Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Obesity significantly impacts the health and economy of modern society, and the prevention and treatment of obesity is a key focus of social research. The main reason for obesity is the excessive accumulation of body fat due to metabolic dysfunction, which may result in atherosclerosis, insulin resistance and abnormal lipid metabolism. So far, a number of mechanisms of intestinal flora and plant extracts have been found and applied to the treatment of obesity. However, because of the complexity of gut microbiota composition, it is still not clear which microbiota has a direct relationship with obesity. Curcumin (CUR) has a long-standing and important position in traditional Chinese medicine (TCM). It is a polyphenolic compound derived from the rhizome of . CUR has been widely studied in recent years for its multiple biological activities. In addition to its anti-inflammatory and antioxidant properties, CUR also shows potential in anti-cancer, anti-microbial, and neuroprotective effects. This review aims to systematically synthesize the current evidence on the effects and mechanisms of CUR targeting gut microbiota in obesity treatment, analyze the progress of CUR research in fat reduction and weight loss, and specifically clarify its role in modulating gut microbiota to exert both anti-obesity and anti-hyperlipidemic effects. By doing so, we seek to illuminate the intricate relationship between CUR, gut microbiota, and obesity with associated hyperlipidemia.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406307 | PMC |
| http://dx.doi.org/10.3389/fmicb.2025.1625098 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Targeting the gut-liver axis with dietary polyphenols to ameliorate metabolic dysfunction-associated steatotic liver disease: advances in molecular mechanisms.
Crit Rev Food Sci Nutr
September 2025
Hunan Key Laboratory of Deep Processing and Quality Control of Cereals and Oils, State Key Laboratory of Utilization of Woody Oil Resource, College of Food Science and Engineering, Central South University of Forestry and Technology, Changsha, Hunan, China.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a condition that results from metabolic disorders. In addition to genetic factors, irregular and high-energy diets may also significantly contribute to its pathogenesis. Dietary habits can profoundly alter the composition of gut microbiota and metabolites.
View Article and Find Full Text PDFDifferent sources and dosages of zinc oxide and copper influence growth performance and intestinal health of post-weaning piglets.
J Anim Sci
September 2025
Department of Animal Sciences, Laval University, Québec, QC G1V 0A6, Canada.
In pig production, weaning is a critical period where piglets face several environmental stressors. This transition leads to a significant growth reduction and can result in digestive disorders, including diarrhea. To formulate a feed that meets zinc (Zn) and copper (Cu) requirements during the weaning period while minimizing their release into the environment, it became evident that a more bioavailable micro-mineral supplement is necessary.
View Article and Find Full Text PDFEffectiveness of Medical Nutrition Therapy in the Management of Patients with Obesity and Endometriosis: from the Mediterranean Diet To the Ketogenic Diet, Through Supplementation. The Role of the Nutritionist in Clinical Management.
Curr Obes Rep
September 2025
Department of Medicine, Division of Endocrinology, University of Arizona, Tucson, AZ, USA.
Purpose Of The Review: This review aimed to summarize current evidence on the effectiveness of medical nutrition therapy (MNT) in the management of obesity and endometriosis, with a focus on dietary patterns such as the Mediterranean and Ketogenic diets, as well as nutritional supplementation. Additionally, it highlights the central role of the clinical nutritionist in implementing individualized, evidence-based interventions within multidisciplinary care.
Recent Findings: Although the literature reports the existence of an inverse relationship between risk of endometriosis and body mass index, clinical evidence jointly reports that a condition of obesity is associated with greater disease severity.
The ameliorative effect of Lactiplantibacillus plantarum SCS2 on DSS-induced murine colitis.
Arch Microbiol
September 2025
School of Public Health, Chengdu University of Traditional Chinese Medicine, No. 1166, Liutai Avenue, Wenjiang District, Chengdu, 611137, Sichuan Province, China.
The inhibitory effects of Lactiplantibacillus plantarum on inflammatory responses are known, but its action mechanisms in oxidative stress, immunomodulation, and intestinal homeostasis remain of interest. Accordingly, we investigated the protective effects of Lactiplantibacillus plantarum SCS2 (L. plantarum SCS2) against sodium dextran sulfate (DSS)-induced colitis in mice as well as elucidated its impact on inflammation, oxidative stress, and intestinal microbiota.
View Article and Find Full Text PDF16S rRNA metagenome analysis of gut bacteriome of Rohu () from Halda River and Kaptai Lake, Bangladesh.
Microbiol Resour Announc
September 2025
Department of Genomics and Bioinformatics, Faculty of Biotechnology and Genetic Engineering, Chattogram Veterinary and Animal Sciences University (CVASU), Chattogram, Bangladesh.
This research evaluated the gut microbiota of Rohu fish from the Halda River and Kaptai Lake in Bangladesh by 16S rRNA sequencing. Distinct microbial profiles were identified, with Halda samples concentrated in pathogens and Kaptai samples abundant in probiotics.
View Article and Find Full Text PDF