98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1002/mus.70019 | DOI Listing |
JACC Heart Fail
September 2025
Cardiovascular Pathology, Department of Cardiac, Thoracic Vascular Sciences and Public Health, University of Padova, Padova, Italy. Electronic address:
Breast Cancer Res
September 2025
Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden.
Background: Polygenic risk scores (PRS) are not yet standard in clinical risk assessments for familial breast cancer in Sweden. This study evaluated the distribution and impact of an established PRS (PRS) in women undergoing clinical sequencing for hereditary breast cancer.
Findings: We integrated PRS into a hereditary breast cancer gene panel used in clinical practice and calculated scores for 262 women.
BMJ Open Diabetes Res Care
September 2025
Department of Social Medicine and Health Management, Huazhong University of Science and Technology School of Public Health, Wuhan, Hubei, China
Introduction: To examine the association of the number of controlled risk factors with the excess risk of severe metabolic dysfunction-associated steatotic liver disease (MASLD) and major adverse liver outcomes (MALO) among patients with type 2 diabetes.
Research Design And Methods: In this cohort study, a total of 307,688 participants from the UK Biobank were included. Participants with baseline type 2 diabetes were categorized according to the number of risk factors within the guideline-recommended ranges (diet, smoking, drinking, exercise, sedentary behavior, body mass index, glycated hemoglobin, blood pressure, and low-density lipoprotein cholesterol).
ACS Omega
September 2025
Department of Basic Medical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana 47907, United States.
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most prevalent neurodegenerative disorders characterized by continuous loss of functional neurons. The numbers of AD and PD patients will likely double by 2060 and 2040, reaching 13.9 and 1.
View Article and Find Full Text PDFJ Inflamm Res
September 2025
Department of Rheumatology, School of Medicine, Collegium Medicum, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Fatigue is a prevalent and debilitating symptom in rheumatic diseases such as rheumatoid arthritis and psoriatic arthritis. Despite advances in reducing inflammation through treatments, fatigue often persists, underscoring its multifactorial etiology. A possible link between the persistent inflammation observed in rheumatic diseases and the onset of fatigue has been suggested.
View Article and Find Full Text PDF