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Introduction: Structured, well-being interventions are under-researched in non-Western workplaces. This study evaluates training program-a participatory, multi-component training intervention-on employee well-being, engagement and stress in South Africa.
Methods: Employing an exploratory, quasi-experimental, explanatory sequential mixed-methods design, we collected quantitative data from 50 South African respondents across three delivery formats (four half-days online, two full-days in classroom, and four half-days in classroom) at pre-training and 3 months post-training using five validated scales (PSS-4, UWES-3, SWLS, FS, WEMWBS-14). No concurrent control group was retained due to attrition and contamination; thus, causal inferences are cautious. Qualitative data were gathered via semi-structured interviews with a purposive subsample of 15 participants to elucidate mechanisms of change.
Results: Two full-day workshops led to significant improvements in overall well-being and work engagement, whereas the online format produced a significant boost in well-being only. The half-day format showed no statistically significant changes. Qualitative findings highlighted immersive peer interaction, structured reflection and managerial support as core drivers of impact.
Discussion: Immersive, HR-facilitated training shows promise for enhancing well-being and engagement in South African workplaces. Future research should employ randomized controlled designs, larger samples and objective measures (e.g., absenteeism, physiological indicators) to substantiate and extend these preliminary findings.
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http://dx.doi.org/10.3389/fpubh.2025.1627464 | DOI Listing |
JMIR Res Protoc
September 2025
Department of Development & Environmental Studies, Palacký University Olomouc, Olomouc, Czech Republic.
Background: Children in low- and middle-income countries face obstacles to optimal language and cognitive development due to a variety of factors related to adverse socioeconomic conditions. One of these factors is compromised caregiver-child interactions and associated pressures on parenting. Early development interventions, such as dialogic book-sharing (DBS), address this variable, with evidence from both high-income countries and urban areas of low- and middle-income countries showing that such interventions enhance caregiver-child interaction and the associated benefits for child cognitive and socioemotional development.
View Article and Find Full Text PDFJ Med Internet Res
September 2025
Institute of Hospital Management, Peking University Third Hospital, Beijing, China.
Background: Telemedicine is developing rapidly, presenting new opportunities and challenges for physicians and patients. Limited research has examined physicians' behavior during the process of adopting telemedicine and related factors.
Objective: This study aimed to identify perceived barriers and enablers of physicians' adoption of telemedicine and to develop intervention strategies.
Australas J Ageing
September 2025
School of Health, University of the Sunshine Coast, Sippy Downs, Queensland, Australia.
Objectives: Long-term worker shortages in Australian residential aged care are well-documented. These shortages adversely impact residents' well-being and the morale of staff caring for them. This study aimed to explore staff and management experiences through workplace theories related to worker satisfaction: job demands-resources theory, self-determination theory, moral disengagement and work as calling theory, at NewDirection Care, which provides innovative aged care in Queensland.
View Article and Find Full Text PDFCurr Opin Infect Dis
August 2025
Transplant and Immunocompromised Host Infectious Diseases, Department of Medicine, Infectious Diseases Division, Massachusetts General Hospital.
Purpose Of Review: Plasma metagenomic next-generation sequencing (mNGS) enables detection of microbial cell-free deoxyribonucleic acid (mcfDNA) in blood without the need for culture or organism-specific primers. Here, we review clinical performance, methodological variability, and real-world application of plasma mNGS for infectious disease diagnosis in immunocompromised hosts (ICHs).
Recent Findings: Plasma mNGS has rapidly gained attention as a novel diagnostic tool for infections in ICHs, offering broad-range pathogen detection from a noninvasive blood sample.
Adv Ther
September 2025
Bristol Myers Squibb, Princeton, NJ, 08540, USA.
Background And Objectives: Deucravacitinib, a first-in-class, oral, selective, allosteric tyrosine kinase 2 inhibitor, demonstrated efficacy across the primary endpoint and all key secondary endpoints in the phase 2 PAISLEY SLE trial in patients with active systemic lupus erythematosus (SLE). Here, we describe 2 phase 3 trials [POETYK SLE-1 (NCT05617677), POETYK SLE-2 (NCT05620407)] which will assess the efficacy and safety of deucravacitinib in patients with active SLE. These phase 3 trials have been designed to replicate the successful elements of the phase 2 trial, including its glucocorticoid-tapering strategy and disease activity adjudication.
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