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Poland syndrome (PS) is a congenital anomaly characterized by unilateral hypoplasia or absence of the pectoralis major muscle, often associated with breast asymmetry. Achieving symmetry while preserving the contralateral breast remains a challenge in reconstruction. We present a case of a 19-year-old woman with left-sided PS, a fully developed right breast, and limited autologous soft tissue (body mass index 19.8 kg/m). A 2-stage approach was performed: initial tissue expansion followed by implant-based reconstruction with fat grafting. A 395-mL microtextured polyurethane implant was placed, and 130 mL of fat graft was injected to optimize contour. The procedures were uneventful, and the patient achieved satisfactory symmetry in size. However, nipple-areola height asymmetry occurred, which the patient declined to have corrected. This report expanded on previous literature by illustrating how a hybrid expander-implant-fat grafting approach was tailored to lean patients with PS, offering a reproducible and less invasive strategy compared with traditional flap-based reconstructions.
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http://dx.doi.org/10.1097/GOX.0000000000007076 | DOI Listing |
Front Endocrinol (Lausanne)
September 2025
Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland.
Isolated ectopic secretion of corticotropin-releasing hormone (CRH) is an exceedingly rare cause of Cushing's syndrome (CS), accounting for fewer than 1% of cases. Ectopic CS is an uncommon but potentially life-threatening condition that often necessitates urgent diagnostic evaluation and treatment. Hormonal testing may suggest a pituitary origin, complicating the diagnostic process.
View Article and Find Full Text PDFJ Anat
September 2025
Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Katowice, Poland.
Vertebrates exhibit remarkable morphological diversity, with the head representing an exceptionally complex anatomical structure shaped by adaptations to feeding ecology, brain size, and sensory organ specialization. Proper fusion of facial prominences and the coordinated growth of the skull and brain are essential for normal craniofacial development in vertebrates, including humans. Disruptions in these processes, whether due to gene mutations or external factors, can result in craniofacial malformations.
View Article and Find Full Text PDFClin Res Cardiol
September 2025
Department of (Interventional) Cardiology, Thoraxcenter, Erasmus University Medical Center, Room Rg-628, P.O. Box 2040, 3000 CA, Rotterdam, the Netherlands.
Background: Fractional flow reserve (FFR) for non-culprit lesions (NCLs) in patients with ST-elevation myocardial infarction (STEMI) can be influenced by temporary changes in microvascular resistance. Angiography-derived vessel fractional flow reserve (vFFR) has been tested as a less-invasive alternative.
Aims: The FAST STEMI II study aimed to assess the diagnostic performance of acute-setting vFFR vs.
Rhinology
September 2025
Department of Otolaryngology, Centre of Postgraduate Medical Education, Warsaw, Poland.
Background: Smell tests in children need to be standardized and validated, include odors familiar to children, and be defined by age-dependent standards. This study aimed to adapt the Sniffin Kids Test (SKT) for Polish children and conduct validation and evaluation of the Sniffin Kids Poland Test (SKPOL).
Methodology: The study included 382 children (4-14 years old) recruited in Poland, who were allocated into healthy (n=343) and sick (with subjective olfactory disorders, n=39), divided into 3 age subgroups, but also 13 anosmic children with Kallmann syndrome (KS) and olfactory bulb aplasia.
Neurocrit Care
September 2025
Department of Paediatrics, Cambridge University, Cambridge, UK.
Background: Low cerebral perfusion pressure (CPP) has previously been identified as a key prognostic marker after pediatric traumatic brain injury (TBI). Cerebrovascular autoregulation supports stabilization of cerebral blood flow within the autoregulation range. Beyond the upper limit of this range, cerebral blood flow increases with increasing CPP, leading to increased risk of intracranial hypertension and blood-brain barrier disruptions.
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