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| http://dx.doi.org/10.1016/j.cgh.2025.08.026 | DOI Listing |
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Warfarin is a widely used vitamin K antagonist (VKA) with known pleiotropic effects beyond anticoagulation. Preclinical and case-control evidence suggests that warfarin may affect hematopoiesis, but longitudinal human evidence is lacking. To explore this potential effect, we conducted a post-hoc analysis of participants in the Hokusai-VTE and ENGAGE AF-TIMI 48 trials, which randomized patients to warfarin or the direct oral anticoagulant edoxaban with routine laboratory testing at predefined follow-up visits.
View Article and Find Full Text PDFThe effect of aromatherapy massage with peppermint oil on functional impairments in patients with knee osteoarthritis.
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Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran. Electronic address:
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Center for Healthy Minds and Department of Counseling Psychology, University of Wisconsin-Madison, Madison, WI, United States.
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View Article and Find Full Text PDFAllogeneic hematopoietic stem cell transplantation in germline DDX41 mutated patients with myeloid malignancies.
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Germline DDX41 mutations (DDX41mut) are identified in approximately 5% of myeloid malignancies with excess of blasts, representing a distinct MDS/AML entity. The disease is associated with better outcomes compared to DDX41 wild-type (DDX41WT), but patients who do not undergo allogeneic hematopoietic stem cell transplantation (HSCT) may experience late relapse. Due to the recent identification of DDX41mut, data on post-HSCT outcomes remain limited.
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