98%
921
2 minutes
20
Case: We present a case of an elderly female patient with a chronic lower leg wound involving bone exposure in the tibia. Despite the absence of overt infection, low-grade osteomyelitis was suspected. Given the patient's age and overall fitness, we opted for a staged reconstructive approach using negative pressure wound therapy (NPWT), followed by sequential pedicled muscle flaps and skin grafting. This method was favored over free flap reconstruction due to patient-specific factors and the aim of minimizing donor site morbidity. The outcome was functionally and aesthetically satisfactory, with no signs of flap failure or recurrent infection.
Conclusion: This case highlights the utility of staged reconstruction using local muscle flaps combined with NPWT in elderly patients, offering a limb-salvaging alternative to free tissue transfer in selected cases.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396282 | PMC |
http://dx.doi.org/10.1016/j.tcr.2025.101238 | DOI Listing |
Surg Case Rep
September 2025
Department of Surgery and Science, Faculty of Medicine, Academic Assembly, University of Toyama, Toyama, Toyama, Japan.
Introduction: There are no reports of patients undergoing McKeown esophagectomy for esophageal cancer after undergoing pancreaticoduodenectomy for pancreatic cancer. We report the case of a patient who underwent subtotal esophagectomy and colon reconstruction after pancreaticoduodenectomy using the mesenteric approach.
Case Presentation: A 71-year-old male was diagnosed with advanced esophageal cancer.
Cureus
August 2025
Medicine, Academy of Silesia, Katowice, POL.
We present the case of a 45-year-old Caucasian woman diagnosed with synchronous bicentric breast cancer of differing molecular phenotypes in the same breast. The first tumor, an invasive ductal carcinoma (G1), was estrogen and progesterone receptor-positive and HER2-negative, with a low proliferative index (Ki67 10%). A second lesion, located in a different quadrant and appearing within weeks after biopsy, exhibited a triple-negative phenotype and a higher proliferative index (Ki67 30%).
View Article and Find Full Text PDFJ Anat
September 2025
Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Katowice, Poland.
Vertebrates exhibit remarkable morphological diversity, with the head representing an exceptionally complex anatomical structure shaped by adaptations to feeding ecology, brain size, and sensory organ specialization. Proper fusion of facial prominences and the coordinated growth of the skull and brain are essential for normal craniofacial development in vertebrates, including humans. Disruptions in these processes, whether due to gene mutations or external factors, can result in craniofacial malformations.
View Article and Find Full Text PDFAesthetic Plast Surg
September 2025
Department of Otolaryngology, Masih Daneshvari Hospital, Neyavran, Darabad, Tehran, Iran.
Nasal alar reconstruction is complex due to the region's anatomy and aesthetic importance. This report describes repairing a small, full-thickness alar rim defect in a 36-year-old man using a rotational columellar skin flap with septal cartilage grafting. This single-stage technique achieved good color match, symmetry, and minimal donor-site morbidity.
View Article and Find Full Text PDFBMJ Open
September 2025
Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Introduction: The management of bleeding and coagulation after total knee arthroplasty (TKA) has long been recognised as a significant challenge for orthopaedic surgeons. Despite the notable success of empirical anticoagulation in preventing venous thromboembolism (VTE) following TKA, the increased risk of postoperative bleeding has also raised extensive concern. Ecchymosis, as one of the most common manifestations indicating postoperative bleeding, holds the potential to indicate the balance of bleeding and hypercoagulation.
View Article and Find Full Text PDF