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Totally implantable venous access ports (TIVAPs) are commonly used for patients undergoing chemotherapy and long-term repeated infusions. The incidence of thrombosis is low and rarely leads to serious complications. We report a case of right atrial thrombosis and paradoxical embolism in a 58-year-old male with atrial fibrillation (AF) and patent foramen ovale (PFO) 28 months after TIVAP implantation. The patient presented with dizziness and left limb weakness, subsequent diagnostic imaging revealed right temporal lobe infarction and a mass in the right atrium, who eventually recovered and was discharged after cardiac surgery and anticoagulation. This case highlights the rare but severe complication of right atrial thrombosis associated with TIVAP, particularly in patients with AF and PFO. Proper placement and timely removal of totally implantable venous access ports are crucial to minimize complications. Further research is needed to determine the necessity of anti-coagulation and PFO screening in patients with AF receiving central venous catheters.
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http://dx.doi.org/10.3389/fcvm.2025.1581930 | DOI Listing |
Eur Heart J Case Rep
September 2025
Department of Cardiology, Toyohashi Heart Center, 21-1 Gobutori, Oyamacho, Toyohashi 441-8530, Japan.
Background: Mitral regurgitation (MR) may rarely worsen after transcatheter aortic valve implantation (TAVI) due to mechanical interference from the transcatheter heart valve (THV). Standard surgical approaches in these cases are often challenging due to anatomical constraints. Thus, there is a need for the development of effective alternatives to address this issue.
View Article and Find Full Text PDFFront Cardiovasc Med
August 2025
Department of Interventional Radiology, First People's Hospital of Changzhou, Changzhou, China.
Totally implantable venous access ports (TIVAPs) are commonly used for patients undergoing chemotherapy and long-term repeated infusions. The incidence of thrombosis is low and rarely leads to serious complications. We report a case of right atrial thrombosis and paradoxical embolism in a 58-year-old male with atrial fibrillation (AF) and patent foramen ovale (PFO) 28 months after TIVAP implantation.
View Article and Find Full Text PDFEinstein (Sao Paulo)
September 2025
Department of Pediatrics, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Objective: To analyze the impact of a serious immersive virtual reality game on the physiological and behavioral aspects of pain during peripheral venous access or central catheter puncture in children and adolescents with cancer.
Methods: This was a longitudinal intervention study that included 50 children and adolescents undergoing cancer therapy and peripheral venipuncture or venous catheter puncture (totally implanted or central venous catheter) at two independent time points (control and experimental intervention). The intervention consisted of playing a serious immersive virtual reality game with three-dimensional goggles and a Bluetooth controller.
BMC Surg
August 2025
Thyroid and Breast Surgery, Longyan First Affiliated Hospital of Fujian Medical University, No.105, Jiuyi North Road, Xinluo District, Longyan, Fujian, 364000, China.
Background: Accurately predicting cavoatrial junction (CAJ) position is important for totally implantable venous-access port (TIVAP) application, which could reduce complications.
Methods: Clinical information of 117 breast cancer (BRCA) patients who underwent TIVAP implantation was collected. The length of the implanted catheter was determined by a chest radiograph method in the test group, as follows: total catheter insertion length was L, and the distance from the pre-puncture point to the right sternoclavicular joint was measured as L1; the distance from the right sternoclavicular joint to 1.
Shanghai Kou Qiang Yi Xue
June 2025
Department of Special Needs, Pinghai Hospital of Stomatology. Hangzhou 310003, Zhejiang Province, China. E-mail:
Purpose: To explore the influence of alveolar process expansion, guided bone regeneration (GBR) and bone grafting for simultaneous dental implantation therapy on bone resorption volume, retention and masticatory function in patients with severe deficiency of alveolar bone horizontal width.
Methods: Eighty patients with severely insufficient alveolar bone width who received dental implantation therapy in Hangzhou Stomatology Hospital were selected from January 2021 to January 2023. Totally 40 patients (55 teeth) who received alveolar process expansion combined with GBR bone grafting were included in the experimental group, while 40 patients (51 teeth) with traditional alveolar bone splitting were enrolled as the control group.