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Cancer is a significant global health challenge with a high mortality rate. Developing efficient methods for diagnosing cancer in its early stages helps improve the chances of successful treatment. Moreover, integrating therapeutic methods with diagnostic and imaging techniques offers a promising strategy for achieving more precise treatment outcomes. The MIL-n series of metal-organic frameworks (MOFs), with several desirable properties, such as large surface area, appropriate stability, high porosity, and biocompatibility, are promising candidates for the preparation of applicable platforms for cancer diagnosis and efficient treatment. In this review, we will introduce the structural features of the well-known and widely used MILs in cancer research. Next, some reported sensors based on MILs will be described. Then, the application of MILs in combining cancer imaging and therapy will be summarized. Finally, we discuss challenges and future directions in the application of MILs for cancer diagnosis and theranostics. Through this review, we aim to highlight the potential of MILs in cancer research.
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http://dx.doi.org/10.1021/acsami.5c07263 | DOI Listing |
ACS Appl Mater Interfaces
September 2025
School of Chemistry, College of Science, University of Tehran, Tehran 14155-6455, Iran.
Cancer is a significant global health challenge with a high mortality rate. Developing efficient methods for diagnosing cancer in its early stages helps improve the chances of successful treatment. Moreover, integrating therapeutic methods with diagnostic and imaging techniques offers a promising strategy for achieving more precise treatment outcomes.
View Article and Find Full Text PDFInt J Surg Protoc
September 2025
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Introduction: Minimally invasive liver surgery (MILS), such as laparoscopic and robotic hepatectomy, has been developed and is an effective alternative to traditional open hepatectomy. Although surgical techniques and postoperative management have improved, many institutions continue to perform routine postoperative abdominal drainage. In open hepatectomy, abdominal drainage after uncomplicated hepatectomy increases overall and wound-related complications without a reduction in the risk of intra-abdominal fluid collections that require intervention.
View Article and Find Full Text PDFJ Surg Res
August 2025
Esophageal Surgery Unit, Surgery Department, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain; Universitat de Barcelona (UB), Barcelona, Spain.
Introduction: Gastric ischemic conditioning (GIC) before Ivor Lewis esophagectomy for cancer is associated with improved short-term outcomes, reducing the incidence and severity of anastomotic leakage (AL). The aim of this study was to explore the impact of GIC on long-term outcomes after esophageal surgery.
Materials And Methods: This randomized, single-center, controlled, parallel-group, pilot clinical trial included two groups: (1) GIC before Ivor Lewis esophagectomy and (2) surgery alone (SA).
Transl Oncol
October 2025
Department of Hematology-Oncology, Chonnam National University Hwasun Hospital and Chonnam National University Medical School, Hwasun, Jeollanamdo, Republic of Korea; Research Center for Cancer Immunotherapy, Chonnam National University Hwasun Hospital, Hwasun, Jeollanamdo, Republic of Korea; Vaxcel
Adoptive immunotherapy represents a promising treatment for multiple myeloma (MM), relying on the availability of sustainable tumor-specific cytotoxic T cells. This study generated potent ex vivo expanded and activated marrow-infiltrating lymphocytes (eMILs) from MM patients and evaluated their immunologic characteristics and cytotoxic potential. MILs were expanded using anti-CD3/CD28 beads in the presence of IL-2, IL-7, and IL-15.
View Article and Find Full Text PDFBMC Psychol
July 2025
Nursing Department, Shanghai Lung Hospital affiliated to Tongji University, Shanghai200433, China.
Objective: To explore the mediating effect of dyadic coping in the relationship between family functioning and meaning in life in patients with advanced lung cancer and to provide reference for developing intervention studies to improve meaning in life.
Methods: From April to August 2023, 300 inpatients in the oncology department of a Shanghai tertiary hospital were selected by convenience sampling method. The general data questionnaire, Dyadic Coping Inventory (DCI), Family Assessment Device (FAD) and Meaning in Life Scale for Advanced Cancer Patients (MiLs) were investigated.