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http://dx.doi.org/10.1007/s00431-025-06456-3 | DOI Listing |
Clin Ophthalmol
August 2025
Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Background: Diabetic macular edema (DME) is a leading cause of vision loss in working-age adults. Faricimab, a bispecific antibody targeting VEGF and Ang-2, has been shown to reduce treatment burden by enabling extended injection intervals. However, real-world, long-term data from Japanese populations are limited.
View Article and Find Full Text PDFEur J Pediatr
September 2025
Department of Pediatrics, Riga Stradins University, Children's Clinical University Hospital, Riga, Latvia.
EClinicalMedicine
September 2025
Department of Population Health Sciences, University of Leicester, UK.
Background: Children born extremely preterm are at increased risk of developmental problems and respiratory morbidity due to patent ductus arteriosus (PDA). The objective of this study was to evaluate whether early treatment of a PDA ≥1.5 mm with ibuprofen improved neurodevelopmental and respiratory outcomes at 24 months of age, corrected for prematurity.
View Article and Find Full Text PDFSci Rep
August 2025
Division of Spine Surgery, Department of Orthopedic Surgery, China Medical University Beigang Hospital, China Medical University, Yunlin, Taiwan.
Two-stage surgeries are increasingly used to minimize complications in adult spinal deformity (ASD) correction, yet the specific contributions of lateral lumbar interbody fusion (LLIF) and posterior column osteotomy/posterior spinal fusion (PCO/PSF) remain underexplored. This study evaluates their roles in deformity correction and establishes predictive thresholds for optimizing surgical planning. A total of 151 ASD patients (mean age 69.
View Article and Find Full Text PDFInt Orthop
August 2025
Ain Shams University, Cairo, Egypt.
Purpose: Posterior femoro-acetabular impingement in patients with increased femoral version can result in significant hip pain, chondro-labral injury, and limited range of motion. Femoral rotational osteotomy may address these issues by correcting excessive femoral anteversion.
Methods: This retro-spective case series included 25 adolescents (mean age 14.