Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Metasurfaces provide an ideal platform for optical sensing because they produce strong light-field confinement and enhancement over extended regions that allow us to identify deep-subwavelength layers of organic and inorganic molecules. However, the requirement of using external light sources involves bulky equipment that hinders point-of-care applications. Here we introduce a plasmonic sensor with an embedded source of light provided by quantum tunnel junctions. An optically resonant, doubly periodic nanowire metasurface serves as a top contact for the junction and provides extremely uniform emission over large areas, amplified by plasmonic nanoantenna modes that simultaneously enhance the spectral and refractive index sensitivity. As a proof of concept, we demonstrate spatially resolved refractometric sensing of nanometre-thick polymer and biomolecule coatings. Our results open exciting prospects based on a disruptive platform for integrated electro-optical biosensors.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411226 | PMC |
| http://dx.doi.org/10.1038/s41566-025-01708-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Colloidal gold technology in viral diagnostics: Recent innovations, clinical applications, and future perspectives.
Virology
September 2025
Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi, Xinjiang, China. Electronic address:
Colloidal gold technology has revolutionized viral diagnostics through its rapid, cost-effective, and user-friendly applications, particularly in point-of-care testing (POCT). This review synthesizes recent advancements, focusing on its role in detecting respiratory viruses, hepatitis viruses, and emerging pathogens. The technology leverages the unique optical and physicochemical properties of gold nanoparticles (AuNPs), including localized surface plasmon resonance (LSPR) and high surface-to-volume ratios, to achieve rapid antigen-antibody recognition with visual readouts within 15 min.
View Article and Find Full Text PDFWearable sensors for animal health and wellness monitoring.
Prog Mol Biol Transl Sci
September 2025
Nanobiology and Nanozymology Research Laboratory, National Institute of Animal Biotechnology (NIAB), Opposite Journalist Colony, Near Gowlidoddy, Hyderabad, Telangana, India; Regional Centre for Biotechnology (RCB), Faridabad, Haryana, India. Electronic address:
Biosensors are rapidly emerging as a key tool in animal health management, therefore, gaining a significant recognition in the global market. Wearable sensors, integrated with advanced biosensing technologies, provide highly specialized devices for measuring both individual and multiple physiological parameters of animals, as well as monitoring their environment. These sensors are not only precise and sensitive but also reliable, user-friendly, and capable of accelerating the monitoring process.
View Article and Find Full Text PDFPlasmonic biosensor enabled by resonant quantum tunnelling.
Nat Photonics
June 2025
Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Metasurfaces provide an ideal platform for optical sensing because they produce strong light-field confinement and enhancement over extended regions that allow us to identify deep-subwavelength layers of organic and inorganic molecules. However, the requirement of using external light sources involves bulky equipment that hinders point-of-care applications. Here we introduce a plasmonic sensor with an embedded source of light provided by quantum tunnel junctions.
View Article and Find Full Text PDFFacile Synthesis of Designer Shape-Defined Mesoporous Metal Nanoenzymes as Therapeutics for Diseases Involving Excessive Oxidative Stress.
Biomater Res
September 2025
Laboratory of Medical Imaging, The First People's Hospital of Zhenjiang, Zhenjiang 212001, P. R. China.
Mesoporous metal nanomaterials (MMNs) have gained interest in biomedicine for their unique properties, but their potential is limited by the predominance of spherical shapes and the neglect of morphological effects on biological activity, which hinders the reasonable evaluation of morphology-dependent enzyme-like activities and biological behaviors and its further biomedical applications. It is therefore imperative to find an effective and facile method to design and prepare MMNs with novel, well-defined morphologies. Herein, we fabricated 3 mesoporous platinum nanoenzymes including sphere, rod, and bipyramid topologies [Au@mesoPt sphere, Au@mesoPt rod, and Au@mesoPt bipyramid nanoparticles (NPs), respectively] via a facile atomic layer deposition method using gold NPs (Au NPs) as the templated cores and Pluronic F127 as a structure-directing agent.
View Article and Find Full Text PDFAmplification-free CRISPR/Cas12a biosensor integrating AuNPs-mediated surface plasmon resonance for human papillomavirus detection and genotyping.
Biosens Bioelectron
September 2025
Materials Artificial Intelligence Center, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China. Electronic address:
Screening for high-risk human papillomavirus (hrHPV) infection is essential for cervical cancer prevention. However, developing a simple, portable, and low-cost hrHPV genotyping method remains challenging, particularly in resource-limited settings. Herein, we present an innovative amplification-free, point-of-care hrHPV genotyping platform integrating CRISPR/Cas12a with alkaline phosphatase (ALP)-mediated surface plasmon effect.
View Article and Find Full Text PDF