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Article Abstract
Adenine recognition through triplex-like interactions was explored using clamp-shaped artificial receptor , bearing two uracil units and an extended naphthalene scaffold. The requisite binding mode was confirmed for 9-ethyladenine in CDCl via NMR investigations. Phase-transfer experiments demonstrated that selectively binds adenosine from an aqueous mixture of four ribonucleosides.
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High Affinity Dimeric Uracil-Based Receptor for the Recognition of Adenine Derivatives through Triplex-like Interactions.
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Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parco Area delle Scienze 17 A, 43124 Parma, Italy.
Adenine recognition through triplex-like interactions was explored using clamp-shaped artificial receptor , bearing two uracil units and an extended naphthalene scaffold. The requisite binding mode was confirmed for 9-ethyladenine in CDCl via NMR investigations. Phase-transfer experiments demonstrated that selectively binds adenosine from an aqueous mixture of four ribonucleosides.
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