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Background: Cognitive and psychological inflexibility are two mental processes that influence how a person interprets and responds to esophageal symptoms. Patients with greater mental inflexibility are at risk for poorer outcomes. Brain-gut behavioral therapies (BGBT) are effective adjunctive treatments in many digestive diseases, with potential to improve mental flexibility. We piloted a brief intervention targeting cognitive and psychological inflexibility in patients with esophageal disease. Secondary aims included improving symptoms, mood, and quality of life (QoL) and reducing hypervigilance and symptom anxiety.
Methods: Eighty adults newly diagnosed with achalasia, eosinophilic esophagitis, gastroesophageal reflux, or functional dysphagia from an esophageal clinic participated in a non-randomized, open-label trial. Acceptance, Commitment and COgnitive RemeDiation (ACCORD) was a novel 4-week BGBT administered via telemedicine. Feasibility and acceptability were assessed. Evaluations of esophageal symptom severity, cognitive and psychological flexibility, hypervigilance, symptom anxiety, and QoL occurred at baseline and posttreatment. Last observation carried forward was used for patients with incomplete 6-month data. Bayes Factor evaluated strength of support for study hypotheses.
Key Results: 89.9% of participants completed ACCORD. Moderate to decisive gains occurred for some markers of cognitive flexibility and psychological flexibility, which may demonstrate a delayed but strong improvement. Participants demonstrated strong to decisive reductions in symptoms, symptom anxiety, and decisive increases in health-related quality of life (HRQoL).
Conclusions And Inferences: A novel, four-session BGBT targeting cognitive and psychological flexibility in patients with esophageal disease was feasible, acceptable, and shows potential to improve symptom severity, symptom anxiety, and HRQoL. ACCORD's use of telemedicine may mitigate access issues related to BGBTs. Further study is warranted.
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http://dx.doi.org/10.1111/nmo.70150 | DOI Listing |
J Exp Anal Behav
September 2025
Oslo Metropolitan University, Norway.
Go/no-go successive matching (GNG-matching) tasks are one of several procedures used to establish conditional discriminations. This study presents a systematic review aimed at comparing procedures and outcomes of empirical studies using GNG-matching tasks for the emergence of symmetry, transitive, and global equivalence relations in humans and non-humans. A total of 22 articles were analyzed-nine with nonhumans and thirteen with humans.
View Article and Find Full Text PDFArch Clin Neuropsychol
September 2025
School of Psychology, Western Sydney University, Sydney, Australia.
Objective: Although traditionally associated with mild head trauma, post-concussive symptoms are commonly reported across both healthy and other clinical populations. Existing research indicates that individuals with depression report high levels of post-concussive symptoms, though the underlying causes of this association remain unknown. The current study aimed to explore potential factors underlying this relationship: specifically, how maladaptive and adaptive self-focused cognitive coping styles, namely, rumination and reflection, respectively, differentially contribute to post-concussive symptoms.
View Article and Find Full Text PDFFront Psychol
August 2025
School of Foreign Languages, Yulin Normal University, Yulin, China.
This mixed methods study explores the relationships among mindfulness, grit, self-regulation, and L2 boredom in Chinese undergraduate English majors. Using structural equation modeling (SEM) with a sample of 516 students from various universities, the quantitative phase found that mindfulness and grit were negatively related to L2 boredom, with self-regulation partially mediating these relationships. Mindfulness and self-regulation were the strongest predictors of reduced boredom, while grit had a smaller yet significant impact.
View Article and Find Full Text PDFOpen Access J Sports Med
August 2025
Division of Occupational Therapy and Physical Therapy; Division of Sports Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Background: Although exercises and physical activities are beneficial for overall health, it can unfortunately result in a musculoskeletal injury that requires a surgical intervention in physically active youth. One of the major injures young athletes sustain is anterior cruciate ligament (ACL) tear, which often requires a surgical intervention. Following the ACL reconstruction (ACLR) surgery, athletes need to participate in rehabilitation and often perform return-to-sport (RTS) testing.
View Article and Find Full Text PDFFront Neurosci
August 2025
School of Psychology, Hainan Normal University, Haikou, China.
Introduction: This study utilized electroencephalography (EEG) to compare brain functional and effective connectivity patterns in children with reading difficulties (RD) and math difficulties (MD) during specific tasks. The aim was to identify neurophysiological distinctions between these two learning disorders, which often exhibit high comorbidity.
Methods: Data from a publicly available dataset of 28 children (11 RD, 17 MD) aged 7-13 years were analyzed.