98%
921
2 minutes
20
Angle-closure glaucoma is a major cause of visual impairment worldwide, with Plateau iris syndrome presenting management challenges. We present a case report of a 58-year-old woman with advanced, uncontrolled angle--closure glaucoma and Plateau iris. Her history included laser peripheral iridotomy and three glaucoma medications in both eyes. Different treatments were implemented. For the eye with lower intraocular pressure, fewer peripheral anterior synechiae, and milder disease: phacoemulsification with intraocular lens implantation. For the eye with more advanced disease, a two-step approach was used: slow-coagulation transscleral cyclophotocoagulation using the double-arc protocol, followed by phacoemulsification with intraocular lens implantation 2 months later. Both eyes achieved improved visual acuity and intraocular pressure control with fewer medications, without significant complications. This case highlights transscleral cyclophotocoagulation followed by phacoemulsification as an alternative to combined surgeries in uncontrolled angle-closure glaucoma with Plateau iris, offering a simpler technique, more predictable refractive and pressure-control outcomes, and more straightforward postoperative management.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.5935/0004-2749.2025-0020 | DOI Listing |
Arq Bras Oftalmol
September 2025
Department of Ophthalmology and Visual Science, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Angle-closure glaucoma is a major cause of visual impairment worldwide, with Plateau iris syndrome presenting management challenges. We present a case report of a 58-year-old woman with advanced, uncontrolled angle--closure glaucoma and Plateau iris. Her history included laser peripheral iridotomy and three glaucoma medications in both eyes.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
July 2025
Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States.
Purpose: Angle closure glaucoma (ACG) is a common cause of adult-onset vision loss that often presents with iris abnormalities and short axial lengths. Although it is heritable, little is known about the genetic risk factors underlying this condition. We thus conducted a disease gene discovery study in a family exhibiting an autosomal dominant triad of ACG, plateau iris, and short axial lengths.
View Article and Find Full Text PDFJ Glaucoma
August 2025
Department of Ophthalmology, Faculty of Medicine, Karadeniz Technical University.
In this observational case-series study, we aimed to report malignant glaucoma (MGL) occurence in 4 consecutive cases (4 women; mean age, 60±11.0 y) after gonioscopy-assisted transluminal trabeculotomy (GATT) between January 2021 and September 2024 and to evaluate clinical characteristics and treatment outcomes. All patients had primary angle closure glaucoma (PACG) before GATT.
View Article and Find Full Text PDFGenes Genomics
June 2025
Department of Biosciences, Mokpo National University, Jeonnam, 58554, Republic of Korea.
Unlabelled: BACKGROUND : Iris bungei Maxim., a plant native to the desert grasslands of the Inner Mongolian Plateau and traditionally used in Mongolian medicine, has been shown to influence adipocyte differentiation in white adipose tissue. However, its effects on brown adipocyte differentiation have not been previously explored.
View Article and Find Full Text PDFInt J Mol Sci
March 2025
Clinical and Academic Department of Ophthalmology, Great Ormond Street Hospital for Children NHS Foundation Trust, London WC1N 1LE, UK.
Biallelic pathogenic variants in the gene are associated with severe retinal dystrophies, including early onset severe retinal dystrophy/Leber congenital amaurosis (EOSRD/LCA), retinitis pigmentosa (RP), cone-rod dystrophy (CORD), and macular dystrophy (MD). Despite growing research, scant genotype-phenotype correlations have been established. Here, we present two cases involving individuals that presented with cystoid macular oedema and high intraocular pressure, which were later diagnosed as -MD, demonstrating a mild and stable phenotype.
View Article and Find Full Text PDF