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Primary hypertension plays a crucial role in cardiovascular health and is potentially associated with hypertrophic cardiomyopathy (HCM). This study aimed to investigate the knowledge, attitude, and practice (KAP) of patients with primary hypertension toward HCM. This cross-sectional study was conducted among patients with primary hypertension at the Hospital between November 2023 and December 2023, using a self-designed questionnaire. A total of 840 valid questionnaires (532 males and a mean age of 45.12 ± 10.22 years) were collected. The mean KAP scores were 4.46 ± 4.33 (possible range: 6-30), 32.20 ± 3.90 (possible range: 8-40), and 33.31 ± 4.20 (possible range: 8-40), respectively. The structural equation modeling results showed that knowledge was influenced by education (β = 0.80, P < 0.001), medical insurance (β = 0.31, P = 0.001), HCM (β = 4.46, P < 0.001), family history of hypertension or cardiomyopathy (β = 1.39, P < 0.001), marital status (β = -0.96, P = 0.044), and duration of hypertension (β = -0.67, P < 0.001). Attitude was influenced by residence (β = -0.90, P = 0.001), medical insurance (β = -0.30, P = 0.001), HCM(β = 1.55, P < 0.001), and underlying diseases(β = 2.26, P < 0.001). Practice was influenced by attitude (β = 0.34, P < 0.001), residence(β = 0.70, P = 0.016), education(β = -1.60, P < 0.001), HCM(β = -0.84, P = 0.04), gender(β = 0.50, P = 0.041), history of hypertension or cardiomyopathy(β = -1.50, P < 0.001). Patients with primary hypertension have poor knowledge but positive attitudes and proactive practice toward HCM, which were affected by several sociodemographic characteristics. Educational interventions should be designed to improve knowledge.
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http://dx.doi.org/10.1038/s41598-025-17759-8 | DOI Listing |
Diabetes Obes Metab
September 2025
Department of Pharmacy, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan.
Aims: Chronic ocular diseases such as age-related macular degeneration (AMD) are leading causes of vision loss in older adults. While sodium-glucose co-transporter 2 inhibitors (SGLT2i) are widely prescribed in the management of type 2 diabetes mellitus (T2DM), their effects on ocular disease risk remain largely unknown.
Materials And Methods: This retrospective cohort study evaluated the association between SGLT2i use and the risk of AMD and other age-related ocular conditions in adults aged ≥60 with T2DM, using a target trial emulation framework based on the TriNetX global health research network (2013-2025).
J Hum Hypertens
September 2025
Division of Experimental Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, CB2 0QQ, UK.
The Stanley Peart Essay Competition is an annual event run by the British and Irish Hypertension Society to encourage Early Career Researchers to continue the ethos of Sir Stanley Peart. Sir Stanley Peart was a clinician and clinical researcher who made a major contribution to our understanding of blood pressure regulation. He was the first to demonstrate the release of noradrenaline in response to sympathetic nerve stimulation.
View Article and Find Full Text PDFObjectives: To investigate whether quantitative retinal markers, derived from multimodal retinal imaging, are associated with increased risk of mortality among individuals with proliferative diabetic retinopathy (PDR), the most severe form of diabetic retinopathy.
Design: Longitudinal retrospective cohort analysis.
Setting: This study was nested within the AlzEye cohort, which links longitudinal multimodal retinal imaging data routinely collected from a large tertiary ophthalmic institution in London, UK, with nationally held hospital admissions data across England.
Fitoterapia
September 2025
African Medicines Innovations and Technologies Development, Department of Pharmacology, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa.
Asteriscus graveolens (A. graveolens) belongs to the family Asteraceae. It is native to North Africa and the Asian deserts, with the majority of its distribution in Southwest Algeria and Southeast Morocco.
View Article and Find Full Text PDFJ Bras Pneumol
September 2025
. Universidade Federal de São Paulo, Escola Paulista de Medicina, São Paulo (SP) Brasil.
Objective: To describe the sociodemographic and clinical characteristics of individuals exposed to smoking or biomass smoke and followed at primary health care (PHC) centers across three states in Brazil.
Methods: This was a cross-sectional multicenter study including patients followed at any of four PHC centers in Brazil. Patients ≥ 35 years of age who were smokers or former smokers, or were exposed to biomass smoke were included, the exception being those with physical/mental disabilities and those who were pregnant.