 8141 participants (median age: 75 years [SD: 6.6] and 59.3% female), individuals who reported changes in housework frequency from high to low and consistently low were associated with an additional cognitive decline of 0.079 (95% CI, -0.117 to -0.042) and 0.090 (95% CI, -0.126 to -0.054), respectively, relative to those whose housework frequency remained consistently high. There was no statistically significant additional decline among adults reporting low to high frequency compared with those reporting consistently high housework frequency ( = -0.027; 95% CI, -0.074 to 0.019; = .252). This association was similar among women and men ( = .765) and was also similar among adults aged ≥ 80 years and those aged 65-79 years ( = .069).
Conclusion: Transitioning from low to high or maintaining consistently high housework engagement in later life was associated with a delay in cognitive decline, regardless of gender and age.
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http://dx.doi.org/10.7812/TPP/24.173 | DOI Listing |
Transplantation
September 2025
Department of Surgery, NYU Langone Health, New York, NY.
Background: Disparities in posttransplant outcomes persist and worsened during the COVID-19 pandemic, disproportionately affecting individuals with social risk factors. This study examined the total and residual (ie, direct) associations between individual- and neighborhood-level income and posttransplant outcomes among deceased donor kidney transplant (DDKT) and living donor kidney transplant recipients transplanted in the United States in 2020.
Methods: This retrospective cohort study linked Organ Procurement and Transplantation Network data with estimated individual annual income from LexisNexis and neighborhood median annual household income from the American Community Survey.
Vaccine
September 2025
Department of Epidemiology, Institute of Social Medicine, University of State of the Rio de Janeiro. 524 São Francisco Xavier St. Maracanã, Bloco E, 7th Floor, Rio de Janeiro - RJ, Cep 20550-013, Brazil. Electronic address:
Background: There is limited data on adult opinions toward school-based vaccination programs, which can supplement clinic-based strategies in the Brazilian public health system. Since 2016, vaccination rates among Brazilian children and adolescents have shown worrisome declines, remaining well below full coverage, including for more recently introduced COVID-19 vaccines. School vaccination programs are not commonly implemented or monitored in Brazil.
View Article and Find Full Text PDFVaccine
September 2025
Mérieux Foundation, 17 Rue Bourgelat, 69002 Lyon, France. Electronic address:
Introduction: Streptococcus pneumoniae is a major cause of lower respiratory infections, especially in children under 5 years old. While pneumococcal conjugate vaccines (PCVs) have reduced disease burden in many countries, data from low- and middle-income countries are still limited. The objective of this prospective, hospital-based, cross -sectional study was to measure the prevalence of pneumococcal colonization and identify circulating serotypes among children <5 years and their caregivers in Cambodia and India.
View Article and Find Full Text PDFPerm J
September 2025
Division of Hematology and Oncology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Introduction: Physical activity level plays a role in modifying the likelihood of developing Alzheimer's disease and related dementias. However, little is known about how changes in housework affect cognitive function among US adults over the age of 65. This study investigates the correlation between changes in housework frequency and cognitive function over 10 years.
View Article and Find Full Text PDFEnviron Res
September 2025
Department of Environmental Epidemiology, Institute for Risk Assessment Sciences (IRAS), Utrecht University, Utrecht, Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.
While studies have examined associations between air pollution and subjective long COVID outcomes such as fatigue and symptoms, no studies have focused on objective lung health measures. This study aimed to assess the impact of air pollution, examined through different exposure methods (exposures assigned via geospatial model, versus residential and personal measurements) on pulmonary function and radiological abnormalities in long COVID patients. We recruited 95 patients who attended a hospital outpatient clinic 3-6 months post-infection, during which pulmonary function was assessed via spirometry (FEV1,FVC,FEV1/FVC ratio) and diffusion capacity for carbon monoxide (DLCO), along with a chest CT.
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