Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: Recent studies demonstrated associations between hematological parameters and indices (HPI) obtained from full blood count (FBC) collected on the first day of life (D1) and the occurrence of intraventricular hemorrhage (IVH) in premature infants. Our objective was to evaluate the association between HPI obtained from the FBC of D1 and the occurrence of IVH in premature infants, to assess whether these can be used as prognostic markers.
Methods: This is a retrospective study, including preterm infants with gestational age below 30 weeks. A statistical analysis compared two groups of infants, with and without IVH.
Results: A total of 206 infants were included, 86 (41.7%) in the IVH group and 120 (58.3%) in the no-IVH group. The univariate analysis found that red blood cells (P = 0.018), hemoglobin (P < 0.001), and hematocrit (P = 0.001) were significantly lower in the IVH group. Multivariate analysis by logistic regression adjusted to gestational age and birth weight revealed no significant associations between HPI of D1 and the occurrence of IVH. An analysis in the subgroup of patients with IVH-3 (severe IVH) did not reveal an association between HPI and IVH-3. An association between bronchopulmonary dysplasia and IVH (all grades) was found (P = 0.016).
Conclusions: Our results demonstrate that HPI from FBC collected on D1 are not associated with the occurrence of IVH and therefore cannot be used as predictors of IVH in extremely premature infants.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.pediatrneurol.2025.08.007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Corrigendum to "Effectiveness of an oral-motor intervention for premature infants: Feeding and maternal self-efficacy" [Early Human Development 210 (2025) 106382].
Early Hum Dev
September 2025
School of Occupational Therapy, Faculty of Medicine, Hebrew University of Jerusalem, Israel.
Metataxonomic and bacterial culture studies of breast milk microbiota in mothers of premature infants: factors influencing its bacterial composition and diversity.
J Nutr
September 2025
Université Paris-Saclay, CEA, Centre National de Recherche en Génomique Humaine (CNRGH), 91057 Evry, France. Electronic address:
Background: Breast milk represents the optimal feeding strategy for newborns, supporting not only nutrition but also the establishment of a unique microbiota. The bacterial composition and diversity of this microbiota are shaped by various maternal and infant-related factors.
Objectives: This single-center prospective study aimed to examine the breast milk microbiota and determine the maternal and infant-related factors influencing its composition and diversity over the time.
Corynebacterium amycolatum: an underestimated pathogen in early-onset neonatal sepsis-a case report.
BMC Infect Dis
September 2025
Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, No.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, P.R. China.
Background: Early-onset neonatal sepsis (EOS) is a critical condition primarily caused by maternal-fetal transmission of bacterial pathogens during delivery, with Escherichia coli and Group B Streptococcus being the most prevalent. However, neonatal sepsis can also involve other rare bacteria, including Corynebacterium amycolatum, which was first described in 1988 and is widely recognized as an emerging pathogen in infectious diseases.
Case Presentation: A male infant was admitted to the neonatal intensive care unit (NICU) due to premature birth and tachypnea.
Risk factors for moderate/severe bronchopulmonary dysplasia: A retrospective cohort study including results of an accurate assessment of intra-uterine microbes.
J Reprod Immunol
September 2025
University of Toyama, 3190 Gofuku, Toyama-shi, Toyama 930-8555, Japan. Electronic address:
A highly sensitive PCR method developed in our university accurately identifies the presence or absence of intra-uterine (IU) microbes without false positive results. With the inclusion of the results of an accurate assessment of IU microbes, risk factors for the development of moderate/severe bronchopulmonary dysplasia (BPD), a chronic lung disease that affects premature infants who require prolonged oxygen therapy or medical ventilation, were examined in 107 spontaneous preterm neonates. Perinatal risk factors were compared between cases of moderate/severe BPD (N = 49) and mild/non-BPD (N = 58).
View Article and Find Full Text PDFHematological Parameters at Birth Fail to Predict Intraventricular Hemorrhage in Very Preterm Infants.
Pediatr Neurol
August 2025
Department of Neonatology, Centro Hospitalar e Universitário de São João, Porto, Portugal. Electronic address:
Background: Recent studies demonstrated associations between hematological parameters and indices (HPI) obtained from full blood count (FBC) collected on the first day of life (D1) and the occurrence of intraventricular hemorrhage (IVH) in premature infants. Our objective was to evaluate the association between HPI obtained from the FBC of D1 and the occurrence of IVH in premature infants, to assess whether these can be used as prognostic markers.
Methods: This is a retrospective study, including preterm infants with gestational age below 30 weeks.