98%
921
2 minutes
20
Objectives: To compare the clinical and radiographic results of three approaches-involving particulate bone graft, recombinant human bone morphogenetic protein-2 (rhBMP-2)+absorbable collagen sponge (ACS), and no graft material-for lateral maxillary sinus augmentation with simultaneous dental implant placement.
Materials And Methods: From January 2015 to June 2021, a retrospective analysis was performed on 63 patients (a total of 122 implants) who underwent lateral maxillary sinus augmentation with simultaneous implant placement at the Department of Oral and Maxillofacial Surgery, Dong-A University Hospital. The patients were classified into three groups: no bone graft (n=46), particulate bone graft (n=44), and rhBMP-2+ACS graft material (n=32) groups. Panoramic and cone-beam computed tomography images taken before and after surgery were used to evaluate the residual bone height (RBH), postoperative bone height (POBH), bone density, and type of bone formation at the apex of the implant (BT). Additionally, the implant survival rates and postoperative complications were analyzed.
Results: The 1-year implant survival rate was similar across all three groups, exceeding 95%. The particulate bone graft group demonstrated the best clinical outcomes in terms of POBH and bone density, as well as the most active bone formation at the BT. The incidence of complications did not differ significantly among the three groups.
Conclusion: Although particulate bone graft was effective for bone formation and space maintenance, no significant differences were observed in the implant survival rate or complications compared with the other methods. The sinus augmentation outcomes did not vary considerably regardless of the type of bone graft material used.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405773 | PMC |
http://dx.doi.org/10.5125/jkaoms.2025.51.4.217 | DOI Listing |
Knee Surg Sports Traumatol Arthrosc
September 2025
UPMC Sports Surgery Clinic, Santry Demesne, Dublin, Ireland.
Purpose: Bone-patellar tendon-bone (BPTB) and Hamstring (HT) autografts are commonly used for anterior cruciate ligament reconstruction (ACLR). Concerns exist regarding postoperative anterior knee pain (AKP) and kneeling discomfort with BPTB grafts. However, many studies solely report the presence/absence of anterior knee pain, without assessing its clinical significance in terms of functional limitation or impact on quality of life.
View Article and Find Full Text PDFGut Liver
September 2025
Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
Background/aims: Despite medical advances in recent decades, the mortality rate of advanced liver cirrhosis remains high. Although liver transplantation remains the most effective treatment, candidate selection is limited by donor availability and alcohol abstinence requirements. Bone marrow-derived mesenchymal stem cell (BM-MSC) transplantation has shown promise for the treatment of advanced cirrhosis.
View Article and Find Full Text PDFInt Endod J
September 2025
Department of Biochemistry, School of Dentistry, IHBR, Kyungpook National University, Daegu, South Korea.
Aim: Prickle planar cell polarity (PCP) protein 2 (Prickle2) encodes a homologue of Drosophila prickle and is involved in the non-canonical Wnt/PCP signalling pathway. However, its exact role in dentinogenesis remains unclear. Dentinogenesis, a key process in tooth morphogenesis, involves the patterned arrangement of odontoblasts and the formation of dentine matrix along the pulp cavity.
View Article and Find Full Text PDFBest Pract Res Clin Haematol
September 2025
Department of Personalized Medicine and Rare Diseases, Medfuture Institute for Biomedical Research - Department of Hematology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Hematology, Ion Chiricuta Cancer Center, Cluj Napoca, Romania. Electronic address:
Plasma cell myeloma (multiple myeloma) is a blood cancer characterized by the clonal proliferation of plasma cells in the bone marrow. Treatment strategies evolve year by year, new drugs getting Food and Drug Administration (FDA)-approved each year. Chimeric antigen receptor (CAR) therapies are an advanced form of immunotherapy that engineer T cells to recognize and destroy cancer cells.
View Article and Find Full Text PDFBest Pract Res Clin Haematol
September 2025
Department of Personalized Medicine and Rare Diseases, Medfuture Institute for Biomedical Research - Department of Hematology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Hematology, Ion Chiricuta Cancer Center, Cluj Napoca, Romania. Electronic address: c
Lymphomas are a group of malignant proliferations of B, T or NK-lymphoid cells at different stages of maturation. While they primarily occur in lymph nodes or lymphatic tissues, they can also involve bone marrow, blood, or other organs. Despite advances in treatment, many patients experience relapse, or develop refractory disease, prompting the development of new therapies.
View Article and Find Full Text PDF