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http://dx.doi.org/10.1016/j.scib.2025.08.030 | DOI Listing |
Nanoscale
September 2025
Institute of Health Innovation & Technology, National University of Singapore, Singapore, 117599, Singapore.
The rapid increase in multidrug-resistant (MDR) bacteria and biofilm-associated infections has intensified the global need for innovative antimicrobial strategies. Phage therapy offers promising precision against MDR pathogens by utilizing the natural ability of phages to specifically infect and lyse bacteria. However, their clinical application is hampered by challenges such as narrow host range, immune clearance and limited efficacy within biofilms.
View Article and Find Full Text PDFBiotechnol J
September 2025
Department of Molecular Biosciences and Bioengineering, University of Hawai'i at Mānoa, Honolulu, Hawai'i, USA.
CRISPR technologies are rapidly transforming agriculture by enabling precise and programmable modifications across a wide range of organisms. This review provides an overview of CRISPR applications in crops, livestock, aquaculture, and microbial systems, highlighting key advances in sustainable agriculture. In crops, CRISPR has accelerated the improvement of traits such as drought tolerance, nutrient efficiency, and pathogen resistance.
View Article and Find Full Text PDFExpert Rev Med Devices
September 2025
Department of Physical Medicine and Rehabilitation, Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Rae Bareli Road, Lucknow, Uttar Pradesh, INDIA 226014.
Introduction: The World Health Organization (WHO) reported in 2023 that approximately 1.3 billion people, or 16% of the global population, are living with a disability. Among these, locomotor disabilities constitute a significant portion, underscoring the urgent need for devices that enhance mobility and support daily living.
View Article and Find Full Text PDFBiotechnol J
September 2025
Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education, Yangzhou University, Yangzhou, China.
Vaccines are pivotal in mitigating infectious diseases by reducing infection rates, severity, and mortality. Plant-derived vaccines-engineered to express antigens in plants, offer distinctive advantages, including cost-efficient production, enhanced biosafety profiles, superior thermal stability, and simplified logistics. Recent advances in plant biotechnology have enabled the large-scale production of plant-based vaccines, positioning them as a viable and transformative alternative to conventional vaccine platforms.
View Article and Find Full Text PDFEndocrinol Diabetes Metab
September 2025
Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Objective(s): To evaluate the quality, reliability and accuracy of hyperthyroidism-related content on TikTok using validated assessment tools.
Methods: We systematically searched TikTok for 'hyperthyroid' and 'high thyroid', analysing 115 videos after exclusions. Two independent researchers assessed videos using the Global Quality Scale (GQS, range 0-5) for overall content quality, the modified DISCERN (mDISCERN, range 0-5) for reliability and the Accuracy in Digital Information (ANDI, range 0-4) tool for factual correctness.