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Background: The Timed Up and Go (TUG) test, commonly used to predict falls, has been enhanced with an inertial sensor, creating the Instrumented TUG (iTUG). Its reliability has been evaluated in a few studies involving neurological and heterogeneous orthopaedic populations.
Aim: The aim was to assess the intra-rater, inter-rater, and test-retest reliability of the iTUG in patients with femur fractures and define an interpretative model of the iTUG and a discriminative one to detect patients at risk of fall.
Methods: 201 inpatients with femur fractures underwent the iTUG test before discharge and a telephone follow-up at 1-month post-discharge to record falls. In a subgroup of 48 patients, iTUG data were used for assessing test-retest, intra-rater, and inter-rater reliability through Intra-class Correlation Coefficients. In the total sample, iTUG reliable variables were used for exploratory factor analysis and creating logistic regression models to identify the best predictive model for falls.
Results: 27/100 iTUG variables demonstrated "excellent" reliability; of those, 15 not-redundant variables were collected in a 3-factor model explaining 74 % of total variance. 92 % of patients completed the follow-up, and 5.5 % were classified as fallers. The fall risk model created with three iTUG variables showed an R= 0.31, with an AUC= 0.91.
Conclusion: The iTUG test is a reliable tool for assessing individuals with femur fractures, with 27 highly reliable variables. The 3-factor model offers a focused framework for gait evaluation, while the fall-risk model highlights the predictive value of iTUG variables, indicating that fall risk in the elderly depends on multiple gait characteristics. This article was awarded the SIAMOC Best Paper 2024.
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http://dx.doi.org/10.1016/j.gaitpost.2025.08.074 | DOI Listing |
Aging Cell
September 2025
San Francisco Coordinating Center, California Pacific Medical Center Research Institute, San Francisco, California, USA.
Entropy, characterized by increased disorder throughout biological systems, can be quantified by homeostatic dysregulation (HD). One potential measure of HD is the dispersion of points from a normal value, approximated at the individual level by Mahalanobis distance (D). We hypothesized that greater HD in electrocardiogram (ECG) would also reflect greater HD in the musculoskeletal system which, in turn, would be associated with age and manifest as an increased risk of fracture independently of age, bone mineral density (BMD), and history of fracture.
View Article and Find Full Text PDFJ Orthop Res
September 2025
Institute of Orthopaedic Research and Biomechanics, University Medical Center Ulm, Ulm, Germany.
Osteoporotic hip fractures are a considerable cause of pain and disability particularly among the elderly. Osteoporosis causes loss of bone stability, which in turn leads to an increased risk of fractures especially in metaphyseal bone. Moreover, the body's capacity for healing is diminished, resulting in prolonged recovery times following these fractures.
View Article and Find Full Text PDFBackground: Pressure injuries are common, difficult to manage, and carry a high economic burden. They are challenging to physicians and a burden to society.
Case Report: An 89-year-old male, who had previously undergone internal fixation with screws and rods for a right intertrochanteric fracture, developed a deep circular open ulcer measuring 11 cm × 7.
J Orthop Sci
September 2025
Department of Orthopaedic Surgery, NHO Saga Hospital, 1-20-1 Hinode, Saga 849-0923, Japan.
Background: Hounsfield units (HU) on computed tomography (CT) are strongly correlated with bone mineral density (BMD) and may aid in osteoporosis screening. However, there is no standardized method for assessing bone density in displaced femoral head fractures. This study aimed to measure HU values in the femoral head using preoperative post-fracture CT images of patients with intertrochanteric femoral fractures and investigate whether it correlated with BMD measured by dual-energy X-ray absorptiometry (DXA).
View Article and Find Full Text PDFInjury
September 2025
Department of Orthopedic Surgery, Hangzhou Xiaoshan Traditional Chinese Medical Orthopedic Hospital, Hangzhou, China.
Purpose: This study aims to evaluate the efficacy of nail dynamization in patients with delayed union and nonunion of femur and tibia shaft fractures following intramedullary nailing, and systematically analyze the associated factors to guide surgeons.
Methods: A comprehensive search of PubMed, EMBASE, and Cochrane Library databases was conducted to identify relevant studies. We screened the literature based on the eligibility criteria, extracted relevant data, and assessed the quality of the included studies.