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http://dx.doi.org/10.1007/s44313-025-00103-4 | DOI Listing |
Blood Res
September 2025
Department of Laboratory Medicine, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.
J Orthop Sports Med
July 2025
Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, 91766, USA.
Venous thromboembolism (VTE), a term encompassing both deep vein thrombosis (DVT) and pulmonary embolism (PE), remains a leading cause of mortality following total hip arthroplasty (THA) and total knee arthroplasty (TKA). Optimizing thromboprophylaxis, or the prevention of VTE after surgery, is becoming increasingly critical as the demand and frequency of total joint arthroplasty rises globally. This review covers the current literature on the risk factors, detection, and prevention of VTE in patients undergoing THA and TKA.
View Article and Find Full Text PDFBackground: Non-vitamin K antagonist oral anticoagulants (NOACs) increase the risk of bleeding during invasive procedures such as bronchoscopy. To mitigate this risk, NOACs are typically held before bronchoscopy. Current guidelines for discontinuing NOACs are based on drug half-lives and recommendations from similar invasive procedures.
View Article and Find Full Text PDFDiseases
August 2025
Programa de Especialización en Medicina Interna, Facultad de Salud, Universidad Santiago de Cali, Cali 5183000, Colombia.
Colorectal cancer (CRC) most commonly metastasizes to the liver and lungs; however, synchronous metastases to pelvic structures such as the vagina and urethra are extremely rare, posing a significant diagnostic and therapeutic challenge. This report describes an unusual case of sigmoid colon adenocarcinoma with synchronous metastases to the vagina and urethra, highlighting its diagnostic evaluation and the value of a multidisciplinary approach. A 59-year-old woman with a history of deep vein thrombosis treated with apixaban presented with chronic constipation and pelvic bleeding.
View Article and Find Full Text PDFJpn Dent Sci Rev
December 2025
Department of Stomatology, Shengjing Hospital of China Medical University, 36 Sanhao Street, Heping District, Shenyang 110004, China.
Objective: The aim of the present study was to assess and compare the bleeding risks in patients undergoing dentoalveolar surgery who were on uninterrupted therapy with direct oral anticoagulants (DOACs) or vitamin K antagonists (VKAs).
Methods: Electronic database searches were performed in PubMed, Embase, Web of Science, and CENTRAL through 28 September 2024, following PICOS criteria. Two reviewers independently performed literature screening, data extraction, and assessed the risk of bias.