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http://dx.doi.org/10.1007/s43657-025-00220-1 | DOI Listing |
Phenomics
June 2025
Department of Dermatology, Xiangya Hospital, Central South University, Xiangya Rd 87, Kaifu District, Changsha, 410008 China.
Pain Manag
September 2025
Drug and Alcohol Clinical Research and Improvement Network, NSW Health, St Leonards, NSW, Australia.
Long acting (or extended release) injectable buprenorphine formulations for the treatment of opioid dependence have been introduced in a number of countries in recent years. One such product, Buvidal, available as Weekly or Monthly subcutaneous injections, has been increasingly used in many European countries and Australia for several years, and has recently been registered under the brand name Brixadi in the United States. This review provides an overview of opioid dependence, examines the rationale for the development of Buvidal, its pharmacological properties, evidence of efficacy and safety, and key principles of clinical care in the treatment of opioid dependence.
View Article and Find Full Text PDFJ Chem Theory Comput
September 2025
Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Model Hamiltonians represent a convenient way of reducing complex problems of many-electron quantum mechanics to much simpler problems: they can fully reproduce the core behaviors of a system of interest by encoding only the dominant physical interactions and using only a small number of associated parameters. Model Hamiltonians have been successfully applied to describe many chemical and physical phenomena. Density matrix downfolding (DMD) [ 2015, 143 (10), 102814] allows the derivation of model Hamiltonians of any form in a systematically improvable fashion by matching the energy spectrum of Hamiltonians with those of the model Hamiltonians.
View Article and Find Full Text PDFPLoS One
August 2025
Sunshine Coast Public Health Unit, Maroochydore, Queensland, Australia.
Obtaining a stool specimen for diagnostic testing of enteric conditions (e.g., gastroenteritis) can be a challenging and unpleasant experience.
View Article and Find Full Text PDFInt J Pharm Pract
August 2025
Evelina Pharmacy Department, Guy's and St Thomas' NHS Foundation Trust, Evelina London Children's Hospital, Westminster Bridge Road, London SE1 7EH, United Kingdom.
Objectives: Previous studies have highlighted inconsistencies in dosage instructions on dispensed medicine labels, increasing the risk of medication errors. This challenge is especially relevant in paediatrics, where instructions often convey more complex numerical values and use of measuring devices. This study aimed to investigate parents' and carers' preferences and understanding of dosage instructions on dispensed paediatric medicine labels.
View Article and Find Full Text PDF