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Purpose: Hatzenbuehler's psychological mediation framework proposes that difficulties in emotion regulation (ER), which are driven in part by excess exposure to stigma-related experiences, contribute to sexual orientation-related mental health disparities. However, existing research on the framework has largely focused on a small number of ER variables in non-probability samples.
Methods: To address these limitations, we examined whether a large complement of ER components mediates the prospective association between sexual minority status and depressive symptoms, using longitudinal data from a population-based sample of 1,208 Swedish young adults (aged 18-35). Data were collected in 2020 (ER, depressive symptoms) and 2021 (depressive symptoms). Participants completed 12 measures of ER, spanning a diverse array of ER constructs (e.g., emotional awareness, cognitive reappraisal, access to ER strategies).
Results: Sexual minorities exhibited significantly more ER difficulties on nine out of the 12 ER components, and higher depressive symptoms, compared to heterosexuals. Eight of the 12 ER components independently mediated the association between sexual minority status and increases in depressive symptoms one year later, and two components (brooding rumination, difficulty identifying positive emotions) mediated this relationship when all 12 ER components were entered into the model simultaneously.
Conclusion: These findings provide evidence from a population-based, longitudinal study that a wide range of ER factors underlie sexual orientation-related disparities in depressive symptoms during a developmental period of heightened risk.
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http://dx.doi.org/10.1007/s00127-025-02974-5 | DOI Listing |
JAMA Netw Open
September 2025
Department of Social Epidemiology, Graduate School of Medicine and School of Public Health, Kyoto University, Kyoto, Japan.
Importance: Previous studies have suggested that social participation helps prevent depression among older adults. However, evidence is lacking about whether the preventive benefits vary among individuals and who would benefit most.
Objective: To examine the sociodemographic, behavioral, and health-related heterogeneity in the association between social participation and depressive symptoms among older adults and to identify the individual characteristics among older adults expected to benefit the most from social participation.
Child Psychiatry Hum Dev
September 2025
Department of Psychology, University of California, Los Angeles, CA, USA.
Youth anxiety and depression are rising rapidly worldwide, highlighting the need for efficient school-based assessment tools across sociocultural contexts. The Revised Child Anxiety and Depression Scale (RCADS) is one of the most widely used screening measures, with demonstrated cross-cultural applicability. However, its psychometric properties have rarely been evaluated in Chinese populations.
View Article and Find Full Text PDFEnviron Sci Process Impacts
September 2025
NMPA Key Laboratory for Safety Evaluation of Cosmetics, Guangdong Provincial Key Laboratory of Tropical Disease Research, Department of Toxicology, School of Public Health, Southern Medical University, 1023-1063 Shatai Nan Road, Guangzhou 510515, China.
Triclosan (TCS) has raised concerns due to its widespread use and potential neuroendocrine toxicity. However, its neurological effects and the interplay between TCS-induced sex hormone disruption and neurological outcomes in adults remain largely unexplored. Herein, we analyzed data from 2717 adults in the 2011-2014 National Health and Nutrition Examination Survey, employing logistic regression, restricted cubic spline, and mediation analyses to investigate the association between TCS exposure and neurological outcomes.
View Article and Find Full Text PDFAging Ment Health
September 2025
Department of Psychology, University of California, Irvine, CA, USA.
Objectives: Being socially integrated is vital to emotional well-being, partly because social connections provide purpose. Nevertheless, fewer have explored purpose in life as a potential mechanism linking social activity variety, one of the indicators of social integration, to mental health outcomes. This study examined purpose in life as a mediator in the relationship between earlier social activity variety and later depressive symptoms among U.
View Article and Find Full Text PDF