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Importance: As healthcare costs continue to rise, high-income countries-including Japan-face the urgent task of reducing healthcare spending incurred by low-value care. However, evidence is limited as to which low-value care services contribute most to unnecessary healthcare spending outside of the United States.
Objective: To identify which low-value care services contribute the most to unnecessary healthcare spending in Japan.
Design Setting And Participants: The cross-sectional study of all beneficiaries using a population-based claims database from April 1, 2022, to March 31, 2023, encompassing all age groups, reflecting approximately 2% of the total Japanese population.
Main Outcomes And Measures: We identified 52 low-value care services based on clinical evidence, and examined their contributions to healthcare spending using two versions of claims-based measures with different sensitivities and specificities (broader and narrower definitions). Each service was categorized into four groups based on its average per-service price: very low (<1,000 Japanese yen [JPY] = 8 US dollars [USD] in 2022), low (1,000-9,999 JPY), medium (10,000-99,999 JPY), or high (≥100,000 JPY).
Results: Among 1,923,484 beneficiaries (mean [SD] age 58.6 [23.5] years; 52.7% female), we identified 3.1 million (narrower definition) to 3.7 million (broader definition) episodes of low-value care services (1.6-1.9 per capita), with 36-40% of patients receiving at least one low-value care service. These services accounted for 0.7-1.0% of total healthcare spending, amounting to 207-331 billion JPY (1.7-2.6 billion USD) when extrapolated nationwide with adjustments for age, sex, and region. When applying narrower definitions, over 99% of low-value care episodes involved very-low-cost or low-cost services, which accounted for 67% of unnecessary healthcare spending-far exceeding the 33% attributed to medium-cost or high-cost services.
Conclusion And Relevance: Over one in three Japanese individuals received low-value care during 2022-2023, contributing to 0.7-1.0% of total healthcare spending. Among these services, low-cost services contributed to virtually all low-value care utilization and over two-thirds of unnecessary healthcare spending. Compared to focusing solely on high-cost services, targeting the reduction of frequently performed, lower-cost services may be a more effective strategy for reducing wasteful spending.
Question: Which low-value care services-low-cost or high-cost-contribute most to unnecessary healthcare spending in Japan?
Findings: In a cross-sectional study of nearly two million beneficiaries examining 52 low-value care services, over one-third received at least one such service during a one-year period, accounting for 0.7-1.0% of total healthcare spending. More than 99% of episodes were very-low- or low-cost services, accounting for over two-thirds of low-value care spending, exceeding spending from medium- and high-cost services.
Meaning: Focusing on frequently performed, lower-cost services may better reduce wasteful healthcare spending than targeting only high-cost services.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407603 | PMC |
http://dx.doi.org/10.1101/2025.08.21.25334207 | DOI Listing |
Osteoarthritis Cartilage
September 2025
Clinical Epidemiology Unit, Orthopaedics, Department of Clinical Sciences Lund, Lund University, Lund, Sweden. Electronic address:
Aim: To summarise key epidemiological and therapeutic research on osteoarthritis (OA) published between April 2024 and March 2025.
Methods: A narrative review was conducted using the MEDLINE database, focusing on English-language studies involving human participants published between April 1, 2024 and March 31, 2025. Eligible studies included observational longitudinal studies, systematic reviews, meta-analyses, and phase II-IV randomised controlled trials (RCTs) examining OA treatment and epidemiology.
Int J Rheum Dis
September 2025
Department of Communication Science and Disorders, School of Health and Rehabilitation Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Objectives: Inclusion body myositis (IBM) can result in deadly respiratory consequences. Yet, the mechanism driving this issue remains equivocal. We mapped the literature to identify physiological respiratory characteristics in IBM and the types of respiratory assessments used.
View Article and Find Full Text PDFBMC Health Serv Res
September 2025
Department of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, P. O. Box 79, Bahir Dar, Ethiopia.
Background: Adverse events resulting from medical care continue to be a significant cause of morbidity and mortality globally. Many individuals experience harm due to medical errors, particularly in developing nations. The primary objective of this study was to evaluate the patient safety culture among pharmacy professionals employed in public hospitals within Bahir Dar City, Ethiopia.
View Article and Find Full Text PDFPLoS One
September 2025
Maternal, Child and Nutrition Department, Bolosso Bombe District Health Office, Bombe, Ethiopia.
Background: Human papillomavirus (HPV) vaccination is a well-established global strategy for the prevention of cervical cancer. However, the uptake of the vaccine varies across regions and countries due to several factors. Although girls are at risk for cervical cancer, there are limited studies measuring vaccination uptake among female adolescents in the study area.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Dow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor.
Importance: Among men with favorable-risk (ie, low-risk or favorable intermediate-risk) prostate cancer, confirmatory testing substantially improves the detection of aggressive cancers that may merit treatment instead of conservative management. Despite guideline recommendations, confirmatory testing is inconsistently used, and more than half of men do not receive it. Value-based interventions and payment incentives may improve care quality by motivating adherence to guideline-concordant care.
View Article and Find Full Text PDF