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Objective: As artificial intelligence (AI) becomes increasingly integrated into graduate medical education, residency programs are exploring AI's role in application screening. Personal statements (PSs) remain a highly subjective yet influential component of the residency application. This study assesses the feasibility of using a large language model (LLM) to evaluate general surgery residency PSs compared to human-assigned scores.
Design, Setting, And Participants: We conducted a retrospective analysis of 668 deidentified PSs submitted to our general surgery residency program during the 2023-2024 application cycle. PSs were originally scored by human assessors (HA) using an anchored 1-5 scale in two domains: leadership and pathway. Each PS was subsequently scored by GPT-3.5 (AI) using the same rubric and standardized prompts. Descriptive statistics were used to compare AI and HA scores. Inter-rater agreement was assessed using weighted kappa coefficients. Discrepant cases (score differences >2 points) were reviewed qualitatively to identify scoring themes.
Results: AI and HA scoring showed low agreement: κ = 0.184 for leadership and κ = 0.120 for pathway domains. Median AI leadership scores were lower (3 [IQR 2-4]) than HA scores (4 [IQR 3-5]), while AI pathway scores were higher (4 [IQR 4-5]) than HA scores (3 [IQR 3-4]). Qualitative review revealed that AI required explicit labeling (e.g., formal leadership titles or stated adversity) to assign higher scores, whereas HA rewarded inferred qualities such as resilience, passion, and longitudinal commitment.
Conclusions: AI applied rubric-based scoring consistently but interpreted narrative content differently than human reviewers. While AI may enhance consistency and scalability in early application screening, its limitations in recognizing implicit meaning suggest human judgment remains essential for evaluating nuanced or inferential content. Caution should be exercised in adopting AI tools for subjective application review.
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http://dx.doi.org/10.1016/j.jsurg.2025.103655 | DOI Listing |
Int J Surg
September 2025
Department of Gynecology, Hainan General Hospital, Hainan Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China.
Background: Ovarian cancer remains the most lethal gynecological cancer, with fewer than 50% of patients surviving more than five years after diagnosis. This study aimed to analyze the global epidemiological trends of ovarian cancer from 1990 to 2021 and also project its prevalence to 2050, providing insights into these evolving patterns and helping health policymakers use healthcare resources more effectively.
Methods: This study comprehensively analyzes the original data related to ovarian cancer from the GBD 2021 database, employing a variety of methods including descriptive analysis, correlation analysis, age-period-cohort (APC) analysis, decomposition analysis, predictive analysis, frontier analysis, and health inequality analysis.
Appl Biochem Biotechnol
September 2025
Operating Room, Shanghai Tianyou Hospital, No.528, Zhennan Road, Putuo District, Shanghai, 200331, China.
Gastric cancer (GC) is a malignant tumor originating from the epithelial cells of the gastric mucosa. The 5-methylcytosine (mC) modification refers to the addition of a methyl group to the fifth carbon atom of cytosine in RNA molecules. This study aimed to investigate the role of NOL1/NOP2/SUN domain (NSUN)6 in GC and its underlying molecular mechanisms.
View Article and Find Full Text PDFGen Thorac Cardiovasc Surg
September 2025
Department of General Thoracic Surgery, Seirei Hamamatsu General Hospital, 2-12-12, Hamamatsu, Shizuoka, 430-8558, Japan.
Thoracoscopic surgery for stage III acute empyema is often limited by poor visualization and anatomical complexity. We developed a standardized, minimally invasive approach using a variable-view rigid endoscope and fixed port placement, regardless of disease extent or patient physique. The variable-view endoscope enabled a wide, adjustable field of view without moving the camera shaft, allowing safe access even in the confined thoracic space.
View Article and Find Full Text PDFJ Pathol
September 2025
The North of England Bone and Soft Tissue Tumour Service, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Indocyanine green (ICG) is a well-established near-infrared dye which has been used clinically for several decades. Recently, it has been utilised for fluorescence-guided surgery in a range of solid cancer types, including sarcoma, with the aim of reducing the positive margin rate. The increased uptake and retention of ICG within tumours, compared with normal tissue, gives surgeons a visual reference to aid resection when viewed through a near-infrared camera.
View Article and Find Full Text PDFEur Radiol Exp
September 2025
Department of Radio-diagnosis, Faculty of Human Medicine, Zagazig University, Zagazig, Egypt.
Background: Bone marrow (BM) lesion differentiation remains challenging, and quantitative magnetic resonance imaging (MRI) may enhance accuracy over conventional methods. We evaluated the diagnostic value and inter-reader reliability of Dixon-based signal drop (%drop) and fat fraction percentage (%fat) as adjuncts to existing protocols.
Materials And Methods: In this prospective two-center study, 172 patients with BM signal abnormalities underwent standardized 1.