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http://dx.doi.org/10.1111/jdv.70054 | DOI Listing |
J Eur Acad Dermatol Venereol
September 2025
School of Medicine, College of Medicine, Chung Shan Medical University, Taichung, Taiwan.
JAMA Dermatol
September 2025
Univ Rennes, CHU Rennes, Inserm, EHESP, Irset (Institut de Recherche en 13 Santé, Environnement et Travail)-UMR_S 1085, Rennes, France.
Importance: The cardiovascular impact of biologics used in psoriasis is not fully understood. Several studies have suggested that the inhibition of the T-helper 17 cell pathway could lead to the destabilization of atherosclerotic plaques, leading to major adverse cardiovascular events (MACEs).
Objective: To assess whether the initiation of interleukin (IL)-17(R)A inhibitors triggers MACEs.
Sci Rep
August 2025
Hormones department, Medical Research and clinical studies institute, National Research Centre, Dokki, Cairo, 12622, Egypt.
Psoriasis is a chronic skin disorder with significant individual and societal impacts. Current therapies often lack efficacy, are costly, or cause side effects, necessitating new treatments. This study explores regenerative therapies-exosomes, mesenchymal stem cells (MSCs), epigallocatechin-3-gallate nanoparticles (EGN), and EGN-loaded exosomes (EGN-Exo)-in regulating psoriasis-related markers (IL-6, IL-4, Bcl-2, Bax, NF-κB, CDC25B).
View Article and Find Full Text PDFFront Med (Lausanne)
July 2025
Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland.
Introduction: Despite advancements in treatment, unmet needs persist for patients with plaque psoriasis (PSO). This study characterized PSO patients who were initiating or switching biologic medications, with or without prior biologic use, and highlighted the unmet needs due to medication switches and concomitant treatments. The impact of biologic therapy initiation was assessed through changes in healthcare resource utilization (HCRU), sick leave, and disability pensions.
View Article and Find Full Text PDFActa Dermatovenerol Croat
November 2024
Constantin A. Dasanu, Eisenhower Lucy Curci Cancer Center, 39000 Bob Hope Drive, Rancho Mirage, United States;
Familial benign chronic pemphigus, also known as Hailey-Hailey disease, was first described by the Hailey brothers in 1939 (1). It represents a chronic autosomal-dominant genetic skin disorder with incomplete penetrance, usually diagnosed in children and young adults. As a result, family history of this disorder can be elicited in only about 66% of patients.
View Article and Find Full Text PDF