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This paper presents a case of a 43-year-old man with Down syndrome misdiagnosed with psoriasis, later diagnosed with CS. Clinical manifestations included pruritus, hyperkeratotic plaques, and yellow crusts on the scalp, hands, and feet. Laboratory findings revealed eosinophilia and confirmed scabies through mite identification. Treatment with oral ivermectin and permethrin cream led to complete lesion clearance in two weeks. Crusted scabies is highly contagious and often misdiagnosed, emphasizing the importance of early recognition and appropriate treatment to prevent complications and transmission.
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http://dx.doi.org/10.1007/s12639-025-01803-5 | DOI Listing |
J Parasit Dis
September 2025
Department of Dermatology, Medical School of Oujda, Mohammed VI University Hospital of Oujda, Mohammed First University of Oujda, Oujda, Morocco.
This paper presents a case of a 43-year-old man with Down syndrome misdiagnosed with psoriasis, later diagnosed with CS. Clinical manifestations included pruritus, hyperkeratotic plaques, and yellow crusts on the scalp, hands, and feet. Laboratory findings revealed eosinophilia and confirmed scabies through mite identification.
View Article and Find Full Text PDFAustralas J Dermatol
August 2025
Department of Dermatology, Townsville University Hospital, Townsville, Queensland, Australia.
We present a case series of four patients who had scabies diagnosed while on Dupilumab treatment for atopic dermatitis. The Type 2 immune response is the primary immune response for both ordinary and crusted scabies, and Dupilumab inhibits this response. This inhibition could be the reason behind treatment resistance and crusted presentations in this case series.
View Article and Find Full Text PDFSkin Appendage Disord
March 2025
Istituto Dermatologico San Gallicano, IRCCS-IFO, Rome, Italy.
Introduction: Nail involvement in patients with crusted scabies is well known. It is characterized clinically by subungual hyperkeratosis and onycholysis. "Classical" scabies involving the nails was rarely reported.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Clinical Laboratory, Hangzhou Xixi Hospital, Hangzhou Sixth People's Hospital, Hangzhou Xixi Hospital Affiliated to Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, China.
Rationale: Norwegian scabies (crusted scabies) is an extreme manifestation of Sarcoptes scabiei infestation, primarily affecting immunocompromised populations such as HIV-positive individuals. This condition is characterized by a severe mite burden and high transmissibility, often accompanied by pathognomonic hyperkeratotic plaques.
Patient Concerns: A 46-year-old male patient diagnosed with HIV presented with persistent fever and progressive cutaneous desquamation, along with lymphadenopathy and worsening rash, initially misdiagnosed as atopic dermatitis.