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http://dx.doi.org/10.1016/j.clon.2025.103927 | DOI Listing |
J Urban Health
September 2025
School of Architecture and Design, Harbin Institute of Technology, Harbin, 150001, China.
Street-level environments play a vital role in children's development by promoting their physical activity, cognitive growth, and overall development. This study systematically reviews the measurement tools available to assess street environments according to children's needs. This systematic review was conducted according to the PRISMA-COSMIN guidelines.
View Article and Find Full Text PDFJ Pediatr Hematol Oncol
September 2025
Division of Pediatric Hematology/Oncology/Blood and Marrow Transplantation, Medical College of Wisconsin.
Background: While pegylated Escherichia coli asparaginase (PEG) is an integral component of leukemia and lymphoma treatment, hypersensitivity reactions (HSR) remain a common adverse event, often resulting in adjustments to the treatment regimen, increasing the burden on patients and families. HSR to asparaginase often indicates a transition to Erwinia asparaginase (ERW), which requires patients to return to the hospital 6 times for subcutaneous injections to replace one dose of IV PEG. Previous trials have demonstrated rates of HSR to pegylated E.
View Article and Find Full Text PDFBr J Dermatol
September 2025
National Disease Registration Service, Data and Analytics, NHS England, Leeds, UK.
Introduction: Skin cancers primarily affect people of White ethnicity and lighter skin tones, but people of other ethnicities may face diagnostic delays and experience higher mortality, reflecting existing inequities in healthcare. This is the first study showing incidence data from the National Disease Registration Service (NDRS) cancer registry in England for skin cancers stratified by the seven broad ethnic groups.
Methods: We used data from NDRS from 2013-20 to analyse melanoma, acral lentiginous melanoma (ALM), basal cell carcinoma (BCC), cutaneous squamous cell carcinoma (cSCC), cutaneous T-cell lymphoma (CTCL), and Kaposi sarcoma (KS).
Br J Haematol
September 2025
Department of Haematology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
In allogeneic haematopoietic stem cell transplantation (HSCT), important clinical decisions depend upon assessment of chimerism, including immunosuppressant dosing and donor lymphocyte infusions (DLI), which in turn can have major impacts on disease control, graft-versus-host disease (GVHD), immunity and ultimately patient survival. There is a complex range of clinical and laboratory procedural considerations including methodology of testing, types of cell subset selection, frequency of testing, urgency of turnaround times (TATs), interplay with measurable residual disease (MRD) monitoring and duration of testing post-transplant. These aspects are routinely adapted according to disease indication, patient characteristics, donor source and intensity of transplant technique.
View Article and Find Full Text PDFBasic Clin Androl
September 2025
Department of Urology, University Hospital Southampton, Southampton, UK.
Background: To compare surgical and long-term patient-reported outcomes (PRO) between excisional (Nesbit) and incisional (Yachia) corporoplasty for correction of uncomplicated Peyronie's-related penile curvature in a large, single-surgeon cohort. A retrospective audit identified men who underwent Nesbit or Yachia corporoplasty (2015-2021). Operative data was extracted from records.
View Article and Find Full Text PDF