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Article Abstract

Introduction: Nonsurgical rhinofiller is increasingly used for aesthetic nasal reshaping, but little is known about its functional impact on nasal airflow. This study evaluates nasal airflow changes after rhinofiller using patient-reported outcome measures and objective rhinomanometry.

Methods: One hundred and twenty-one patients with mild nasal deviation, positive Cottle test, and no prior nasal surgery underwent rhinofiller with VYC-25. Patients completed FACE-Q and NOSE scale questionnaires preoperatively and at 1, 3, and 6 months post-treatment. Objective active anterior rhinomanometry was performed preoperatively and at 6 months.

Results: NOSE scale showed significant improvement from baseline to 6 months (mean reduction of 33.7 ± 9.4 points; p<0.05). FACE-Q nasal satisfaction module showed improvement by 21% (± 5%). Rhinomanometry demonstrated a 24% (± 4%) reduction in inspiratory pressure gradient at 100 Pa (p <0.05).

Conclusions: Rhinofiller may provide both aesthetic enhancement and functional improvement in nasal airflow in selected patients. Patients should be informed that this is not a substitute for surgical septorhinoplasty.

Level Of Evidence Iii: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

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http://dx.doi.org/10.1007/s00266-025-05193-0DOI Listing

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