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BackgroundIdentifying determinants of pain-related disability in chronic spinal pain (CSP) remains a major research focus, but the role of interoceptive sensibility is underexplored.ObjectiveTo determine whether adaptive interoceptive sensibility uniquely predicts pain-related disability and to compare its dimensions and cognitive factors across disability severity in people with CSP.MethodsThis cross-sectional study included 108 people with CSP. Pain intensity over the previous week and during activity, pain duration, and coexisting extremity pain were recorded. The Pain Disability Index, Pain Catastrophizing Scale, Pain Beliefs Questionnaire, and Multidimensional Assessment of Interoceptive Awareness (MAIA-2) were administered. A linear regression identified disability-related factors. Demographic-adjusted outcomes were compared across mild, moderate, and severe disability groups.ResultsInteroceptive sensibility explained an additional 17.70% of the variance in pain-related disability after adjusting for demographics, and among the eight dimensions measured by MAIA-2, not-distracting (B = -2.66, 95% CI = -5.13 to -0.18) and not-worrying (B = -6, 95% CI = -9.08 to -2.94) predicted pain-related disability (p < 0.05). Not-distracting remained a unique predictor when pain characteristics and catastrophizing were included in the model (B = -2.62, 95% CI = -4.41 to -0.83, p < 0.05). The mild disability group showed less catastrophizing and more not-worrying, and the severe disability group showed less not-distracting (p < 0.05, η²=0.06 to 0.19).ConclusionAdaptive interoceptive sensibility, especially not-worrying and not-distracting dimensions, were associated with spinal pain-related disability.
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http://dx.doi.org/10.1177/10538127251374354 | DOI Listing |
Clin J Pain
September 2025
Department of Clinical Psychological Science, University of Maastricht, the Netherlands.
Objectives: Although the multifactorial nature of chronic pain is well established, research has predominantly examined isolated variables or singular pathways that may contribute to this condition. We use a complex systems perspective to examine the interplay of psychological factors in the context of chronic pain.
Methods: We analyzed two cross-sectional datasets (N=935 and 1366) collected at a pain clinic and rehabilitation center in Belgium from individuals primarily with musculoskeletal pain.
J Pain
September 2025
Department of Orthopaedic Surgery, Duke University School of Medicine, Durham, NC, USA; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA.
In this longitudinal cohort study, we used nationally representative data from the U.S. National Health Interview Survey (n = 7,826 for chronic pain; n = 9,195 for high-impact chronic pain [HICP]) to examine the association of trouble sleeping and tiredness with 1-year incidence of chronic pain and HICP in U.
View Article and Find Full Text PDFEur J Pain
October 2025
Postgraduate Program in Rehabilitation Sciences, Nove de Julho University, São Paulo, Brazil.
Background: Chronic nonspecific neck pain (CNSNP) is a prevalent and complex condition. Although many studies have evaluated the effectiveness of transcutaneous electrical nerve stimulation (TENS), interferential current (IFC), therapeutic exercise (TE), and manual therapy (MT) individually, this study aimed to determine whether adding IFC and/or TENS to a Multimodal Therapeutic Intervention Program (MTIP) would produce better outcomes than the MTIP alone concerning functional capacity, pain intensity, pain catastrophising, kinesiophobia and overall perceived effect in individuals with CNSNP.
Methods: Seventy-five individuals with CNSNP were randomly assigned to one of three groups: MTIP, MTIP + IFC, or MTIP + TENS.
J Pain Res
August 2025
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Purpose: The analgesic mechanisms and neurophysiological effects of spinal cord stimulation (SCS) and dorsal root ganglion stimulation (DRGS) are poorly understood. In this pilot repeated-measures study, we used quantitative sensory testing (QST) and self-reported questionnaires to investigate the effects of these therapies in chronic pain patients from pre-implantation up to one-year post-implantation. Several studies have reported stimulation-induced effects on QST, potentially clarifying how neurostimulation affects the nervous system, which is poorly understood.
View Article and Find Full Text PDFJ Back Musculoskelet Rehabil
September 2025
Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Izmir Katip Celebi University, Izmir, Turkey.
BackgroundIdentifying determinants of pain-related disability in chronic spinal pain (CSP) remains a major research focus, but the role of interoceptive sensibility is underexplored.ObjectiveTo determine whether adaptive interoceptive sensibility uniquely predicts pain-related disability and to compare its dimensions and cognitive factors across disability severity in people with CSP.MethodsThis cross-sectional study included 108 people with CSP.
View Article and Find Full Text PDF