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This study conducts a critical discourse analysis (CDA) of social media advertisements (ads) for Glucagon-like peptide-1 receptor agonist (GLP-1 RAs) weight loss drugs to examine their linguistic features, discursive practices, and social implications, aiming to explore how advertising strategies may shape public perceptions and consumer considerations. Data collection focused on Facebook and Instagram, targeting ads related to FDA-approved GLP-1 RAs weight loss drugs from February 2023 to February 2024. Ads were collected using specific keyword searches. Inclusion criteria focused on ads explicitly related to the three GLP-1 RAs weight loss drugs, while exclusion criteria removed irrelevant, non-English, duplicate, or incomprehensible ads. Thematic analysis was conducted to identify recurring themes. Fairclough's CDA model was used to analyse the 90 ads. Thematic analysis identified four key themes including "Health and Safety", "Consultation and Support", "Ease and Affordability", and "Emotional and Psychological Impact". These themes highlight the emphasis on medical credibility, accessibility through telehealth, affordability, and emotional benefits. The ads strategically use medical authority and emotional appeals, seemingly to build trust and persuade consumers. The focus on telehealth aligns with the growing demand for remote healthcare solutions, while the emphasis on affordability and ease of use addresses common barriers to accessing weight loss treatments. This research provides new insights into the discursive strategies of pharmaceutical advertising, distinguishing it as a unique contribution to the field. The study underlines the need for balanced health communication that accurately represents the benefits and risks of weight loss drugs. It recommends stricter regulatory guidelines to ensure transparency and prevent exaggerated claims. Additionally, public health campaigns should educate consumers on comprehensive weight management, integrating medication with lifestyle changes. Moreover, stakeholders can develop better health communication strategies and regulatory policies to enhance public health outcomes by understanding the narratives in these ads.
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http://dx.doi.org/10.1186/s12889-025-24197-8 | DOI Listing |
Probiotics Antimicrob Proteins
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Key Laboratory of the Ministry of Education for Wildlife and Plant Resources Conservation in Southwest China, College of Life Sciences, China West Normal University, Nanchong, Sichuan, China.
Enterotoxigenic Escherichia coli (ETEC) is a prevalent intestinal pathogen that significantly impacts both human and animal health. G83, isolated from giant panda feces, has demonstrated notable probiotic properties. In this study, C57BL/6 J mice were randomly divided into Control, ETEC, and G83 groups.
View Article and Find Full Text PDFDermatol Ther (Heidelb)
September 2025
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Via Massarenti 9, 40138, Bologna, Bologna, Italy.
Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) have gained prominence for their efficacy in treating type 2 diabetes and obesity. Recent evidence suggests that their pleiotropic effects-beyond glycemic control and weight loss-include anti-inflammatory, immunomodulatory, and antioxidative effects, which may beneficially support various dermatologic conditions such as psoriasis, hidradenitis suppurativa, acanthosis nigricans, and Hailey-Hailey disease. However, GLP-1 RAs are also associated with emerging cutaneous adverse drug reactions, including bullous, exanthematous and vasculitic manifestations, and other rare side effects.
View Article and Find Full Text PDFG Ital Nefrol
August 2025
Department of Translational Medical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
The prevalence of obesity is progressively increasing on a global scale. Among its negative health consequences, renal damage is also observed. It is due to hemodynamic, metabolic, and inflammatory alterations.
View Article and Find Full Text PDFAdv Sci (Weinh)
September 2025
Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China.
Obesity-associated obstructive sleep apnea (OSA) highlights the need for effective therapies. Hypothalamic endoplasmic reticulum (ER) stress contributes to leptin resistance in obesity. Although hesperidin (HE) modulates ER stress and oxidative pathways, its low bioavailability limits clinical use, its role in OSA is unknown.
View Article and Find Full Text PDFCurr Opin Urol
September 2025
Department of Urology.
Purpose Of Review: Infertility affects approximately 15% of couples, with male factors implicated in more than 50% of cases. Concerns over declining semen quality - evidenced by a more than 50% drop in sperm concentration over four decades - have triggered investigation into modifiable lifestyle and environmental factors. This review summarizes recent evidence on exposures that negatively impact male fertility.
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