98%
921
2 minutes
20
Renal leiomyosarcoma is a rare and aggressive tumor that comprises a very small proportion of adult kidney malignancies. Its clinical and imaging characteristics can closely resemble those of other high-grade renal tumors, which complicates the diagnostic process. We report the case of a 66-year-old male patient who presented with a large left renal mass and was diagnosed with high-grade pleomorphic leiomyosarcoma. He underwent radical nephrectomy along with en bloc removal of a para-aortic lymph node, which was histologically confirmed to contain metastatic disease. In an unusual postoperative development, the patient presented with a subcutaneous mass at the prior biopsy site. This was confirmed to be tumor seeding along the biopsy tract, an infrequent occurrence in renal sarcomas.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12381681 | PMC |
http://dx.doi.org/10.7759/cureus.88880 | DOI Listing |
Front Surg
August 2025
Urology Department, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Kidney cancer is the 14th most common cancer worldwide. On the basis of the histological characteristics of kidney cancers, most kidney cancers are renal cell carcinomas. Renal leiomyosarcoma (LMS) is extremely rare and malignant and accounts for less than 1% of all kidney cancer cases.
View Article and Find Full Text PDFCureus
July 2025
Urology, Alhada Armed Forces Hospital, Al Hada, SAU.
Renal leiomyosarcoma is a rare and aggressive tumor that comprises a very small proportion of adult kidney malignancies. Its clinical and imaging characteristics can closely resemble those of other high-grade renal tumors, which complicates the diagnostic process. We report the case of a 66-year-old male patient who presented with a large left renal mass and was diagnosed with high-grade pleomorphic leiomyosarcoma.
View Article and Find Full Text PDFAbdom Radiol (NY)
August 2025
Johns Hopkins Hospital, Baltimore, United States.
Inferior vena cava (IVC) leiomyosarcoma is a rare and aggressive malignancy arising from smooth muscle cells of the IVC wall, accounting for less than 1 in 100,000 adult malignancies. It carries a poor prognosis, with high recurrence rates and 5-year disease-free survival reported as low as 6%. Clinical presentation is often vague, including abdominal or back pain, lower extremity edema, and weight loss, making imaging pivotal for diagnosis.
View Article and Find Full Text PDFRadiol Case Rep
October 2025
Ultrasound Medical Center, The Second Hospital & Clinical Medical School, Lanzhou University, Cuiyingmen No. 82, Chengguan District, Lanzhou 730030, China.
A 62-year-old male patient was admitted to our hospital due to abdominal pain. Imaging studies, including computed tomography (CT) and ultrasonography, revealed a space-occupying lesion in the left renal hilar region. Postoperative pathological examination confirmed the diagnosis of retroperitoneal leiomyosarcoma with renal involvement.
View Article and Find Full Text PDFJ Int Med Res
August 2025
Department of Urology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Peking University Cancer Hospital Yunnan, China.
A woman in her early 50s was admitted to our hospital with a right retroperitoneal tumor that had been detected >1 year ago. Imaging studies revealed a mass in the right middle and lower retroperitoneum, which involved the upper portion of the right fallopian tube and caused dilated hydronephrosis of the right renal pelvis and calyces. Initial diagnosis suggested benign intraventricular smooth muscle neoplasia.
View Article and Find Full Text PDF