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Introduction: As the prevalence of sleeve gastrectomy (SG) continues to rise each year, so does the number of patients requiring conversion to a hypoabsorptive procedure due to suboptimal results. While various types of bypass surgeries have been studied, available literature on transit bipartitions (TB) remains limited.
Methods: We conducted a retrospective analysis of patients who underwent conversion of SG to TB at our institution between November 1, 2017 and March 30, 2022. Three TB techniques were evaluated: one anastomosis sleeve-ileal TB (OATB), sleeve-ileal loop TB with Braun jejunoileostomy (B-TB), and TB with a Roux-en-Y formed small bowel short circuit (RYTB). Additional percentage of excess weight loss (%EWLadditional), percentage of total body weight loss (%TWL), and resolution of obesity-related comorbidities were the primary outcomes, while adverse effects were analyzed to assess the safety of each procedure.
Results: Of the 482 SG-to-TB conversions performed by March 2024, 171 patients with a complete follow-up (FU) of 2 years were included and matched by sex, age, and Body Mass Index (BMI) at the time of conversion. The %EWLadditional for OATB, B-TB, and RYTB at 2 years FU was 50.1, 53.4 and 54.3, respectively, with no significant differences in weight loss outcomes over time. OATB patients experienced more long-term adverse effects and showed a higher rate of reoperation.
Conclusiuon: TB after SG is a feasible and effective revisional procedure for achieving further weight loss and managing obesity-realated comorbidities. OATB, however, may be associated with a higher risk of long-term complications compared to other TB techniques.
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http://dx.doi.org/10.1007/s13304-025-02267-1 | DOI Listing |
Eur J Case Rep Intern Med
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Medical Subspecialities Department, Rheumatology Section, King Fahad Medical City, Riyadh, Saudi Arabia.
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August 2025
Department of Internal Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, USA.
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September 2025
School of Chemical Engineering, Minhaj University Lahore Lahore 54000 Punjab Pakistan.
Naomaohu lignite (NL) from Hami, Xinjiang, was ultrasonically extracted with a mixed solvent of CS and acetone (in equal volumes) to obtain the extract residue (ER). The ER was then separated based on density differences with CCl to yield the corresponding light residue (NL-L). The composition and structural characteristics of the light residue were characterized by proximate, ultimate, infrared, and thermogravimetric analyses (TG-DTG).
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Key Laboratory for Waste Plastics Biocatalytic Degradation and Recycling, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, China.
Polyurethane (PU), a segmented block copolymer with chemically resistant urethane linkages and tunable architecture, presents persistent biological recycling challenges. This study presents a Bacterial Laccase-Mediated System (BLMS) derived from for efficient degradation of polyester- and polyether-PU. Utilizing the laccase CotA and mediator 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), the BLMS demonstrated effective de polymerization of both commercial and self-synthesized PU foams, including polyester- and polyether-types.
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Beijing Life Science Academy, Beijing, China.
Hypocretin, also known as orexin, is a hypothalamic neuropeptide that regulates essential physiological processes including arousal, energy metabolism, feeding behavior, and emotional states. Through widespread projections and two G-protein-coupled receptors-HCRT-1R and HCRT-2R-the hypocretin system exerts diverse modulatory effects across the central nervous system. The role of hypocretin in maintaining wakefulness is well established, particularly in narcolepsy type 1 (NT1), where loss of hypocretin neurons leads to excessive daytime sleepiness and cataplexy.
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