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http://dx.doi.org/10.1002/uog.70034 | DOI Listing |
Front Endocrinol (Lausanne)
September 2025
Gynecology/Obstetrics Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Introduction: Several studies indicate that a specific genotype profile could influence ovarian sensitivity to exogenous gonadotropin. However, most of the previous studies were observational and retrospective and thereby more prone to bias. The aim of this study was to evaluate the impact of gonadotropin single nucleotide polymorphisms (SNPs) on the outcomes of fertilization (IVF) in infertile patients undergoing their first ovarian stimulation (OS) cycle.
View Article and Find Full Text PDFUltrasound Obstet Gynecol
September 2025
Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK.
Pain
September 2025
Department of Anesthesiology, Critical Care & Pain Management, Pain Prevention Research Center at Hospital for Special Surgery, New York, NY, United States.
Real-world data (RWD) can be defined as routinely collected clinical or administrative data that might be used for research purposes and to generate real-world evidence (RWE). Computerized search and data mining methods, large electronic databases, and the development of novel computational and statistical methods allow for improved access to and analysis of RWD. Although RWD afford the opportunity to generate RWE with potentially improved efficiency and generalizability over prospective clinical studies, it is important to understand and apply best practices when analysing RWD, particularly when the goal is to generate RWE of diagnostic, prognostic, or treatment effectiveness.
View Article and Find Full Text PDFBioengineering (Basel)
August 2025
Center for Clinical Research, University Clinic of Dentistry, Medical University of Vienna, 1090 Vienna, Austria.
Temporomandibular joint disorders (TMDs), particularly disc displacement with reduction (DDwR), are prevalent musculoskeletal conditions characterized by symptoms such as joint clicking, pain, and sometimes limited jaw movements. Accurate diagnosis requires a multidisciplinary approach, including clinical examination, imaging (MRI), and functional analysis. Among conservative treatment modalities, anterior repositioning splints (ARSs) are widely used to recapture the displaced discs and reposition the mandibular condyles.
View Article and Find Full Text PDFUltrason Imaging
August 2025
School of Computing, University of Buckingham, Buckingham, UK.
Breast ultrasound images play a pivotal role in assessing the nature of suspicious breast lesions, particularly in patients with dense tissue. Computerized analysis of breast ultrasound images has the potential to assist the physician in the clinical decision-making and improve subjective interpretation. We assess the performance of conventional features, deep learning features and ensemble schemes for discriminating benign versus malignant breast lesions on ultrasound images.
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