98%
921
2 minutes
20
PurposeThe COVID-19 pandemic significantly impacted mental health, particularly in individuals with pre-existing conditions and in younger people. However, long-term mental health trajectories beyond the acute phase remain unclear. This study examined distress levels and quality of life (QoL) in individuals with mental and/or physical health conditions, and across different age groups between 2020 and 2024.MethodsUsing data from the COLLATE project - a series of online mental health surveys of the Australian public - we conducted general linear models to assess demographic parameters and risk factors associated with distress and QoL in 2,134 participants.Major FindingsMental and physical health conditions were associated with higher distress and lower QoL throughout 2020 to 2024. Having both conditions had a compounding effect on QoL but not distress, which was primarily influenced by mental health conditions. Younger people reported higher distress across this period. Overall, QoL was lower in 2024 than 2020.ConclusionPoorer mental health in those with mental and physical health conditions, and younger age groups, persisted from 2020 to 2024. This is concerning considering extensive literature demonstrating disproportionately greater impacts of COVID-19 on the mental health of priority populations and highlights groups that may require ongoing psychosocial support.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1177/10398562251372821 | DOI Listing |
Eat Disord
September 2025
Center for Eating and feeding Disorders Research (CEDaR), Psychiatric Center Ballerup, Mental Health Services in the Capital Region of Denmark.
Proc Natl Acad Sci U S A
September 2025
Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240.
Major depressive disorder affects millions worldwide, yet current treatments require prolonged administration. In contrast, ketamine produces rapid antidepressant effects by blocking spontaneous N-Methyl-D-Aspartate (NMDA) receptor signaling, which lifts the suppression of protein synthesis and triggers homeostatic synaptic plasticity. Here, we identify a parallel signaling pathway involving metabotropic glutamate receptor 5 (mGluR5) that promotes rapid antidepressant-like effects.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Lübeck, Lübeck, Germany.
Importance: Patients with inflammatory rheumatic diseases (IRDs) frequently experience psychological distress; however, access to psychological support remains limited.
Objective: To investigate the effectiveness of a digital psychological intervention for individuals with IRDs.
Design, Setting, And Participants: Participants aged 18 years or older were recruited across Germany between February 22 and June 4, 2024, if they had been diagnosed with rheumatoid arthritis, psoriatic arthritis, or systemic lupus erythematosus and reported psychological distress and reduced quality of life.
J Gambl Stud
September 2025
Department of Psychology and Azrieli Israel Center for Addiction and Mental Health, The Hebrew University of Jerusalem, Jerusalem, Israel.
Research suggests that Problem Gambling (PG) may result from maladaptive emotional regulation strategies aimed at escaping emotions and stress caused by negative life events and trauma. The current study, aimed to examine the effect of exposure to the mass trauma of October 7, 2023 terror attack and the consequent Swords of Iron war in Israel, and difficulties in emotional regulation on PG. We utilized longitudinal data of self-reports in the Problem Gambling Severity Index collected before the terror attack (April 2022) and during the Swords of Iron war (December 2023, March 2024, June 2024; N = 899) from a large sample of adult Jewish Israelis.
View Article and Find Full Text PDF