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When roadways in strong mine pressure working faces traverse collapse columns, the complex stress redistribution frequently induces surrounding rock instability and support structure failure. This study investigates the 2702 intake airway crossing the X26 collapse column (75.8 m wide) at Zhangcun Coal Mine through an integrated approach combining theoretical analysis, numerical modeling, and field validation. Using elastoplastic mechanics theory and advanced numerical simulations (Midas GTS NX for 3D modeling and FLAC3D for stress analysis), we characterized the mechanical behavior of the collapse column structure zone, identifying distinct stress regions: a low-stress core zone (< 1 MPa), severe stress reduction zone (5 m radius), stress concentration zone (10 m radius, peak stress 15 MPa), and original rock zone. Theoretical calculations determined a plastic failure range of 50.01 m, informing the design of key engineering parameters: (1) optimized shallow-hole loose blasting with 0.5 m spacing, 1.6 m depth, and 0.6 kg charge per hole, creating effective pressure-relief zones; and (2) a 124.04 m strengthened support range. Numerical simulations demonstrated that the proposed "shallow-hole blasting + bolt-cable-mesh + π-steel shed" composite support system reduces plastic zone extent by 18% (from 195 to 160 mm), decreases roof subsidence by 6.6%, and limits sidewall deformation to < 200 mm. Field monitoring confirmed the system's effectiveness, maintaining roof displacement within 150 mm and ensuring structural integrity during the 75.8 m crossing. These results provide quantitative guidelines for roadway support design in collapse column areas under high mining-induced stresses.
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http://dx.doi.org/10.1038/s41598-025-15850-8 | DOI Listing |
J Behav Health Serv Res
September 2025
Department of Health Policy and Management, Fay W. Boozman College of Public Health, University of Arkansas for Medical Sciences, 4301 W. Markham St., Little Rock, AR, USA.
Telehealth is increasingly a standard and routine clinical option, indicating a changing outlook for SUD treatment from in-person to the more convenient option of telehealth. As populations across geographies increasingly prefer telehealth, more research is warranted that focuses on how where a person lives is associated with telehealth availability. The authors used the Mental Health and Addiction Treatment Tracking Repository (MATTR 2024) to identify telehealth availability among all known licensed SUD treatment facilities in the USA (N = 10,492 facilities).
View Article and Find Full Text PDFSci Total Environ
September 2025
Human Foods Program, U.S. Food and Drug Administration, College Park, MD, USA.
Cattle are a reservoir for the zoonotic human foodborne pathogen Shiga toxin-producing Escherichia coli (STEC), the causative agent of many disease outbreaks associated with contaminated fresh leafy greens. Concentrated animal feeding operations (CAFOs) housing cattle generate fugitive dust, however the potential risk of STEC movement by means of the aerosolized dust is not well known. In this investigation, we used metagenome sequencing of air samples collected in an agricultural setting to investigate airborne transfer of STEC from a large CAFO to the surrounding area.
View Article and Find Full Text PDFOncogene
September 2025
Division of Neurosurgery, Children's Hospital Los Angeles, Los Angeles, CA, USA.
It has become evident from decades of clinical trials that multimodal therapeutic approaches with focus on cell intrinsic and microenvironmental cues are needed to improve understanding and treat the rare, inoperable, and ultimately fatal diffuse intrinsic pontine glioma (DIPG), now categorized as a diffuse midline glioma. In this study we report the development and characterization of an in vitro system utilizing 3D Tumor Tissue Analogs (TTA), designed to replicate the intricate DIPG microenvironment. The innate ability of fluorescently labeled human brain endothelial cells, microglia, and patient-derived DIPG cell lines to self-assemble has been exploited to generate multicellular 3D TTAs that mimic tissue-like microstructures, enabling an in- depth exploration of the spatio-temporal dynamics between neoplastic and stromal cells.
View Article and Find Full Text PDFEcotoxicol Environ Saf
September 2025
CanmetMINING, Natural Resources Canada, Ottawa, ON, Canada. Electronic address:
Acid mine drainage (AMD) is a serious environmental problem at legacy and active mine sites around the world. Climate associated drought and rewetting events can increase the severity of AMD impacts through oxidation and release of stored metal(loid)s and acidity from contaminated sediments. The area surrounding Sudbury, Ontario, with its massive mining and smelting complexes, appears especially vulnerable to drought-driven effects.
View Article and Find Full Text PDFSci Rep
September 2025
Yunnan Provincial Transportation Planning and Design Research Institute Co., Ltd, Kunming, 650041, China.
Due to the high construction efficiency and low cost, double-arch tunnels without middle drift has been gradually promoted in engineering in recent years. However, the excavation characteristics of the left and right tunnels are easy to cause structural disturbance and deformation out of control. In particular, the surrounding rock disturbance of the front tunnel caused by the construction of the secondary tunnel often leads to lining cracking and structural instability.
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