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Objective: This study aimed to determine the oral health and the associated health disparities of pediatric patients with autism spectrum disorder (ASD).
Methods: This non-matched, case-control study recruited 22 subjects diagnosed with ASD (cases) and 27 without ASD (controls) aged 5-18 years. Two calibrated dentists performed dental exams for caries and gingivitis on all subjects. Parents/caregivers completed sociodemographics and social determinants oral health questionnaires. As appropriate, between-group comparisons were performed using chi-square, Fisher's exact test, t-test, and Mann-Whitney test. Associations between ASD and oral health indices were determined using logistic, Poisson, and linear regression models.
Results: Statistically significant differences were found for not easy finding dental services for ASD patients (=0.014) and behavioral problems during dental visits (=0.012). Children with ASD had significantly lower odds of caries (DMFT+dft>0) compared to children without ASD (OR=0.121; 95% CI: 0.023; 0.636). Age- and sex-adjusted models showed a significantly lower gingival index among those with ASD.
Conclusion: ASD patients had better oral health indices than the control subjects. The barriers to treatment for ASD patients were lack of access to dental care and living in a rural area.
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http://dx.doi.org/10.47990/njr9j726 | DOI Listing |
JAMA Psychiatry
September 2025
Denovo Biopharma LLC, San Diego, California.
Importance: This study represents a first successful use of a genetic biomarker to select potential responders in a prospective study in psychiatry. Liafensine, a triple reuptake inhibitor, may become a new precision medicine for treatment-resistant depression (TRD), a major unmet medical need.
Objective: To determine whether ANK3-positive patients with TRD benefit from a 1-mg and/or 2-mg daily oral dose of liafensine, compared with placebo, in a clinical trial.
Cult Health Sex
September 2025
Department of Behavioral and Social Sciences, Brown University, Providence, RI, USA.
Transgender women and sex workers in Brazil underutilise HIV prevention services. Understanding preferences and decision-making regarding HIV prevention can help develop new programmes to meet their needs. We conducted semi-structured interviews with 26 transgender women and travesti sex workers in São Paulo, Brazil.
View Article and Find Full Text PDFInt J Surg
September 2025
Department of Oral and Maxillofacial Surgery, The Affiliated Tai'an City Central Hospital of Qingdao University, Taian, China.
Cancer Causes Control
September 2025
College of Public Health, Iowa Cancer Registry, Epidemiology Department, University of Iowa, Iowa City, IA, USA.
Purpose: Human papillomavirus (HPV) causes oral and anogenital cancers, the incidence of which is increasing. Late-stage diagnosis is associated with increased mortality. Neighborhood-level characteristics and distance to place of diagnosis may impact timely diagnosis.
View Article and Find Full Text PDFCancer Causes Control
September 2025
Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
Purpose: The U.S. Preventive Services Task Force recommends that men aged 55-69 years undergo shared decision-making (SDM) regarding prostate cancer (PCa) screening, and routine screening is not recommended for older men or those with limited life expectancy.
View Article and Find Full Text PDF