98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/S1470-2045(25)00437-1 | DOI Listing |
Lancet Oncol
September 2025
Xijing Hospital, Shaanxi, China.
Poult Sci
August 2025
Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan 250100, China; China-UK Joint Laboratory of Phage Engineering, Sino-Danish Joint Laboratory of Microbial Informatics, Jinan 250100, Ch
Phage therapy has emerged as a highly effective antibiotic alternative for treating Salmonella infections; however, research into how phage dosage, administration timing, and frequency influence therapeutic efficacy-along with phage pharmacokinetics-remains limited. In this study, we established a Salmonella Pullorum infection model in specific-pathogen-free (SPF) chickens to investigate these parameters, alongside the therapeutic efficacy and pharmacokinetic distribution of the phage. The study consisted of two sequential experiments: trial 1 systematically evaluated the effects of phage dosage, administration timing, and frequency on treatment outcomes, leading to the identification of an optimal dosing regimen.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2025
Institute of Refrigeration and Cryogenics, Key Laboratory of Power Machinery and Engineering of MOE, Shanghai Jiao Tong University, Shanghai 200240, China; Shanghai Non-Carbon Energy Conversion and Utilization Institute, Shanghai 200240, China. Electronic address:
Alkaline zinc-based flow batteries suffer from poor zinc reversibility due to dendrite growth and parasitic reactions, which significantly shorten their cycling lifespan. A key challenge lies in the rational design of ligands to eliminate concentration polarization caused by mismatched diffusion and interfacial reaction rates, thereby inducing and regulating uniform zinc deposition. In this study, we propose a thermodynamic descriptor-guided ligand screening strategy, using the metal-ligand stability constant (log K) as a quantitative criterion to simultaneously optimize deposition morphology and interfacial ion kinetics.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
July 2025
Key Laboratory for Power Machinery and Engineering of Ministry of Education, Research Center for Renewable Synthetic Fuel, School of Mechanical Engineering, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China.
The reverse water-gas shift (RWGS) reaction presents an industrial promise for carbon dioxide valorization. In this work, a dual-site Ru-RuO cocatalyst anchored on Si-supported GaN nanowires (NWs) is developed for solar-powered CO-to-CO conversion. The assembled Si-supported GaN NWs/Ru-RuO delivers a considerable CO rate of 57.
View Article and Find Full Text PDFJ Evid Based Med
June 2025
Department of Ophthalmology, Tianjin Medical University General Hospital, Ministry of Education International Joint Laboratory of Ocular Diseases, Tianjin Key Laboratory of Ocular Trauma, Tianjin Institute of Eye Health and Eye Diseases, China-UK "Belt and Road" Ophthalmology Joint Laboratory, Tianj
Aim: To establish evidence-based guidelines for the application of the foldable capsular vitreous body (FCVB) in managing severe ocular trauma and silicone oil-dependent eyes.
Methods: We conducted a comprehensive search across multiple databases, screening, extracting, and evaluating research evidence. Experts in ocular trauma and vitreoretinal surgery provided practical insights and formulated key questions.